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Dried Blood Spot (DBS)

Evaluation of dried blood spot technique for pharmacokinetic study of hydrochlorothiazide andcomparison of human plasma versus dried blood spot.

Evaluation of dried blood spot technique for pharmacokinetic study of hydrochlorothiazide andcomparison of human plasma versus dried blood spot.

... Background: The dried blood spot (DBS) technique is a convenient alternative sample collection method to venipuncture. The use of DBS was fi rst widely introduced in the 1960’s by Dr. Guthrie to ...

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A Review On Dried Blood Spot Analysis

A Review On Dried Blood Spot Analysis

... of blood was wiped and discarded; after that, the blood was dropped directly onto a Whatman FTA DMPK-C paper card (GE Healthcare, the ...Venous dried blood spot (VDBS) samples were ...

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Agreement between measurement of 25-hydroxyvitamin D3 in dried blood spot samples and serum in a Chinese population in the Netherlands

Agreement between measurement of 25-hydroxyvitamin D3 in dried blood spot samples and serum in a Chinese population in the Netherlands

... the Dried Blood Spot Laboratory (DBSL, Geleen, the ...DBS blood from the participants. Using single-use lancets, a drop of blood was formed and allowed to drop freely onto the fi lter ...

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Plasmodium falciparum HRP2 ELISA for analysis of dried blood spot samples in rural Zambia

Plasmodium falciparum HRP2 ELISA for analysis of dried blood spot samples in rural Zambia

... ROC curves are used as a metric to determine the sen- sitivity and specificity of a diagnostic assay as compared to the chosen gold standard. An ideal ROC curve forms a 90º angle in the left corner of the graph, which ...

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Field Evaluation of a Broadly Sensitive HIV 1 In House Genotyping Assay for Use with both Plasma and Dried Blood Spot Specimens in a Resource Limited Country

Field Evaluation of a Broadly Sensitive HIV 1 In House Genotyping Assay for Use with both Plasma and Dried Blood Spot Specimens in a Resource Limited Country

... and dried blood spot (DBS) samples with a median viral load (VL) of 58,187 copies/ml, ranging from 253 to 3,264,850 against the commercial assay ...

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 DEVELOPMENT AND VALIDATION OF METHAMPHETAMINE ANALYSIS METHODS IN DRIED BLOOD SPOT SAMPLE USING GAS CHROMATOGRAPHY – MASS SPECTROMETRY

 DEVELOPMENT AND VALIDATION OF METHAMPHETAMINE ANALYSIS METHODS IN DRIED BLOOD SPOT SAMPLE USING GAS CHROMATOGRAPHY – MASS SPECTROMETRY

... Methamphetamine or known as sabu is one of the amphetamine groups that give a very strong central nervous system stimulant effect. Nowadays, the method used to test the specimens to prove a person who had ...

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The Use of Dried Blood Spot Samples in Screening Drugs of Abuse

The Use of Dried Blood Spot Samples in Screening Drugs of Abuse

... collecting blood as vaccume tubes or capillary pipettes ...of dried blood spots in screen- ing drug of abuse is the naive area of ...of dried blood spot for drug analysis. Use of ...

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A Simple and Cost-Effective Freeze-Thaw Based Method for Plasmodium DNA Extraction from Dried Blood Spot

A Simple and Cost-Effective Freeze-Thaw Based Method for Plasmodium DNA Extraction from Dried Blood Spot

... The dried blood spot was prepared using 25µl of parasitized blood and spreading it in circular manner. It was allowed to dry for 8 h at room temperature. Six punches of DBS (3mm in diameter) ...

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Use of dried blood spot specimens in the detection of human immunodeficiency virus type 1 by the polymerase chain reaction

Use of dried blood spot specimens in the detection of human immunodeficiency virus type 1 by the polymerase chain reaction

... Use of Dried Blood Spot Specimens in the Detection of Human Immunodeficiency Virus Type 1 by the Polymerase Chain Reaction SHARON CASSOL,1* TERESA SALAS,1 MAX ARELLA,2 PETER NEUMANN,' MA[r] ...

