DSS induced colitis
rSj16 Protects against DSS-Induced Colitis by Inhibiting the PPAR-α Signaling Pathway
... be induced by Chil1 and Chil3 [12, ...on DSS-induced colitis in mice were associated with the ability of rSj16 to regulate the production of inflammatory mediators and ...
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Intestinal Epithelial Cell-Specific Deletion of PLD2 Alleviates DSS-Induced Colitis by Regulating Occludin
... of colitis, and improved the survival rate of the ...with colitis 50, 51 ; combining this therapy with the conventional immunosuppressant agents may be a promising ...in DSS-induced ...of ...
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Exosomes released by granulocytic myeloid-derived suppressor cells attenuate DSS-induced colitis in mice
... To demonstrate the immunosuppressive effect of G-MDSC exo, we observed the roles of G-MDSC exo on CD4 + T cell proliferation and Tregs expansion in vitro. We found that G-MDSC exo could inhibit CD4 + T cell proliferation ...
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Anti-inflammatory effects of Lactobacillus casei BL23 producing or not a manganese-dependant catalase on DSS-induced colitis in mice
... a DSS-induced colitis ...TNBS-induced colitis [43] and previous ones obtained with other ...a DSS-induced [29,30] and TNBS-induced [44] colitis model, ...two ...
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Cyclic nigerosylnigerose ameliorates DSS-induced colitis with restoration of goblet cell number and increase in IgA reactivity against gut microbiota in mice
... ratio induced by CNN ...the DSS-induced loss of goblet cells by CNN ...cells induced by CNN treatment might contribute to the formation of a complex of IgA, mucus, and microbiota, which ...
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Fermented barley and soybean (BS) mixture enhances intestinal barrier function in dextran sulfate sodium (DSS) induced colitis mouse model
... of DSS-induced colitis in mice To evaluate the therapeutic effect of BS on DSS-induced colitis, we investigated the ability of BS to ameliorate DSS-induced ...
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SRC-3 protects intestine from DSS-induced colitis by inhibiting inflammation and promoting goblet cell differentiation through enhancement of KLF4 expression
... (DSS)-induced colitis compared with wild-type mice after oral administration of 2% DSS dissolved in drinking ...2% DSS, SRC-3 -/- mice displayed higher mortality rate, significant body ...
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STAT3 Signalling via the IL-6ST/gp130 Cytokine Receptor Promotes Epithelial Integrity and Intestinal Barrier Function during DSS-Induced Colitis
... including colitis-associated CRC and gastric cancer ...during DSS-induced colitis are yet to be ...acute colitis injury through the modulation of intestinal barrier ...
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TREM-1-dependent M1 macrophage polarization restores intestinal epithelium damaged by DSS-induced colitis by activating IL-22-producing innate lymphoid cells
... microbial- induced sepsis, liver abscesses, and lupus [7, 8, 34, ...of DSS-induced colitis, which are observed in the specific TREM-1 KO mouse lines from two different ...
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Oral administration of taheebo (Tabebuia avellanedae Lorentz ex Griseb ) water extract prevents DSS induced colitis in mice by up regulating type II T helper immune responses
... experimental colitis in mice. To test this hypothesis, we adopted a method for DSS-induced colitis, as described in the Methods ...3% DSS plus TWE or 3% DSS without TWE in their ...
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Processed coffee alleviates DSS-induced colitis in mice
... l/ml (vol/vol), and the IC50 for IL-1 was significantly lower (0.63 l/ml). At the concentration used we found that coffee was not cytotoxic for the cells (data not shown). The production of IL-1 in macrophages is ...
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KARANJIN AMELIORATE DSS INDUCED COLITIS IN C57BL/6 MICE
... Activated neutrophils produce reactive oxygen and nitrogen species which induces oxidative stress, and plays a significant role in the pathogenesis of IBD. 26 Inflammaogenic reactive oxygen metabolites includes hydrogen ...
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Bifidobacterium infantisstrains with and without a combination of Oligofructose and Inulin (OFI) attenuate inflammation in DSS-induced colitis in rats
... characteristics that may also benefit adult mucosa that is under inflammatory stress. Both bacteria as well as the fiber component were effective in reducing colonic disease activity index, although DSM 15159 seemed ...
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<p>Krill Oil-Incorporated Liposomes As An Effective Nanovehicle To Ameliorate The Inflammatory Responses Of DSS-Induced Colitis</p>
... The systemic levels of endotoxins (eg, LPS), which contribute to the in fl ammatory cascade in IBD patients, 41 are positively correlated with clinical activity of UC. 31 Here, we show that KO liposomes can potently ...
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Protective effect of TSLP delivered at the gut mucosa level by recombinant lactic acid bacteria in DSS-induced colitis mouse model
... In order to study the role of TSLP in mucosal inflamma- tion we constructed a strain of L. lactis secreting TSLP (LL-TSLP). To this end, we cloned the tslp gene in the plasmid pLB333 carrying the SICE system, composed of ...
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Regulatory effects of glycyrrhizae radix extract on DSS induced ulcerative colitis
... (DSS)-induced colitis is a suitable mice model characterized by the morphologic- ally and ...biochemically. DSS induces bloody stools, ulcerations, epithelial injury and infiltration of ...
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Research Article Protective Effect of the Abelmoschus manihot Flower Extract on DSS-Induced Ulcerative Colitis in Mice
... in DSS-induced ...alleviate DSS-induced ...in DSS-induced UC mice, sug- gesting that AM could downregulate β-arrestin1 expression and interrupt NLRP3 signaling pathway ...
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Ursolic Acid Exhibits Protective Property against DSS-induced Ulcerative Colitis in Mice through STAT3 Signaling Pathway
... of DSS- induced colitis that is a commonly used model for the inflammation component of ...IBD. Colitis was charac- terized by weight loss, increased disease activity in- dex, shortened colon ...
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MALT1 inhibitors prevent the development of DSS-induced experimental colitis in mice via inhibiting NF-κB and NLRP3 inflammasome activation
... The underlying mechanisms for the protective effect of MALT1 inhibitors in DSS- induced colitis may be attributed to its inhibition on NF-κB and NLRP3 inflammasome activation in macrophages. The in ...
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MicroRNA-146a constrains multiple parameters of intestinal immunity and increases susceptibility to DSS colitis
... miR-146a-/- mice displayed an altered microbiota and, surprisingly, were more protected from DSS-induced colitis compared to their WT counterparts. In vivo bone marrow reconstitutions demonstrated a ...
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