E-cadherin
E Cadherin Dysfunction and Cancer
... development, E-cadherin dysfunction influence in premature lethality or epidermal barrier and im- munity ...role, E-cadherin is a guiding molecule in collective cell migration increasing the ...
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E cadherin expression in primary carcinomas of the breast and its distant metastases
... E-cadherin expression was interpreted as either normal (strong) or aberrant (reduced or absent) [29]. Internal pos- itive controls, such as benign breast lobules and ducts, were present in most cases. ...
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E-cadherin is Required for the Homeostasis of Lgr5+ Gastric Antral Stem Cells
... that E-cadherin is implicated in maintaining stem cell homeostasis ...ovary, E-cadherin-mediated cell adhesion is required for anchoring germline stem cells to their niche ...of ...
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The Value of Expression of E-Cadherin and VEGF Immunohistochemical Markers in Prostate Carcinomas
... the E-cadherin in suppressing the invading tumor in the cultured ...of E-cadherin permissible cell adhesion has been a prerequisite for the development of tumor or if it has been the result of ...
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Inhibition of mTORC1 induces loss of E-cadherin through AKT/GSK-3β signaling-mediated upregulation of E-cadherin repressor complexes in non-small cell lung cancer cells
... of E-cadherin repressor complexes. Among the cells expressing E-cadherin that were evaluated in this study (A549, H596, H1650, and H2009), A549 cells showed the most prominent morpho- logic ...
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Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer
... It is known that gene expression and the activation of signaling pathways are both subjected to epigenetic regulation. Many histone methyltransferases such as EZH2 and G9a have been reported to participate in can- cer ...
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E-cadherin downregulation sensitizes PTEN -mutant tumors to PI3Kβ silencing
... low E-cadherin expression are necessary for PI3Kβ ...of E-cadherin expression coincides with N-cadherin ...show E-cadherin loss and express mutant ...
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Original Article Role of cd56 and e-cadherin expression in the differential diagnosis of papillary thyroid carcinoma and suspected follicular-patterned lesions of the thyroid: the prognostic importance of e-cadherin
... in E-cadherin expression in PTC com- pared to the surrounding thyroid tissue of FA and PTC [1, ...HBME-1, E-cadherin, and CD56 might be considered helpful along with the morphological findings ...
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The E-cadherin repressor slug and progression of human extrahepatic hilar cholangiocarcinoma
... reduced E-cadherin ...of E-cadherin in human EHC tissue, as well as in cultured EHC ...of E-cadherin expression in esophageal adenocarcinoma ...that E-cadherin ...
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E-cadherin roles in animal biology: A perspective on thyroid hormone-influence
... partners. E-cadherin trans-interaction triggers activation of the phosphatidylinositol-3-kinase (PI3K) – Akt – protein kinase B pathway bound to β -catenin, generating ...
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A Study of Expression of E Cadherin and Vimentin in Oral Squamous Cell Carcinoma
... The end point of advanced cancer being distant metastasis has been the cause of death in most cases. 34 Multiple steps are hypothesised in the process of tumor metastasis all of which are required to achieve tumor ...
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RARγ-induced E-cadherin downregulation promotes hepatocellular carcinoma invasion and metastasis
... of E-cadherin, a single-span trans- membrane glycoprotein located primarily within adherent junction, is a fundamental feature of EMT [8, ...of E-cadherin correlates with poorer survival for ...
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Expression of E-Cadherin, Cytokeratin-14 and Cytokeratin-19 in tooth germ and Ameloblastoma
... of E-Cadherin, Cytokeratin-14 and Cytokeratin-19 in tooth germ and ameloblastoma” was done in the Department of Oral Pathology and Microbiology, Tamil Nadu Government Dental College and Hospital, ...
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Detection of promoter hypermethylation of the CpG island of E-cadherin in gastric cardiac adenocarcinoma
... anti- E-cadherin antibody (1 : 100 dilution in phosphate buffered saline, Santa cruz, sc-8426) overnight at 4 °C, biotinylated secondary antibody for 30 min at 37 °C and ABC reagent for 45 min at 37 ...
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E-Cadherin as a Marker for Nodal Metastasis in Head and Neck Squamous Cell Carcinoma
... the cadherin molecules especially the E- ...the E- cadherin gene is linked with poorly differentiated type of cancers, invasion and metastasis in a range of various kinds of ...
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Loss of E cadherin provides tolerance to centrosome amplification in epithelial cancer cells
... of E-cadherin expression, leading to basal levels of clustering <10%, the lowest we observed ...5, E and F; and ...pressing E-cadherin ( ∼ 100%) compared with DCB-treated cells ...
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Prognostic Value of Lymphocyte Vascular Density and E Cadherin in Inflammatory Breast Cancer
... express E-cadherin while invading in a collective manner with motile cells being at- tached to one another ...of E-cadherin and MUC1, findings that were reflected in actual cases of human ...
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Calcium binding protects E-cadherin from cleavage by Helicobacter pylori HtrA
... the E-cadherin complex in gastric epi- thelial cell lines leading to severe alterations in epithelial polarity ...cleaves E-cadherin on gastric epithelial cells, thereby opening adherence ...
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Tumor suppressor gene E-cadherin and its role in normal and malignant cells
... the E-cadherin gene in human ...of E-cadherin gene are highly frequent in infiltrating lobular breast carcinomas [38] and diffuse gastric carcino- mas ...on E-cadherin expression ...
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Arf6 regulates EGF-induced internalization of E-cadherin in breast cancer cells
... EGF-induced E-cadherin internalization, the precise mechanisms under- lying this regulation were poorly ...of E-cadherin occurred in our experimental ...that E-cadherin only ...
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