death receptors
Celastrol increases osteosarcoma cell lysis by γδ T cells through up-regulation of death receptors
... different receptors, only death receptors 4/5 (DR4/5) contain a functional cytoplasmatic death domain motif and are capable of delivering the apoptotic signal of TRAIL/ Apo-2L ...
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Activation of autophagic flux by epigallocatechin gallate mitigates TRAIL-induced tumor cell apoptosis via down- regulation of death receptors
... Epigallocatechin gallate (EGCG) is a major polyphenol in green tea. Recent studies have reported that EGCG can inhibit TRAIL-induced apoptosis and activate autophagic flux in cancer cells. However, the mechanism behind ...
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Accumulation of autophagosomes in breast cancer cells induces TRAIL resistance through downregulation of surface expression of death receptors 4 and 5
... Autophagosomes mediate downregulation of surface expression of TRAIL death receptors. We have previously shown that deficiency of DR4 and DR5 on the cell surface is a critical mechanism of TRAIL resistance ...
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Ethanolic extract of Descurainia sophia seeds sensitizes A549 human lung cancer cells to TRAIL cytotoxicity by upregulating death receptors
... reports have demonstrated that crude extracts or puri- fied active phytochemicals from medicinal herbs with pharmacological activity exert synergistic cytotoxicity against cancer cells when co-administered with recombin- ...
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Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post lactational regression
... between death receptor pathways and Bcl-2 regulatory factors is well established [55] and may explain the early activation of these two Bcl homo- ...encoding death receptors, and that delayed ...
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Mislocalization of death receptors correlates with cellular resistance to their cognate ligands in human breast cancer cells
... the death receptors (DRs) TNF receptor 1 (TNFR1), Fas/CD95, DR4 (TRAIL-R1) and/or DR5 (TRAIL-R2), ...the death ligands, recombinant human TNFα, FasL and TRAIL, and found a correlation with the ...
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TVB Receptors for Cytopathic and Noncytopathic Subgroups of Avian Leukosis Viruses Are Functional Death Receptors
... 18. Sakahira, H., M. Enari, and S. Nagata. 1998. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391:96–99. 19. Schulze-Osthoff, K., D. Ferrari, M. Los, S. Wesselborg, and M. E. ...
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Adenovirus mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients
... In the current paper, we performed immunoprofiling of patients participating in the 002:CD40L trial to define the mechanisms of action of AdCD40L and to find bio- markers that correlate with survival. PBMCs were puri- ...
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The role of death receptors in ER stress and Inflamation
... Here we have elucidated a key role for FADD in ER stress-induced cytokines, downstream of TRAIL receptors DR4 and DR5. However, we consistently saw that FADD ablation afforded a greater protection from ER ...
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Death receptors couple to both cell proliferation and apoptosis
... contribute to this unusual feature, since Bcl-2 does not activate cell proliferation, and it generally does not block Fas-induced death in lymphocytes. A second study exam- ined a variety of tumors and observed ...
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An NF-κB-Dependent Survival Pathway Protects against Cell Death Induced by TVB Receptors for Avian Leukosis Viruses
... TVB receptors are death receptors of the tumor necrosis factor receptor (TNFR) family and serve as cellular receptors for cytopathic subgroups B and D and noncytopathic subgroup E of the avian ...
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Willful Death (Dying before Death)
... Human is captivated by worldly belongings. When one finds a chance to, temporarily, put the chaotic world behind for moments of recollection, there comes the overpowering horror of death and what befell upon ...
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Toll like receptors: a family of pattern recognition receptors in mammals
... The Drosophila genome contains nine genes that encode Toll and related receptors (dToll1 - dToll9), whereas ten Toll-like receptor (TLR) genes have been identified in mice and humans [1-6]. The human and murine ...
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Differential trafficking of AMPA receptors following activation of NMDA receptors and mGluRs
... AMPA receptors at high Pr synapses and a compensatory increase in the surface expression of AMPA receptors at low Pr ...AMPA receptors, and also conserved the distribution of AMPA receptors ...
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Retinoic acid receptors and nuclear orphan receptors in the development of Xenopus laevis
... Int J Dev lliol 40 255 262 (\ 9%) 255 Retinoic acid receptors and nuclear orphan receptors in the development of Xenopus laevis CHRISTINE DREYER* and HEIDRUN ELLINGER ZIEGELBAUER' Max Planck Institut[.] ...
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Expression of HIV receptors, alternate receptors and co receptors on tonsillar epithelium: implications for HIV binding and primary oral infection
... HIV receptors, co-receptors, surface adhesion molecules and alternate receptors in stratified squamous epithelium and cryptal reticulated epithelium that individually or collectively could support ...
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On Defining ‘Near-Death Experience’, ‘Near-Death Memory’ and ‘Near-Death Report’
... Abstract: In 1975, the physician Raymond Moody published the bestseller Life after Life. Moody introduced the term ‘near-death experience’ in his book to describe specific experiences of people who have survived a ...
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The death of me:literature, relational death, and the human thing
... ownmost death, as for instance when he meditates escaping while wearing the prison gardeners’ ‘old blue smock embroidered in red’—the irruptive potential of the other condemned man is recognised and thus ...
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When 7 transmembrane receptors are not G protein–coupled receptors
... transmembrane receptors transduce extracellular signals by coupling to heterotrimeric G proteins, although recent in vitro studies have clearly demonstrated that they can also signal via G protein–independent ...
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Locust Wind Receptors
... Wind Pronounced Input setae pivot acceleration response response distribution None None Bilateral; all areas;diverse curvature angles + for None Unilateral; pivots into restricted optima[r] ...
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