Ebola virus (EBOV)
Comprehensive Functional Analysis of N Linked Glycans on Ebola Virus GP1
... Since complete deglycosylation of the core domains of GP1 did not negatively impact the expression of GP or the transduction of pseudotyped virions, we systematically combined N-linked glycan mutations in the MLD with ...
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REVIEW ON EBOLA VIRUS
... Ebola virus (EBOV) is considered one of the most aggressive infectious agents and is capable of causing death in humans and nonhuman primates (NHPs) within days of ...the Ebola envelope glycoprotein ...
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Ebola Virus: An Overview
... genus Ebola virus. The four are Bundibugyo virus (BDBV), Sudan virus (SUDV), Taï Forest virus (TAFV) and one simply called Ebola virus (EBOV, formerly Zaire Ebola ...
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Heparan sulfate is an important mediator of Ebola virus infection in polarized epithelial cells
... for Ebola virus disease (EVD), and therapy remains largely ...supportive. Ebola virus (EBOV) has broad tissue tropism and can infect a variety of cells including epithelial ...restrict ...
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Ebola Virus Disease: A Brief Review
... of Ebola virus is due to close reside with the wild animals like chimpanzees, baboons, African green monkeys, duikers and fruit bats (MyonycteristorquataandPteropodidae, Hypsignathusmonstrosus, ...
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EBOLA VIRUS - AN AYURVEDIC APPROACH .......
... genus Ebola virus. Four of the five known Ebola viruses, including EBOV, cause a severe and often fatal and hemorrhagic fever in humans and other ma mals, known as Ebola virus disease ...
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Ebola virus disease and critical illness
... blood Ebola virus RT-PCR result taken at least 3 days after the resolution of symptoms [33, ...However, Ebola virus can persist in certain body fluids after it is undetectable in the blood and ...
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Staufen1 Interacts with Multiple Components of the Ebola Virus Ribonucleoprotein and Enhances Viral RNA Synthesis
... ABSTRACT Ebola virus (EBOV) genome and mRNAs contain long, structured regions that could hijack host RNA-binding proteins to facilitate infection. We performed RNA affinity chromatography coupled with mass ...
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Suramin is a potent inhibitor of Chikungunya and Ebola virus cell entry
... Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes high fever, rash, and recurrent arthritis in ...America. Ebola virus (EBOV) is a member of the filovirus ...the Ebola ...
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A Study of the Ebola Virus Glycoprotein: Disruption of Host Surface Protein Function and Evasion of Immune Responses
... main Ebola virus glycoprotein (GP) is the only viral protein found on the surface of the Ebola virion and is therefore responsible for mediating attachment and entry of the virus into host ...
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Mutational Analysis of the Putative Fusion Domain of Ebola Virus Glycoprotein
... of virus infection, identification of the fusion domain is essential for understand- ing the overall process of virus ...influenza virus hem- agglutinin (HA), the hydrophobic amino terminus of HA 2 ...
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Reverse Genetics Demonstrates that Proteolytic Processing of the Ebola Virus Glycoprotein Is Not Essential for Replication in Cell Culture
... Ebola virus, a member of the family Filoviridae, is a nonseg- mented negative-strand RNA virus and is one of the most lethal human pathogens recognized to date (2, ...16). Ebola virus ...
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Host Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies
... 34. Carroll MW, Matthews DA, Hiscox JA, Elmore MJ, Pollakis G, Ram- baut A, Hewson R, García-Dorival I, Bore JA, Koundouno R, Abdellati S, Afrough B, Aiyepada J, Akhilomen P, Asogun D, Atkinson B, Ba- dusche M, Bah A, ...
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Assessment of the Potential for Spread of Deadly Ebola Virus across International Borders by Returnee Travelers and Humanitarian Health Workers from West Africa
... Abstract The recent Ebola Virus Disease (EVD) outbreak in West Africa is so far the largest and deadliest in recorded history. The rapid spread of the disease in the region and its potential for ...
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Curability of Ebola Virus – A Scientometric Approach to Ebola Virus Research
... Ebola virus cause hemorrhagic fevers — illnesses marked by severe bleeding (hemorrhage), organ failure and, in many cases, ...decades. Ebola virus live in animal hosts, and humans can contract ...
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Analysis of Linear B-Cell Epitopes of the Nucleoprotein of Ebola Virus That Distinguish Ebola Virus Subtypes
... of Ebola virus have been reported, and functional aspects of these MAbs were analyzed (7, 11, 23, ...of Ebola virus subtype Zaire for laboratory diagnostic ...of Ebola virus NP, ...
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Mathematical models for devising the optimal Ebola virus disease eradication
... for Ebola virus disease out- break modeling ...of Ebola medi- cation announced by the World Medical Association (WMA) brings hope to the Ebola infected ...of Ebola outbreak ...of ...
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Ebola Virus Binding to Tim 1 on T Lymphocytes Induces a Cytokine Storm
... IMPORTANCE Ebola virus infection is characterized by a massive release of inflam- matory mediators, which has come to be known as a cytokine ...lethal Ebola virus ...that Ebola ...
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Transmission dynamics and control of Ebola virus disease (EVD): a review
... with Ebola virus is known to occur in a certain fraction of exposed individuals ...the Ebola outbreak in the Democratic Republic of Congo in 1995, Eichner et ...
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AN OVER VIEW ON EBOLA VIRUS DISEASE
... Reston Ebola virus antibodies after the contact with sick pigs in the Philippines, but had no significant ...the Ebola rest on virus is not as great as threat as the other Ebola viruses ...
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