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Metronidazole Population Pharmacokinetics in Preterm Neonates Using Dried Blood-Spot Sampling

Metronidazole Population Pharmacokinetics in Preterm Neonates Using Dried Blood-Spot Sampling

... tify covariates that explain the phar- macokinetic variability observed in these neonates. We also believe this to be the first reported pharmacokinetic study in which all investigations were performed with dried ...

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Capillary microsampling of mouse blood in pre-clinical studies: an alternative to dried blood spot sampling.

Capillary microsampling of mouse blood in pre-clinical studies: an alternative to dried blood spot sampling.

... [8]. Blood spot size varies with viscosity so a higher haematocrit value will reduce the spread of the blood on the card, a disk of the same size can therefore contain variable amounts of matrix and ...

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Confirmation of HCV viremia using HCV RNA and core antigen testing on dried blood spot in HIV infected peoples who inject drugs in Vietnam

Confirmation of HCV viremia using HCV RNA and core antigen testing on dried blood spot in HIV infected peoples who inject drugs in Vietnam

... (www.hcv.lanl.gov). Blood samples from HCV infected outpatients followed in the Montpellier University hos- pital and having provided informed consent were used for the validation of PCR and HCVcAg methods on DBS ...

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Dynamic and temporal assessment of human dried blood spot MS/MSALL shotgun lipidomics analysis

Dynamic and temporal assessment of human dried blood spot MS/MSALL shotgun lipidomics analysis

... other blood matrices, four blood matrices were assessed in this study: 1) whole blood (venous drawn), 2) plasma, 3) serum, and 4) finger pricked blood, the direct ...different blood ...

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A pilot screening of high-risk Gaucher disease children using dried blood spot methods in Shandong province of China

A pilot screening of high-risk Gaucher disease children using dried blood spot methods in Shandong province of China

... Considering the operation difficulty, the diagnostic algorithm proposed by Maja et al. [15] might not be suitable for the national conditions of China since exam- inations for serum ferritin levels or tartrate resistant ...

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A dried blood spot mass spectrometry metabolomic approach for rapid breast cancer detection

A dried blood spot mass spectrometry metabolomic approach for rapid breast cancer detection

... were dried by pure nitrogen gas flow at 50 ° C. Dried samples were derivatized at 65 ° C for 20 minutes using 60 μ L acetyl chloride/1-butanol (10:90, v/v) ...were dried again as mentioned earlier. ...

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Use of Dried Blood Spot to Improve the Diagnosis and Management of HIV in Resource Limited Settings

Use of Dried Blood Spot to Improve the Diagnosis and Management of HIV in Resource Limited Settings

... of blood in the tubes for testing HIV infec- ...of blood col- lected available for testing, and the difficulties encountered in laboratories to extract the maximum possibilities without material ...

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Field Study of Dried Blood Spot Specimens for HIV 1 Drug Resistance Genotyping

Field Study of Dried Blood Spot Specimens for HIV 1 Drug Resistance Genotyping

... airfreight items under the same environmental conditions as pas- senger luggage. The maximum temperature reached was 40°C, which occurred during a layover in Dubai between flights, while the minimum temperature was 1°C. ...

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Diagnosis of congenital CMV infection via DBS samples testing and neonatal hearing screening: an observational study in Italy

Diagnosis of congenital CMV infection via DBS samples testing and neonatal hearing screening: an observational study in Italy

... The diagnosis of cCMV infection can be achieved by the examination of salivary/urinary samples collected within the first 2–3 weeks of age as the results of NHSP [3–6]; after this early period of life, it is possible to ...

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Rubella sero-prevalence among children in Kilimanjaro region: a community based study prior to the introduction of rubella vaccine in Tanzania

Rubella sero-prevalence among children in Kilimanjaro region: a community based study prior to the introduction of rubella vaccine in Tanzania

... Background: Childhood rubella infection is a mild, self-limiting illness. Rubella infection among pregnant women however, is a major public health concern. Depending on gestation age, it may result in fetal death, ...

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Trace 56Fe, 63/65Cu and 64Zn metal analysis in whole blood by SEC HPLC ICPMS

Trace 56Fe, 63/65Cu and 64Zn metal analysis in whole blood by SEC HPLC ICPMS

... in blood and utilised dried blood spot sampling (DBS) ...technology. Blood was taken from one female subject and extraction conditions were ...the blood samples separated via ...

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