Diagnostics and Therapeutics
Liver Abscesses: What Diagnostics and Therapeutics in the Kati Reference Health Center (Mali)?
... K., Traore, A., Koné, A., Konate, M., Tounkara, I., Keita, M.A., Traore, I., Togo- la, M., Tall, F.K., Diallo, D., Magane, M.I., Sanogo, D.S., Koné, A., Diakite, I., Traore, A. and Togo, A. (2018) Liver Abscesses: What ...
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Emerging Implications of Nanotechnology on Cancer Diagnostics and Therapeutics
... and therapeutics [1] This progress very likely will have important implications for management of the cancer patient in the near ...cancer diagnostics and ...
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Developing Peptide Based Capture Agents for Diagnostics and Therapeutics
... To address the high demand for protein detection agents with antibody like sensitivity in diagnostics platforms while overcoming the inherent disadvantages of antibodies, scientists have tried to develop ...
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Neurology in the 21st Century: Contemporary state of Diagnostics and Therapeutics
... Although neurological disease has been recognized since antiquity, neurology as a systematic clinical discipline is less than 130 years old. Neurological practice has traditionally been constrained by the complexity of ...
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Priming nanoparticle-guided diagnostics and therapeutics towards human organs-on-chips microphysiological system
... unclear pharmacokinetics (PK) of NPs in terms of the nanotoxicity and absorption, distribution, metabolism, and excretion (ADME) profiles [5]. To validate PK pro- files of NPs, animal models (mostly rodent surrogates) ...
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System To Assess Genome Sequencing Needs for Viral Protein Diagnostics and Therapeutics
... SARS and, to a lesser extent, Ebola Zaire are outliers be- cause there was no near-neighbor sequence data in GenBank at the time of our analyses to narrow the list of protein or DNA signature candidates. Most of the ...
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Biopolymer Nanoparticles: A Review of Prospects for Application as Carrier for Therapeutics and Diagnostics
... Biopolymer nanoparticles are molecules of interest in the direction of generation of new pre-diagnostic and treatment strategies with improved efficacy and specificity. Several methods have been developed to produce ...
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Progress and problems in the biology, diagnostics, and therapeutics of prion diseases
... The term “prion” was introduced by Stanley Prusiner in 1982 to describe the atypical infec- tious agent that causes transmissible spongiform encephalopathies, a group of infectious neurodegenerative diseases that include ...
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Role of Extracellular Vesicles in Viral and Bacterial Infections: Pathogenesis, Diagnostics, and Therapeutics
... Notably, EVs derived from cells infected with either viral or bacterial pathogens demonstrate several mechanisms to mediate the immune system, including effects to inhibit host EV ef[r] ...
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Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics
... especially in the diagnostics of cancer. Literature has already hypothesized the interaction of CTX and MMP- 2, a protein highly upregulated during tumor production. Therefore, understanding the mechanism by which ...
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Nucleic Acid Aptamer-Guided Cancer Therapeutics and Diagnostics: the Next Generation of Cancer Medicine
... erential accumulation of nano-sized anti-tumor agents in tumors [66]. Based on the EPR effect, a passive tu- mor-targeting strategy has improved patient compli- ance and reduced adverse effects over the conven- tional ...
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Aptamers in the Therapeutics and Diagnostics Pipelines
... sensitivity and 94.1% specificity when evaluated in serum samples of TB subjects and healthy volunteers, while the CE15 aptamer had relatively lower sensitivity (89.6%) and comparable specificity (94.1%) [132]. These ...
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The human proteome – a scientific opportunity for transforming diagnostics, therapeutics, and healthcare
... panion diagnostics (issued 12 July 2011) and for research-only or investigation-only (RUO and IUO) pro- ducts (issued 1 June 2011), as well as several IVDs cleared by the FDA for leukemia, breast, ovarian, pros- ...
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Nanotechnology, from quantum mechanical calculations up to drug delivery
... The International Journal of Nanomedicine is an international, peer- reviewed journal focusing on the application of nanotechnology in diagnostics, therapeutics, and drug d[r] ...
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Diet-Induced Rat Model of Gradual Development of Non-Alcoholic Fatty Liver Disease (NAFLD) with Lipopolysaccharides (LPS) Secretion
... developed a HFHCh diet rat model of NASH in which 2 weeks of dietary intervention induced fat accumulation and lobular inflammation, while 14 weeks of the diet was associated with balloo[r] ...
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Overall Survival and Adjuvant Therapy in Women with Ovarian Carcinosarcoma: A Single-Institution Experience
... A similarly sized cohort treated at Memorial Sloan-Kettering Cancer Center found that treatment with carboplatin / taxol may be a suitable first-line chemotherapy regimen with a median s[r] ...
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Consolato M. Sergi 1,2
... 22. Rodriguez-Gonzalez, M.; Perez-Reviriego, A.A.; Castellano-Martinez, A.; Lubian-Lopez, S.; Benavente-Fernandez, I. Left Ventricular Dysfunction and Plasmatic NT-proBNP Are Associated with Adverse Evolution in ...
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Protein Carbonyl Content Is a Predictive Biomarker of Eccentric Left Ventricular Hypertrophy in Hemodialysis Patients
... CRP: C-reactive protein; IDWG: interdialytic weight gain; NG: normal left ventricle geometry; CR: concentric remodeling; cLVH: concentric left ventricular hypertrophy; eLVH: eccentric [r] ...
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Two Potential Clinical Applications of Origami-Based Paper Devices
... To use this device, we sequentially folded each of two separate reagent zones, one preloaded with NaOH and one preloaded with ascorbic acid (AA), over the central test zone, and added 8 [r] ...
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Rapid Extraction Method of Mycobacterium ulcerans DNA from Clinical Samples of Suspected Buruli Ulcer Patients
... Abstract: Isothermal amplification techniques such as recombinase polymerase amplification (RPA) and loop-mediated isothermal amplification (LAMP) for diagnosing Buruli ulcer, a necrotic[r] ...
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