Cyclodextrin Complex
Formulation and Assessment of Mouth Dissolving Tablets of Repaglinide-ß-Cyclodextrin Complex
... Repaglinide-β- cyclodextrin complex was prepared in order to increase the solubility of ...Repaglinide-β-cyclodextrin complex was calculated, that shows the inclusion efficiency of 1:1 molar ...
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Preparation and Characterization of Holmium Beta Cyclodextrin Complex
... holmium-beta-cyclodextrin complex (Ho-β-CD) in order to increase the solubility and stability of ...CD complex was prepared by evaporation method of holmium and beta cyclodextrin solutions in ...
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FORMULATION AND IN VITRO EVALUATION OF SOLID DISPERSION OF β CYCLODEXTRIN COMPLEX OF GLIMEPIRIDE WITH POLOXAMER
... β- Cyclodextrin, F4 to F6 correspond to preparations containing Poloxamer 188 and F7 to F9 correspond to preparation containing combination of β-Cyclodextrin and Poloxamer ...
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Synthesis and Characterization Studies of Cisplatin/Hydroxypropyl-β-Cyclodextrin Complex
... molecules. Cyclodextrin complexation has been thoroughly investigated for bettering the unfavorable biopharmaceutical properties of drugs, such as poor solubility and/or stability 6 ...
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Enhanced Dissolution and In-Vivo Biavailability of Itraconazole Cyclodextrin Complex.
... 1. Improved solubility of Itraconazole in water significantly increased as the concentrations of HP-β-CYD increases, showing an AP type phase solubility diagram. The upward curvature closely corresponded to the ...
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Molecular Complexation of Silymarin and Its Biological Effect
... inclusion complex with beta (β)-cyclodextrin, using different ...inclusion complex of the drug with beta ...inclusion complex prepared by the co-precipitation methods exhibits an overall best ...
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Solid state characterization of domperidone: Hydroxypropyl-?-cyclodextrin inclusion complex
... inclusion complex of domperidone with hydroxylpropyl- β - cyclodextrin in order improved the solubility and hence to increase dissolution of ...-cyclodextrin complex was prepared in ratio 1:1 ...
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CYCLODEXTRINS: NANOCARRIERS FOR NOVEL DRUG DELIVERY
... Nanoparticles are considered as most stable system than liposomes. An approach in which cyclodextrins as stabilizers for the preparation of drug nanocrystals by the emulsion solvent diffusion method were studied by ...
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FORMULATION AND EVALUATION OF TINIDAZOLE MODIFIED RELEASE DOSAGE FORMS
... The main aim of the work is to investigate the effect of cyclodextrin complex with poorly soluble drug like Tinidazole. In this study we prepared various inclusion complexes by using solvent method. The ...
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Binding of the Inclusion Complex of Atorvastatin-β-cyclodextrin to Bovine Serum Albumin
... inclusion complex with ...β-cyclodextrin. Cyclodextrin modulated the binding of drug to the serum albumin, ...the cyclodextrin complex of Atorvastatin binds to bovine serum albumin with ...
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“Design and Evaluation of Fast Dissolving Tablets of Clobazam Using Complexation Technique” by Dhanalakshmi B, M.Vidyavathi, K. A.Sridhar, India.
... inclusion complex of Clobazam selected based on taste by direct compression ...drug complex (KF4- 1:2) equivalent to 10 mg Clobazam, superdisintegrants and other excipients were taken according to the ...
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PREPARATION AND EVALUATION OF TASTE MASKING COMPLEX OF CIPROFLOXACIN HYDROCHLORIDE BY USING INCLUSION COMPLEXATION APPROACH
... kneading complex of Ciprofloxacin HCl, β-Cyclodextrin were used for IR spectra and from the graph of IR spectra some peaks of β-Cyclodextrin overlap the peaks of Ciprofloxacin ...
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FORMULATION AND CHARACTERISATION OF AZITHROMYCIN DIHYDRATE INCLUSION COMPLEXES USING DERIVATIVES OF b-CYCLODEXTRINS AS COMPLEXING AGENTS
... ether cyclodextrin (SBECD) have been employed to investigate solubilising effect of cyclodextrins on poorly soluble ...β- cyclodextrin was treated with epichlorohydrin to synthesis epichlorohydrin- ...
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Effect of Polyvinylpyrrolidone on Complexation and Dissolution Rate of Beta Cyclodextrin and Hydroxypropyl Beta Cyclodextrin Complexes of Piroxicam
... The complexation of Piroxicam with β-CD and HP- β-CD was investigated by phase solubility studies. The phase solubility diagrams for the complex formation between Piroxicam and CDs in the presence and absence of ...
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A promising antitumor activity of evodiamine incorporated in hydroxypropyl-β-cyclodextrin: pro-apoptotic activity in human hepatoma HepG2 cells
... inclusion complex dif- fractogram was similar to that of amorphous HP-β-CD; however, no characteristic evodiamine peak was ...inclusion complex not showing the crystalline states indicated the formation of ...
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Journal of Applied Pharmaceutical Science
... (DXH) complex, using β-cyclodextrin (β-CD) and different hydrophilic polymers in order to enhance its solubility and dissolution ...ternary complex of DXH-β-CD-HPMC K4M. Ternary complex ...
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DESIGN AND DEVELOPMENT OF ORAL DISINTEGRATING TABLET OF SIMVASTATIN BY USING β CYCLODEXTRIN
... a complex of Simvastatin was prepared with β-cyclodextrin in (1:1) drug: polymer molar ratio by using kneading method and this complex was compressed into ...
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HYDROXYPROPYL β -CYCLODEXTRIN INCLUSION COMPLEX OF CURCUMIN USING FLUORESCENCE LIFETIME MEASUREMENT.
... Although safe in most cases, ancient treatments are ignored neither their active components nor their molecular targets are well defined. This is not the case, however, with curcumin, a yellow pigment substance and ...
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Enhanced dissolution and solubility of Epalrestat with β-Cyclodextrin ternary complex using Arginine
... The solubility behavior of EPL was examined in distilled water at room temperature (25 ± 2 °C) according to the method described by (Higuchi and Connors 1965) [15]. Excess amount of EPL(50mg) was added to 20 mL of ...
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INFLUENCE OF β-CYCLODEXTRIN COMPLEXATION ON KETOPROFEN RELEASE FROM MATRIX FORMULATION
... the complex in to membrane, addition of β-CD to the matrix increased flux by increasing the solubility of Ketoprofen, thus improving the diffusible form of the drug species at the tablet membrane ...the ...
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