Distal colon
Unanticipated stimulatory action of glucocorticoids on epithelial calcium absorption Effect of dexamethasone on rat distal colon
... We studied the action of a glucocorticoid (GC, dexamethasone) and 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] on transepithelial calcium (Ca) transport in rat distal colon. GC 1.2 mg or 1,25(OH)2D3 270 ng were ...
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Characterization of aldosterone induced potassium secretion in rat distal colon
... rat distal colon was investigated by measuring mucosal-to-serosal (Jms) and serosal-to-mucosal (Jsm) 42K fluxes ...rat distal colon contains apical TEA- and Ba-sensitive K channels; (b) ...
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Increased wall thickness using ultrasonography is associated with inflammation in an animal model of experimental colitis
... In conclusion, increased intestinal wall thickness in response to DSS- or TNBS-induced colitis was able to be visualized by transabdominal bowel ultrasound in rats using a clinical scanner. TNF- α increased significantly ...
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Functional expression and segmental localization of rat colonic K adenosine triphosphatase
... A putative cDNA for the colonic K-ATPase has recently been cloned (Crowson, M.S., and G. E. Shull. 1992. J. Biol. Chem. 267:13740-13748). Considerable evidence exists that there are two K-ATPases and active K absorptive ...
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Role of oxidative stress in oxaliplatin-induced enteric neuropathy and colonic dysmotility in mice
... Signalling Technologies, MA, USA) overnight at 4°C. Tissues were then washed in PBS (3 × 10 min) before incubation with species-specific secondary antibodies labelled with different fluorophores: donkey anti-chicken Alexa ...
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Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat
... The role of BDNF in regulating visceral sensitivity has been suggested by a previous study showing that intra- peritoneal injection of BDNF neutralizing antibody attenuates colonic inflammation-induced colonic hyper- ...
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Session 1: colonic physiology
... and distal (sigmoid and descending) colon, but may be more extensive and cause a ...human distal colon was characterized by mainly electrogenic Na + absorption, a lumen-negative transmucosal ...
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IL 22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis
... proximal colon (just below the ileocecal junction) of TCRαKO mice selected for the presence of severe colitis as defined by enlarged colonic diameter, as previously described (28) (Figure ...proximal colon ...
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STUDIES OF DISTAL COLONIC MOTILITY IN CHILDREN
... These data show characteristic and different patterns in closely related seg- ments of the distal colon, with a tendency to broader wave forms in the lower rectum. The possible physiolog[r] ...
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Expression of miRNA in different regions of the colon: An investigation in Zucker(fa/fa) rats
... of colon carcinogenesis is more effective in retarding the growth of distal developing ...in distal colon and tumors whereas has an opposite effect on the ACF or tumors developing in the ...
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Original Article Effects of selective antagonism of β-adrenoceptor sub-types on motility to noradrenalin in rat colon
... Tissue was harvested from the mucosa of rat distal colon, washed with PBS, and homoge- nized in 300 μl cold lysis buffer, pH 7.5, con- taining Nonidet P-40 (1%), TRIS-HCl (10 mM, pH 8.0), EDTA (1.0 mM), ...
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A shift from distal to proximal neoplasia in the colon: a decade of polyps and CRC in Italy
... the distal colon and rectum ...the colon thus offers potential implications as regards screening and control of subjects at ...the colon segments, attributed by the authors to the age of the ...
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Influence of MSI and 18q LOH markers on capecitabine adjuvant monotherapy in colon cancer patients
... (P=0.004). Distal colon cancers with 18q LOH have a greater survival rate when treated with capecitabine than patients with stable tumors ...of colon cancer patients eligible for capecitabine ...
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SLC26A3 inhibitor identified in small molecule screen blocks colonic fluid absorption and reduces constipation
... SLC26A3 loss of function in humans or KO mice produces CLD with marked diarrhea, whereas the inhib- itor studied here had only partial efficacy in a mouse model of constipation. This difference could be due to partial ...
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Large bowel obstruction secondary to gallstone impaction at a sigmoid diverticular stricture: the radiological features
... Intestinal obstruction secondary to displacement of a stone from the gall bladder into the intestinal tract is relatively uncommon. The commonest site of calculus impaction is at the ilio- caecal valve. Occasionally, ...
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Regulation of cation transport by low doses of glucocorticoids in in vivo adrenalectomized rat colon
... dexamethasone levels that saturate the glucocorticoid receptor but also bind to greater than 35% of aldosterone receptors. Saturation of the pure glucocorticoid response occurred in both segments with RU26988, a ...
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Transverse colon volvulus in a 15 year old boy and the review of the literature
... transverse colon with a cut-off near the splenic ...descending colon [Fig ...transverse colon volvulus [Fig 4] rotated in a three hun- dred and sixty degrees clockwise ...transverse colon was ...
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Hormone therapy in relation to survival from large bowel cancer.
... proximal colon cancer cases, an increased risk of mortality was associated with increasing duration of HT use compared to HT non-users ...among distal colon ...
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Electrogenic sodium absorption in rabbit cecum in vitro
... physiological and pathophysiological implications. However, only limited studies have been performed in cecum, which comprises 50% of the macrosurface of the rabbit colon. In vitro under short-circuit conditions, ...
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COMPARISON OF RECTOSIGMOID MOTILITY IN NORMAL CHILDREN, CHILDREN WITH RECURRENT ABDOMINAL PAIN, AND CHILDREN WITH ULCERATIVE COLITIS
... man colonic motility : a comparative study of normal subjects, patients with ulcerative colitis, and patients with the irritable colon syndrome. Z.: Studies in distal colonic[r] ...
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