DBA/2 mice
mGluR1,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice
... a DBA/2 mouse (p < ...experimental DBA/2 mice (n = 7) before (black symbols and line) and after (red) washing-on DHPG (p < ...in DBA/2 ...in DBA/2 ...
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Characterization of a Polytropic Murine Leukemia Virus Proviral Sequence Associated with the Virus Resistance Gene Rmcf of DBA/2 Mice
... of DBA/2 mice with Rmcf-medi- ated resistance in order to permit identification of a specific provirus associated with Rmcf-mediated ...virus-resistant DBA/2N substrain mice but not by ...
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Identification of hepatocarcinogen-resistance genes in DBA/2 mice.
... Interestingly, the distribution of mean tumor multiplicities among BXD recom- binant inbred strains indicated that hepatocarcinogen-sensitive DBA/2 mice carry multiple genes [r] ...
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Poorly expressed endogenous ecotropic provirus of DBA/2 mice encodes a mutant Pr65gag protein that is not myristylated.
... For example, DBA/2 mice that carry Emv-3 as their sole endogenous ecotropic provirus do not express detectable ecotropic virus until about 5 months of age, and then only about one-third [r] ...
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Spontaneous expression of C-type virus in DBA/2 mice is associated with an increased rate of mortality, independent of neoplastic disease.
... Because young viremic DBA/2 mice appeared healthy and because ecotropic viruses isolated from viremic DBA/2 mice caused an increased incidence of leukemia as well as premature death from[r] ...
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A replication-competent, endogenous retrovirus from an aged DBA/2 mouse contains the complete env from Emv-3 and a novel gag partially related to AKT-8.
... the DBA/2 mouse genome contains a complete endogenous retrovirus sequence, Emv-3, only spo- radic endogenous ecotropic virus production is found in young DBA/2 mice ...young ...
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Vulnerability to cocaine: role of stress hormones
... chapter 2 the hypotheses are tested that i) adrenal stress hormones contribute to cocaine sensitivity and ii) this may depend on the genetic make-up of the ...purpose mice of the C57BL/6 and ...
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The DBA.2 Mouse Is Susceptible to Disease following Infection with a Broad, but Limited, Range of Influenza A and B Viruses
... that DBA.2 mice are highly suscep- tible to H5N1 influenza viruses (2) as well as the mouse- adapted strain A/Puerto Rico/8/1934 (H1N1) (PR8) ...C57BL/6 mice (3). For these reasons, use ...
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Cross-Reactive Neutralizing Antibodies Directed against Pandemic H1N1 2009 Virus Are Protective in a Highly Sensitive DBA/2 Mouse Influenza Model
... of DBA/2 mice for influenza virus infections was used to demonstrate the effectiveness of H1N1pdm cross-neutralizing human antibodies in reducing H1N1pdm-driven ...when mice were injected with ...
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Mixed-strain housing for female C57BL/6, DBA/2, and BALB/c mice: validating a split-plot design that promotes refinement and reduction
... BALB/c mice were consistently more stereotypic than C57BL/6 mice [11, 18]; BALB/c and C57BL/6 were con- sistently most anxious, in behavioural tests of anxiety, followed by DBA/2 s [18, 52]; ...
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Comparative Efficacy of Monoclonal Antibodies That Bind to Different Epitopes of the 2009 Pandemic H1N1 Influenza Virus Neuraminidase
... of DBA/2 mice against lethal wild-type pH1N1 virus challenge; however, at a lower dose (1 mg/kg), HF5 protected ⬃ 90% of mice, whereas CD6 protected only 25% of ...of mice against ...
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Effects of the route of infection on immunoglobulin G subclasses and specificity of the reovirus-specific humoral immune response.
... Mucosal administration of antigen can elicit both local and systemic antibody responses. These humoral responses are typ- ically characterized by the appearance of immunoglobulin A (IgA) in secretions and IgG in serum ...
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PubMedCentral-PMC5438921.pdf
... studies 2 and 3 at the outset of the study, the Green line IVC rack and autoclavable hoses (part ...every 2 wk, the dirty cages with feed and bedding were autoclaved prior to disassembling them for ...the ...
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VISTA deficiency attenuates antibody induced arthritis and alters macrophage gene expression in response to simulated immune complexes
... V-KO mice. CAIA was induced in DBA/1 J mice by IP injection of ...afterward. Mice were treated by IP injections of monoclonal antibodies (100 μg MH5A or 300 μg 8G8) or control hamster IgG ...
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Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre Sertoli cells
... involving mice from the two inbred strains C57BL/6JEi (B6) and DBA/2J (D2) were ...XY mice are exceptionally sensitive to disturbances in the early events of testicular development and thus provide a ...
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Pathophysiology, assessment and treatment of psoriatic dactylitis
... Fig. 2 | Enthesitis and osteitis in dactylitis. a | 42-year-old female with 4-year history of psoriatic arthritis with associ- ated dactylitis of the right second toe. b | T1-weighted fat-suppressed post-contrast ...
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Intergenerational genomic DNA methylation patterns in mouse hybrid strains
... F1 mice and the parental mice, since the parental mice are inbred and both alleles have the same genotype on both alleles, and hence AMRs could not be caused by allele- specific ...
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Dichloroacetate alleviates development of collagen II induced arthritis in female DBA/1 mice
... female mice in CIA (Figure 4a) as a result of increased cortical thickness (Fig- ure ...female mice, but not male or OVX-treated female mice, benefited from DCA ...
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IgG glycoforms in arthritis
... cartilage. The synovial membrane which surrounds and maintains the joint space becomes intensely cellular as a result of considerable immunological hyperactivity as evidenced by large numbers of T-cells, mostly CD4, in ...
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Cell-mediated immunity induced in mice after vaccination with a protease activation mutant, TR-2, of Sendai virus.
... Spleen cells, prepared from DBA/2 or C3H/He mice on day 69 or 51 postinfection, respectively, were incubated in vitro with either UV-inactivated wild-type Sendai virus shaded column or X[r] ...
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