DC Maturation
12/15 lipoxygenase–mediated enzymatic lipid oxidation regulates DC maturation and function
... a maturation process, which is a prerequisite for initiating specific T cell ...responses. DC maturation involves a change in the pattern of secreted cytokines as well as the upregu- lation of ...
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Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion
... fewer than 10% of BMCs were infected (i.e., day 5 after infection), an inhibitory effect on DC development was noted (see Figure 2). Thus, Cl 13 may have the capacity to impair the expansion of progenitor cells by ...
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Analysis of proteomic profiles and functional properties of human peripheral blood myeloid dendritic cells, monocyte derived dendritic cells and the dendritic cell like KG 1 cells reveals distinct characteristics
... both DC models, are known to play important roles in maintaining cell structure and in the formation of immuno- logical synapses between DCs and T cells ...with DC maturation state, and recent work ...
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Tumour Tissue Microenvironment Can Inhibit Dendritic Cell Maturation in Colorectal Cancer
... Interestingly CXCL1 and VEGF have an additive inhibitory effect on IL-12p70 secretion. They act on different receptors which have previously been shown to be present on DCs [7,19], therefore they might activate different ...
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Consequences of Fas-Mediated Human Dendritic Cell Apoptosis Induced by Measles Virus
... MV-infected DC-activated T-cell cocul- tures. We showed here that MV-induced DC apoptosis was Fas ...MV-infected DC was demonstrated to be TRAIL mediated (39), this death ligand may be responsible ...
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Herpes Simplex Virus 2 (HSV-2) Prevents Dendritic Cell Maturation, Induces Apoptosis, and Triggers Release of Proinflammatory Cytokines: Potential Links to HSV-HIV Synergy
... the maturation marker CD83 was observed in response to HSV-2 and HSV-2 exposed DCs were impaired in their ability to present antigen (influenza) to T ...in DC matu- ...promotes DC maturation ...
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Interplay between Modified Vaccinia Virus Ankara and Dendritic Cells: Phenotypic and Functional Maturation of Bystander Dendritic Cells
... soluble factors produced by DCs after MVA infection that have previously been reported to induce maturation. Pro- inflammatory cytokines, such as IL-6, TNF- ␣ , and IL-1  , would be strong candidates; ...
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Hepatitis B Virus Surface Antigen Activates Myeloid Dendritic Cells via a Soluble CD14-Dependent Mechanism
... HBsAg-induced DC maturation and ...insufficient DC activation due to low sCD14 levels may be one of the factors contributing to inadequate HBV-specific immunity in HBV-infected ...⫹ DC that we ...
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Double-Stranded RNA Analog Poly(I:C) Inhibits Human Immunodeficiency Virus Amplification in Dendritic Cells via Type I Interferon-Mediated Activation of APOBEC3G
... other maturation stimuli did not lead to DC ...of DC maturation after exposure of virus-loaded DCs to the different ...poly(I:C) maturation was more effective at limiting HIV ...
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The Number of Toll-Like Receptor 9-Agonist Motifs in the Adenovirus Genome Correlates with Induction of Dendritic Cell Maturation by Adenovirus Immune Complexes
... of DC maturation (as assessed by both costimulatory molecule expression and cytokine production) through Fc␥R internaliza- tion and Toll-like receptor 9 (TLR9) interaction ...IC-mediated DC ...
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Nonstructural Proteins 1 and 2 of Respiratory Syncytial Virus Suppress Maturation of Human Dendritic Cells
... increased DC matura- tion would be consistent with this ...of maturation markers ...human DC maturation markers. In that case, the enhanced DC maturation was associated with two- ...
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DC Maturation: A Brief Comparison between Three Different Processes
... the DC maturation process in ...migratory DC development, whereas its effect on other subtypes c (according to their localization, pheno- type, and immune function) is either redundant or even ...
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Dendritic Cells Activate and Mature after Infection with Mycobacterium tuberculosis
... infected DC to induce T cell proliferation using 5 and 6-carboxyfluorescein diacetate succinimidyl ester (CFSE) dilution technique was also ...infected DC revealed significant (p < ...immature DC ...
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Interferon γ Added During Bacillus Calmette Guerin Induced Dendritic Cell Maturation Stimulates Potent Th1 Immune Responses
... during DC maturation with ...used DC matured with BCG ...using DC matured with both BCG and ...the DC through the addition of IFN-γ during maturation better equip DC to ...
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Influence of sexual maturation status on the relationship between body adiposity indicators and age: a cross sectional study
... Different sexual maturation status are related to differ- ent times of exposure to changes in the pubertal reple- tion and spurt phase. The body fat and skinfolds tend to increase in the final stage of puberty ...
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Original Article Upregulation of cell surface estrogen receptor alpha is associated with the mitogen-activated protein kinase/extracellular signal-regulated kinase activity and promotes autophagy maturation
... tively at the maturation step, not the initial step, disrupting the maturation of autophagosomes into functional autolysosomes (i.e., significant increasing in autophagy formation and delaying in autophagy ...
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Metastable Intermediates as Stepping Stones on the Maturation Pathways of Viral Capsids
... HK97 maturation has been particularly amenable to study be- cause the procapsid can be assembled by simply expressing the gene that codes for the capsid protein, gp5 (42 kDa), with or with- out coexpression of the ...
9
'Introducing Dendritic Cells as a Novel Immune Inspired Algorithm for Anomaly Detection'
... Pre-programmed cell death, apoptosis is a vital part of the life cycle of a cell. Without it, we would not be able to control the growth of our bodies, and we would be subject to out of control tumours. On the initiation ...
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High step up interleaved dc dc converter with coupled inductor
... A diode and capacitor-based passive-clamp circuit is shown in Fig. 2. In this clamp circuit, the clamp capacitor (Cc) is discharged to the output through the secondary side inductor (L2) of the coupled-inductor boost ...
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Training Recurrent Neural Networks With the Levenberg-Marquardt Algorithm for Optimal Control of a Grid-Connected Converter
... Recent research [5] has shown that recurrent neural networks (RNNs) can be trained and used to control grid- connected converters. In [5], the RNN implemented a dynamic programming (DP) algorithm and was trained using ...
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