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Development of cerebral cortex

Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development

Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development

... a cortex-specific Dicer mutant in which Dicer is deleted before the onset of ...throughout development, at the expense of upper layer neurons, which are almost completely ...the cerebral ...

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Genetic influences on thinning of the cerebral cortex during development.

Genetic influences on thinning of the cerebral cortex during development.

... the cerebral cortex, and has an important role during brain development and in synaptic plasticity (Cohen-Cory et ...the cortex (Webster et ...

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Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex

Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex

... the development of cerebral ...of cerebral cortex from embryonic day (E) ...in development of cerebral cortex through regulating radial glial scaffolds of RGCs to control ...

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Development of the Fetal Cerebral Cortex in the Second Trimester: Assessment with 7T Postmortem MR Imaging

Development of the Fetal Cerebral Cortex in the Second Trimester: Assessment with 7T Postmortem MR Imaging

... The second trimester is the most important phase, during which most sulci are present and can be clearly shown on 7T postmor- tem MR imaging. Perhaps the specific time during which neuro- pathologic features of sulci ...

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Development of the cerebral cortex: Emx genes and interneuron migration

Development of the cerebral cortex: Emx genes and interneuron migration

... Confocal images of each hemisphere of each slice were analysed, and the number of Dil labelled cells in each layer of the developing cortex, the VZ, the IZ, the CP, and the MZ were counted (Fig. 4.9A,B). In these ...

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Par complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex

Par complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex

... During development of the mouse cerebral cortex, ventricular zone (VZ) progenitors, neuroepithelial and radial glial cells, enlarge the progenitor pool by proliferative divisions, while basal ...

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Differential Expression of mGluR2 in the Developing Cerebral Cortex of the Mouse

Differential Expression of mGluR2 in the Developing Cerebral Cortex of the Mouse

... Glutamatergic synaptic transmission is an essential component of neural circuits in the central nervous system. Glutamate exerts its effects by binding to various types of glutamate receptors, which are found distributed ...

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Analysis of the Cerebral Cortex in Holoprosencephaly with Attention to the Sylvian Fissures

Analysis of the Cerebral Cortex in Holoprosencephaly with Attention to the Sylvian Fissures

... cortical development (17), and it would not be surprising if some of these were affected in ...the development of too few white matter tracts in these patients as a result of the profoundly disturbed brain ...

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Pancortins interact with amyloid precursor protein and modulate cortical cell migration

Pancortins interact with amyloid precursor protein and modulate cortical cell migration

... Neuronal precursor cell migration in the developing mammalian brain is a complex process requiring the coordinated interaction of numerous proteins. We have recently shown that amyloid precursor protein (APP) plays a ...

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Akirin2 is essential for the formation of the cerebral cortex

Akirin2 is essential for the formation of the cerebral cortex

... The cerebral cortex is a uniquely mammalian structure that is the site of consciousness and higher cognitive func- tions such as language, memory, and ...the cortex is a hallmark of human evolution: ...

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EFFECT OF LEVETIRACETAM ON THE CEREBRAL CORTEX OF NEWBORN RAT

EFFECT OF LEVETIRACETAM ON THE CEREBRAL CORTEX OF NEWBORN RAT

... the development of embryo nervous system after maternal exposure during pregnancy has not been ...developing cerebral cortex ...the cerebral cortex defects in the cerebrum of the ...

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Cortical development: the art of generating cell diversity

Cortical development: the art of generating cell diversity

... the cerebral cortex in phylogeny even across cortical areas (Winfield et ...the cortex that specialize in specific aspects of information ...occipital cortex comprises the visual areas, with ...

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Selective vulnerability to kainate-induced oxidative damage in different rat brain regions

Selective vulnerability to kainate-induced oxidative damage in different rat brain regions

... (hippocampus, cerebral cortex, striatum, hypothalamus, amygdala/piriform cortex and cerebellum) after the systemic administration of an excitotoxic dose of kainic acid (KA, 9 mg/kg, ...

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Study of brain morphology change in Alzheimer’s disease and amnestic mild cognitive impairment compared with normal controls

Study of brain morphology change in Alzheimer’s disease and amnestic mild cognitive impairment compared with normal controls

... results were similar to those, compared with the NC group, the cortical thickness and surface area in the right hemi- sphere of patients with aMCI had no significant difference; only a slight atrophy in the lateral ...

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Progressive brain failure after diffuse hypoxic ischemic brain injury: a serial MR and proton MR spectroscopic study

Progressive brain failure after diffuse hypoxic ischemic brain injury: a serial MR and proton MR spectroscopic study

... case makes it likely that all cortical layers were dam- aged. More evident are the differences in susceptibil- ity between neurons of the phylogenetically older portions of the nervous system and the newer por- tions, ...

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PET Imaging with [18F]FSPG Evidences the Role of System xc- on Brain Inflammation Following Cerebral Ischemia in Rats

PET Imaging with [18F]FSPG Evidences the Role of System xc- on Brain Inflammation Following Cerebral Ischemia in Rats

... following cerebral ischemia and after treatment were averaged and compared with the averaged baseline control values (day 0) and non-treated ischemic rats respectively using one-way ANOVA followed by Dunnet’s ...

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DEVELOPMENTAL NEUROPATHOLOGY OF PERINATAL BRAIN DAMAGE AND THE PATHOGENESIS OF EPILEPSY

DEVELOPMENTAL NEUROPATHOLOGY OF PERINATAL BRAIN DAMAGE AND THE PATHOGENESIS OF EPILEPSY

... the cortex intrinsic capillaries and may respond inadequately to local functional demands ...the cortex surface and/or within the meningeal space (Figure ...

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Multi-detector CT angiography in intracranial dural AV fistula at the foramen magnum

Multi-detector CT angiography in intracranial dural AV fistula at the foramen magnum

... entorhinal cortex, and cere- bral cortex after controlling for age at death, sex, CDR (making the subjects who died at different stages of the disease compara- ble), body mass index (BMI; measured by the ...

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Computations in the deep vs superficial layers of the cerebral cortex

Computations in the deep vs superficial layers of the cerebral cortex

... the cerebral neocortex, which involve feedforward operations to form non-linear combinations of the inputs from previous cortical areas utilizing the convergence from stage to stage to construct useful ...

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Morphometric characterization of microglial phenotypes in human cerebral cortex

Morphometric characterization of microglial phenotypes in human cerebral cortex

... As mentioned above, IBA1-IR cells present in the mouse cingulate cortex were generally highly branched, and their cell bodies were evenly distributed in the tissue. The densely packed arborizations extended by ...

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