D galactosamine
“Ameliorative Effect of Piperine from Piper Nigrum on D-Galactosamine - Induced Hepatotoxicity in Mice” by Evan Prince Sabina, Mahima Vedi, Mahaboobkhan Rasool, Kavitha Murugan, Deborah Jackline, India.
... II- D-galactosamine ...IV- D-galactosamine + Silymarin ...vs D-GalN; b-D-GalN vs Piperine+D-GalN; c-Silymarin vs. D- ...
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HEPATOPROTECTIVE ACTIVITY OF HYDROALCOHOLIC EXTRACT OF BOERHAAVIA DIFFUSA LINN AGAINST D GALACTOSAMINE INDUCED HEPATOTOXICITY IN MICE
... in D-Galactosamine intoxication of mice, particularly noticeable with the high dose used by us (400 mg/kg body ...in D- Galactosamine-induced hepatitis in ...
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Hepato Protective and Antioxidant Activity of Cnidoscolus Phyllacanthus against D- Galactosamine induced oxidative strees in Rats.
... the D-galactosamine rats might be due to an antioxidant defense against increased ROS or due to a decrease in glutathione levels in D-galactosamine-hepatotoxic rats (92) ...in D- ...
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HEPATOPROTECTIVE ACTIVITY OF HYDROALCOHOLIC EXTRACT OF OPERCULINA TURPETHUM LINN. AGAINST D-GALACTOSAMINE INDUCED HEPATOTOXICITY IN RATS
... The genus Operculina has potential activity as a hepatoprotective agent. The present pharmacological investigation focuses on evaluation of the efficacy of hydroalcoholic extract of roots of Operculina turpethum Linn. ...
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ANTIOXIDATIVE EFFECT OF EPIGALLOCATECHIN GALLATE AGAINST D-GALACTOSAMINE-INDUCED INJURY IN PRIMARY CULTURE OF RAT HEPATOCYTES
... monolayers, the medium was removed and replaced with a fresh supplemented medium without fetal bovine serum containing dissolved epigallocatechin gallate at different concentrations of 1.25, 2.5, 5 and 10 μM and toxic ...
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IN VITRO AND IN VIVO ANTI HEPATOTOXIC EVALUATION OF ALPINIA GALANGA ON D GALACTOSAMINE INDUCED TOXICITY
... the D- Galactosamine induced hepatotoxicity, whereas at the concentration of 600 and 800 μg/ml it was found to be cytotoxic for both the hydro alcoholic extracts prepared by cold and hot maceration ...to ...
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Antioxidant and Hepatoprotective Potential of Traditional Siddha Formulation Seenakara Parpam against D Galactosamine Induced Oxidative Stress in Rats
... against D-galactosamine induced oxidative stress in ...of D- galactosamine at the dose of 400 mg/kg to all the rats except control ...with D-galactosamine 400 mg/kg (Group II) as ...
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Surface modifications in the platelets of a patient with alpha N acetyl D galactosamine residues, the Tn syndrome
... The Tn-syndrome is an acquired disorder characterized by the polyagglutination of blood cells and the pathological exposure of alpha-N-acetyl-D-galactosamine residues (Tn- antigen) at the cell surface. We ...
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HEPATOPROTECTIVE ACTIVITY OF HERBAL PREPARATION (HP-4) AGAINST D-GALACTOSAMINE INDUCED HEPATOTOXICITY IN MICE
... reactions. D-Galactosamine (D-GalN) is a well known ...of D-GalN hepatotoxicity. D-GalN hepatotoxicity induces liver injury closely resembling human viral hepatitis with necrosis, ...
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HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITY OF CNIDOSCOLUS CHAYAMANSA AGAINST D-GALACTOSAMINE INDUCED LIVER DAMAGE IN RATS
... in d-galactosamine (d-GalN)-induced hepatotoxicity in ...activity. d-GalN administration induced hepatotoxicity in rats which was manifested by increased levels of serum alanine ...
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Attenuation of Oxidative Stress and Hepatotoxicity Induced By D–Galactosamine by a Polyherbal Formulation Ambrex–in vivo and in vitro Studies
... against D–galactosamine (D-GLN) induced hepatotoxicity in Swiss albino mice as well as in Chang liver cell ...b.wt. D-GLN (250 mg/kg ...by D - GLN. In vitro studies revealed that Ambrex ...
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Dual endothelin-converting enzyme/neutral endopeptidase blockade in rats with D-galactosamine-induced liver failure
... groups: controls (con; n = 9), controls with slv338 treatment (con+slv; n = 9), D-galactosamine (galn; n = 20) and D-galactosamine with slv338 treatment (galn+slv; n = 20). slv338 (or vehicle) ...
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The Model of D-Galactosamine-Induced Injury of Rat Hepatocytes in Primary Culture
... Summary: D-galactosamine (GalN) is a highly selective hepatotoxin that causes liver damage similar to human viral hepa- titis via depletion of uridine nucleotides, which subsequently diminishes synthesis of ...
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Hepatoprotective Activity of Methanolic Extract of Flacourtia sepiaria ROXB against D-Galactosamine Induced Oxidative Stress in Rats
... view. Galactosamine has considerable liver specificity because hepatocytes have high levels of galactokinase and galactose-1-P-uridylyltransferase while other organs do ...protection Galactosamine-induced ...
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Modulatory effect of Morin on D-Galactosamine induced hepatotoxicity in rats
... liver D-galactosamine rats, which might be due to reduced the oxidative stress, decrease the collagen content and reduce the bundles of collagen fibers ...
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Phytochemistry and Hepatoprotective Activity of Chloroform Extract of NKC Ingredient in Santalum album Against D-Galactosamine Induced Hepatotoxicity in Rats
... It is confirmed that chloroform extract of Santalum album inhibited lipid peroxidation. The antioxidant present in the extract accounts for the inhibition of lipid peroxidation. The anti-hepatotoxic activity of the ...
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Hepatoprotective Potential of Lycopene on D-Galactosamine/Lipopolysaccharide Induced Hepatitis in Rats
... against D-Galactosamine/Lipopolysaccharide (D-GalN/LPS) induced hepatitis in ...of D-GalN/LPS (300 mg/kg body weight and 30 µg/kg body weight) to induce liver ...before D-GalN/LPS ...
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A novel scoring system for prognostic prediction in d-galactosamine/lipopolysaccharide-induced fulminant hepatic failure BALB/c mice
... Results: 28 mice of survival group and 28 of dead group were randomly selected and analyzed. PLS regression analysis showed that both the PLS models of 5 h and 6 h after d-galactosamine/ lipopolysaccharide ...
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Green tea extract supplement reduces D-galactosamine-induced acute liver injury by inhibition of apoptotic and proinflammatory signaling
... whether D-galactosamine (D-GalN) induces ALI via the mitochondrial apoptosis- and proinflammatory cytokine-signaling pathways, and possible mechanism(s) by which green tea (GT) extract modulates the ...
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Metabonomic analysis of liver tissue from BALB/c mice with d-galactosamine/lipopolysaccharide-induced acute hepatic failure
... to vary following liver diseases, and in different types of liver dysfunction, the variation may be different. ALF almost certainly results in significant changes of liver metabolites because of its rapid and severe ...
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