DC, dendritic cell
The DC-SIGN-CD56 interaction inhibits the anti-dendritic cell cytotoxicity of CD56 expressing cells
... neg DC-SIGN-L pos cells as CD3+/−CD56 + CD11b + CD16 + CCR5-CXCR4- ...(Neural Cell Adhesion Molecule; an NK-and neuron-specific anti- gen) cell surface expression suggests that these cells belong to ...
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Peripheral regulatory cells immunophenotyping in Primary Sjögren's Syndrome: a cross sectional study
... B cell activating factor; BCR: B cell receptor; CpG: cytosine-phopsphate-guanosine; DC: dendritic cell; DCregs: indoleamine 2,3-dioxygenase-expressing dendritic cells; ESSDAI: ...
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Galectin 9 prolongs the survival of septic mice by expanding tim 3 expressing natural killer T cells and PDCA 1+ CD11c+macrophages
... puncture; DC: Dendritic cell; ELISA: Enzyme-linked immunosorbent assay; FACS: Fluorescence- activated cell sorting; FCS: Fetal calf serum; Gal-9: Galectin-9; HMGB1: High mobility group box 1; ...
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Randomized phase II trial of autologous dendritic cell vaccines versus autologous tumor cell vaccines in metastatic melanoma: 5-year follow up and additional analyses
... onto DC outside of the im- munosuppressive tumor environment may be especially advantageous in patients who have normal expression of major histocompatibility antigens, but have no infiltration of CD8+ ...
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<p>T cells targeting multiple tumor-associated antigens as a postremission treatment to prevent or delay relapse in acute myeloid leukemia</p>
... immunoregulatory antibodies, vaccines, and adoptive cell infusion. 2 The direct clinical evidence of antileukemia- speci fi c cytotoxic T lymphocytes (CTLs) originated from the relapse of chronic myeloid leukemia ...
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Local synthesis of interferon alpha in lupus nephritis is associated with type I interferons signature and LMP7 induction in renal tubular epithelial cells
... blood dendritic cell antigen 2; DAB: 3,3 ′ -diaminobenzidine; DC: dendritic cells; DIG: digoxigenin; dsRNA: double-stranded ribonucleic acid; DTX3L: deltex 3 like, E3 ubiquitin ligase; FBS: ...
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Eliciting cytotoxic T lymphocytes against human laryngeal cancer-derived antigens: evaluation of dendritic cells pulsed with a heat-treated tumor lysate and other antigen-loading strategies for dendritic-cell-based vaccination
... study, DC-TSL pulsing was the only effective method to prime CD8 + and CD4 + T ...T cell and DC-TSL co-culture, which strongly supports the choice of TSL-pulsed as a promising CTL activator against ...
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Impaired Accessory Cell Function in a Human Dendritic Cell Line after Human Immunodeficiency Virus Infection
... human DC hybrid- oma cell lines that we used to study DC function after HIV ...human DC hybridomas were obtained by allow- ing peripheral blood monocytes to become immature DCs by treatment ...
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Original Article Efficacy analysis of triple-negative breast cancer patients treated with dendritic cell-cytokine-induced killer cell immunotherapy
... of dendritic cell-cytokine-induced killer (DC-CIK) cell immunotherapy combine with chemotherapy with or without radiotherapy for triple-negative breast cancer (TNBC) patients following ...of ...
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Introduction to dendritic cell vaccines immunotherapy for glioblastoma multiforme : A novel approach
... by cell counter, suitability with flowcytometry specifications, have specific morphology of dendritic cells, and the environmental monitoring must be within particular ...before DC vaccines are ...
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Characterization of DC-SIGN/R Interaction with Human Immunodeficiency Virus Type 1 gp120 and ICAM Molecules Favors the Receptor's Role as an Antigen-Capturing Rather than an Adhesion Receptor
... The dendritic cell (DC)-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin binding receptor (DC-SIGN) was shown to bind human immunodeficiency virus type 1 (HIV-1) viral ...
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Schnorfeil, Frauke Marie (2011): MicroRNAs regulate Dendritic Cell Development and Function. Dissertation, LMU München: Medizinische Fakultät
... in DC sub- set development as Kit, encoding for c-Kit protein, is expressed on a recently identified DC progenitor (Naik et ...mature DC subsets by flow cytometry after inhibition of these miRNAs ...
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Correlation of variable repeat number in the neck regions of DC-SIGN and DC-SIGNR with susceptibility to nasopharyngeal carcinoma in a Chinese population
... of DC-SIGN on the host cell ...of DC-SIGN neck region repeats may influ- ence host susceptibility to many infectious diseases involving bacteria, virus, and ...the DC-SIGN repeat region may ...
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Generation of donor specific Tr1 cells to be used after kidney transplantation and definition of the timing of their in vivo infusion in the presence of immunosuppression
... donor-derived DC-10 ...for DC-10 generation. Based on the MLR/DC-10 protocol used in the ALT-TEN trial [7], DC-10 were gen- erated from the PBMC adherent fraction in medium sup- plemented with ...
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Microbes, the gut and ankylosing spondylitis
... Macrophages patrol the gastrointestinal systems in high numbers. Th ey frequently come in contact with ‘stray’ bacteria, including commensals that have breached the epithelial cell barrier. Macrophages phagocytose ...
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Fluorine-19 MRI for detection and quantification of immune cell therapy for cancer
... immune cell therapy has emerged as a potent treatment for multiple cancers, first through groundbreaking leukemia therapy, and more recently, by tackling solid ...Assaying cell biodistribution is ...
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Long noncoding RNA expression profile and association with SLEDAI score in monocyte derived dendritic cells from patients with systematic lupus erythematosus
... lincRNA-Cox2, a critical inflammation mediator, was in- duced in bone marrow-derived DCs after stimulation with LPS [29]. A further study revealed that lincRNA-Cox2 mediated both the activation and repres- sion of ...
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Myeloid dendritic cells correlate with clinical response whereas plasmacytoid dendritic cells impact autoantibody development in rheumatoid arthritis patients treated with infliximab
... pDC cell surface and the subsequent internalization and delivery of the self-DNA or self-RNA within the complex to intracellular TLR9 or TLR7, respectively ...
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The within host dynamics of Mycobacterium avium ssp. paratuberculosis infection in cattle: where time and place matter
... recent data support the role of macrophage produced IL-10 in down regulation of Th1/IFN-γ responses and disease progression in MAP infected cattle [16]. How- ever Shu et al. showed a marked upregulation of both pro- and ...
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Disturbance of cytokine networks in Sjögren's syndrome
... The diffi culty in predicting the consequences of interactions between diff erent cytokine networks has increased with the expansion of the T helper (Th) cell universe and the discovery of numerous B ...
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