dentate gyrus (DG)
Adult neurogenesis modifies excitability of the dentate gyrus
... Adult-born dentate granule neurons contribute to memory encoding functions of the dentate gyrus (DG) such as pattern ...adult DG neurogenesis influences local circuit activity and ...
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Rapid compensatory changes in the expression of EAAT-3 and GAT-1 transporters during seizures in cells of the CA1 and dentate gyrus
... the dentate gyrus (DG) and CA1 at different times after 4- aminopyridine (4-AP) administration because it was demonstrated that 4-AP increases the levels of glutamate and GABA in the hippocampal ...
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Santoso, Ariane (2009): Cell proliferation and cell survival in the dentate gyrus of adult mice under naturalistic conditions. Dissertation, LMU München: Fakultät für Biologie
... the dentate gyrus (DG) in the hippocampal formation, where new cells are produced that partly become functional neurons in the granule cell layer (GCL) of the DG (van Praag et ...the DG ...
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Transmembrane protein 108 involves in adult neurogenesis in the hippocampal dentate gyrus
... hippocampal dentate gyrus by using Tmem108 mutant ...the dentate gyrus and CA3 of the hippocampus. Dentate gyrus is a brain region where adult neurogenesis occurs, and aberrant ...
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Functional synaptic plasticity in the dentate gyrus of the rat hippocampus
... embedded in gelatine, were frozen and sectioned coron- ally at 40 um intervals. The animals were previously involved in electrophysiological experiments, in which stimulation of both the dorsal and the ventral regions of ...
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ApoE is required for maintenance of the dentate gyrus neural progenitor pool
... the dentate gyrus were counted (Lagace et al., 2007). For dentate gyrus volume quantification, the sections were stained with Nissl solution and estimated by Cavalieri ...
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The effect of Urtica dioica extract on the number of astrocytes in the dentate gyrus of diabetic rats
... the dentate gyrus is an important site for adult neurogenesis in mammals and neuropathological damage occurs in diabetic cases, and also because the number of astrocytes is increased in this disease, and ...
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Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus
... term memory induction in the dentate gyrus of the hippo- campus. We exposed Fvb/n mice to contextual fear condi- tioning, and checked for morphological and molecular changes in astrocytes. We found that 1 h ...
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Neurogenin 2 has an essential role in development of the dentate gyrus
... by DG progenitors (Pleasure et ...the dentate granule neuron phenotype not controlled by Ngn2, or that it takes over some of the functions of Ngn2 when this gene is ...in DG neurogenesis in a ...
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Normal And Epilepsy-Associated Pathologic Function Of The Dentate Gyrus
... electrophysiological experiments involved electrical antidromic stimulation of the hilus (to activate mossy fibers directly) and demonstrated the role of mossy fiber sprouting in elevating DGC excitability (Tauck and ...
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How to make a hippocampal dentate gyrus granule neuron
... during DG development The formation of the central nervous system (CNS) requires precise orchestration of proliferation, cell fate determination and ...the DG granule neurons, we focus our discussion on the ...
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Human UCB-MSCs treatment upon intraventricular hemorrhage contributes to attenuate hippocampal neuron loss and circuit damage through BDNF-CREB signaling
... the dentate gyrus (DG) where neurogenesis primarily occurs in the ...the dentate gyrus, indicating the neurogenic effects of hUCB-MSC ...the DG compared to control ...
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Exposure of neonatal rats to alcohol has differential effects on neuroinflammation and neuronal survival in the cerebellum and hippocampus
... 6-diamidino-2-phenylindole; DG: dentate gyrus; EGL: external granule layer; FASD: fetal alcohol spectrum disorder; GCL: granule cell layer; GFAP: glial fibrillary acidic protein; HMGB1: high mobility ...
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Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes
... 3; DG: Dentate gyrus; E/I: Excitation/ inhibition; ECF: Enhanced chemiofluorescence; GABA: γ -Aminobutyric acid; GABA(A)R: γ -Aminobutyric acid (A) receptor; GFAP: Glial fibrially acidic protein; IQ: ...
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Effects of nanoparticle zinc oxide on spatial cognition and synaptic plasticity in mice with depressive-like behaviors
... After completion of all behavioral assays, the electrophy- siological recording was measured in vivo . Synaptic responses were quantified as the field excitatory postsy- naptic potential (fEPSP) extracellularly recorded ...
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Apolipoprotein E4, inhibitory network dysfunction, and Alzheimer’s disease
... the dentate gyrus (DG) are particularly vulnerable to apoE4 fragment-mediated neurotoxicity, and in apoE4 fragment transgenic mice, knocking out tau rescues GABAergic interneuron loss as well as ...
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The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation
... hippocampus, dentate gyrus (DG) and ...the DG and hippocampus ...the DG was persistently negatively affected after irradiation, particularly at ...
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Search | Preprints
... on dentate gyrus (DG) granule cell neurons (GCNs) were performed in acute brain slices from controls and methamphetamine experienced male and female rats and neuronal excitability were evaluated from ...
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Anti-inflammatory/anti-amyloidogenic effects of plasmalogens in lipopolysaccharide-induced neuroinflammation in adult mice
... As shown in Figure 4A, the dentate gyrus (DG) of the hippocampus also demonstrated LPS-induced increases in the number and intensity of immunostaining for Iba- 1 in microglia (d) and GFA[r] ...
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Pentraxin 3 mediates neurogenesis and angiogenesis after cerebral ischaemia
... Methods: PTX3 knockout (KO) or wild-type (WT) mice were subjected to experimental cerebral ischaemia (induced by middle cerebral artery occlusion (MCAo)). Poststroke neurogenesis was assessed by nestin, doublecortin ...
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