Dahl salt-sensitive rats
Mechanisms of pressure-diuresis and pressure-natriuresis in Dahl salt-resistant and Dahl salt-sensitive rats
... Mechanisms of pressure-natriuresis and pressure-diuresis Using a simple mathematical model to simulate blood flow regulation, glomerular filtration, and medullary sol- ute transport in the kidney, we have analyzed data ...
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Low Salt Diet in Pregnant Mothers Is Associated with Enhanced Salt Appetite in Their Offspring of Dahl Salt Sensitive Rats
... Interestingly, recent studies have highlighted the role of life-style of mothers during gestation in the develop- ment of hypertension and metabolism-related diseases in adulthood. In fact, some investigators have ...
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The exenatide analogue AC3174 attenuates hypertension, insulin resistance, and renal dysfunction in Dahl salt-sensitive rats
... high salt DSS rats, more than 75% of the area of the glomerular capillaries can be filled with matrix material, indicating a high degree of glomerular injury ...low salt DSS rats ...high ...
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Continuous Subcutaneous Administration of Miso Extracts Attenuates Salt Induced Hypertension in Dahl Salt Sensitive Rats
... the salt-intake (intake range, 4 to 8 g/day), suggesting that blood pressure is related not only to salt-intake, but also to intake of various nutrients in a balanced ...attenuate salt dependent ...
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Activation of the Fas/Fas ligand pathway in hypertensive renal disease in Dahl/Rapp rats
... the Dahl/Rapp salt-sensitive (S) rat, which develops hypertensive nephrosclerosis that resem- bles the human disease process [5], this laboratory dem- onstrated an early and inappropriate apoptotic ...
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Prestroke Proteomic Changes in Cerebral Microvessels in Stroke-Prone, Transgenic[hCETP]-Hyperlipidemic, Dahl Salt-Sensitive Hypertensive Rats
... transgenic-hyperlipidemic Dahl salt-sensitive (Dahl-S) rat, Tg25sp model with sex-specific differences (8) provides a strategic model for molecular analysis of the cerebral ...
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A multi-component model of the dynamics of salt-induced hypertension in Dahl-S rats
... of salt on BP (ie. acute salt sensitivity, corresponding with a depressed slope of the chronic pressure natriuresis ...high salt intake on BP (corresponding with a progressive salt-induced ...
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The Dual AngII/AVP Receptor Gene N119S/C163R Variant Exhibits Sodium-Induced Dysfunction and Cosegregates With Salt-Sensitive Hypertension in the Dahl Salt-Sensitive Hypertensive Rat Model
... to salt-sensitive hyperten- sion susceptibility, we performed an intercross link- age analysis on 105 F2 (Dahl S Dahl R ) hy- brid male rats phenotyped for BP by radiotelemetry after 8 ...
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Rac1 GTPase in rodent kidneys is essential for salt sensitive hypertension via a mineralocorticoid receptor–dependent pathway
... excess salt in cardiorenal dysfunction are ...of salt-sensitive hypertension, leading to blood pressure elevation and renal injury via an MR-dependent ...in salt-sensitive Dahl ...
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Locus for the inducible, but not a constitutive, nitric oxide synthase cosegregates with blood pressure in the Dahl salt sensitive rat
... Alleles of the inducible nitric oxide synthase locus (Nos2) cosegregated highly significantly (P < 0.0001) with blood pressure in an F2 population [F2(S x MNS), n = 171] derived from a cross of inbred Dahl ...
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α 1 Na,K-ATPase and Na,K,2Cl-Cotransporter/D3mit3 Loci Interact to Increase Susceptibility to Salt-Sensitive Hypertension in Dahl SHSD Rats
... to salt- sensitive hypertension susceptibility, we performed cosegregation analysis on 96 F2 (Dahl S male Dahl R female) hybrid male rats characterized phe- notypically for systolic ...
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Effects of renin gene transfer on blood pressure and renin gene expression in a congenic strain of Dahl salt resistant rats
... the Dahl salt-sensitive (S) rat, a widely studied model of salt-sensitive hypertension, Rapp et ...from Dahl S and Dahl salt-resistant (R) rats, the BP of ...
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Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats
... in Dahl S versus R ...S rats [16] might as well enhance serine phosphorylation on IRS-1 and/or IRS-2 and explain insulin resistance in Dahl S ...
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L arginine abrogates salt sensitive hypertension in Dahl/Rapp rats
... young Dahl/Rapp salt-sensitive (SS/Jr) and salt-resistant (SR/Jr) ...in salt-resistant rats, but not in salt-sensitive ...in salt-sensitive ...
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The alpha1 Na,K ATPase gene is a susceptibility hypertension gene in the Dahl salt sensitiveHSD rat
... using Dahl salt- sensitive (S) and Dahl salt-resistant (R) rats ascertained for genotype and ...the Dahl S Q276L a 1 Na,K-ATPase gene variant, we developed transgenic ...
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Hypertension Exacerbates Coronary Artery Disease in Transgenic Hyperlipidemic Dahl Salt-sensitive Hypertensive Rats
... As observed in human acute coronary syn- dromes, we detected lesion heterogeneity with at least four lesion phenotypes in end-stage Tg53 rat hearts. Representative composites of heart serial sec- tions from end-stage ...
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Effects of salt-loading hypertension on nociception in rats
... and latency period were not significantly different in the two groups before administration of salt-loaded diet further suggested that the observed hypoalgesia after its treatment was undoubtedly induced by ...
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Salt resistance of tomato species grown in sand culture
... Salt stress is recognized as a major factor that limits plant growth, physiology and productivity, mainly by inducing osmotic effects, ion-specific effects and oxidative stress (Okhovatian-Ardakani et al. 2010). ...
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Increased dynamin expression precedes proteinuria in glomerular disease
... RNA isolation, reverse transcription, and qPCR RNA was isolated from rat glomeruli using TRIzol (Invitrogen, Waltham, MA, USA). AMV reverse tran- scriptase (Roche Diagnostics, Risch-Rotkreuz, Switzer- land) was used to ...
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AS WELL AS ACTIVITY AND MOLECULAR FORMS OF RIBONUCLEASE IN GERMINATING RICE SEEDS DIFFERING IN SALT TOLERANCE RENU MI1TAL AND R.S. DUBEY
... Salt treatment caused increase in RNase activity in embryoaxes of salt sensitive cultivars specially during 48-120 h of germination whereas in salt tolerants salinity level o[r] ...
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