Ebola Virus Infection
Enhancement Of Ebola Virus Infection By Seminal Amyloid Fibrils
... worst Ebola virus outbreak on record, with the infected numbering over 28,000 and the dead more than ...disease, Ebola virus was found to persist in numerous anatomical locations and be shed ...
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Possible FDA-approved drugs to treat Ebola virus infection
... the Ebola virus (EBOV) thus ...treat Ebola virus infection with a cumulative use of both Miglustat and Toremifene to inhibit the virus effectively and ...EBOV infection ...
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Pre-Symptomatic Diagnosis of Ebola Virus Infection
... endemic infection such as ...from Ebola-infected blood compared to uninfected blood or compared to infections from other ...classify Ebola infection (group 1) from uninfected (group 2) or ...
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Human Ebola virus infection in West Africa: a review of available therapeutic agents that target different steps of the life cycle of Ebola virus
... Both clomiphene and toremifene have anti-EBOV activ- ity in both the Vero E6 (interferon-deficient African green monkey kidney epithelial cells) and HepG2 (human hepa- tocellular carcinoma) cell lines. The anti-EBOV ...
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Heparan sulfate is an important mediator of Ebola virus infection in polarized epithelial cells
... inhibited Ebola envelope-mediated gene transfer while vesicular stomatitis virus G protein pseudotyped vectors were only marginally affected ...EBOV infection of polarized Caco-2 ...basolateral ...
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Click here to download PDF version of the article !
... Ebola virus disease (EVD) described as “one of the world’s most virulent diseases” by WHO was popularly known as Ebola haemorrhagic fever in the ...The virus is transmitted to people from wild ...
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Ebola virus disease and critical illness
... influenza virus inhibitor, has been administered for compassionate use outside West Africa [37, 38, ...against Ebola [106], was administered to a small number of EVD patients for uncontrolled compassionate ...
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Viral Replication and Host Gene Expression in Alveolar Macrophages Infected with Ebola Virus (Zaire Strain)
... of Ebola virus, an in vitro culture system involving nonhuman primate alveolar macrophages was ...developed. Ebola virus replication in the alveolar macrophages was characterized by plaque ...
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Reverse Genetics Demonstrates that Proteolytic Processing of the Ebola Virus Glycoprotein Is Not Essential for Replication in Cell Culture
... Ebola virus, a member of the family Filoviridae, is a nonseg- mented negative-strand RNA virus and is one of the most lethal human pathogens recognized to date (2, ...16). Ebola virus ...
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Vol 27, No 5 (2014)
... Artificial nucleosides that competitively antagonize the natural ones on the viral polymerase are mainstream antiviral therapy, from the old days a generation ago, of treating herpes encephalitis with Ara-A, to the tens ...
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Ebola, the killer virus
... initial Ebola virus infection sites ...that Ebola virus mostly affects low-income countries, which might not have enough resources to develop a ...
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Curability of Ebola Virus – A Scientometric Approach to Ebola Virus Research
... In any subject, the scholars who are publishing their scientific communication continuously are called as continuant authors and those who publish sporadically are termed as transient authors. The more the continuant ...
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1-s2.0-S0196655319301531-main.pdf
... tant infection control ...current infection prevention threats including Ebola virus, Middle Eastern respiratory syndrome (MERS) coronavirus (CoV), carbapenem-resistant Enterobacteria- ceae ...
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Assessment of the Potential for Spread of Deadly Ebola Virus across International Borders by Returnee Travelers and Humanitarian Health Workers from West Africa
... Abstract The recent Ebola Virus Disease (EVD) outbreak in West Africa is so far the largest and deadliest in recorded history. The rapid spread of the disease in the region and its potential for ...
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REVIEW ON HISTORY AND EVIDENCE OF FRUIT BATS AS THE NATURAL RESERVOIR FOR EBOLA VIRUSES
... lethality. Ebola virus introduction into human population resulted from through single or multiple introductions from a zoonotic source into the human population then followed by ...of Ebola viruses ...
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Lesson learned from the investigation and response of Lassa fever outbreak, Margibi County, Liberia, 2018: case report
... of infection needs to be identified through conducting an environmental assessment to prevent future possible outbreaks through engaging communities’ in discouraging a rodent to enter the house, though keeping the ...
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Elucidating variations in the nucleotide sequence of Ebola virus associated with increasing pathogenicity
... Female Dunkin-Hartley guinea pigs were used for animal infection studies, with weights of 250 g to 350 g (Harlan Laboratories, UK). Before procedures involving the ma- nipulation of animals, guinea pigs were ...
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Ebola Virus Selectively Inhibits Responses to Interferons, but Not to Interleukin-1β, in Endothelial Cells
... of infection (MOI) of ...EZ infection suppressed basal MHC I protein expression, we asked whether infection with EZ also blocked induction of MHC I by ...viral infection of the cells is estab- ...
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The_Impact_of_Culture_on_the_Spread_of_the_Ebola_Virus_Disease.pdf
... There are essential differences between culture and science that need to be acknowledged. During the EVD outbreak, three major steps were adopted which highlighted the culture and science divide. First, the establishment ...
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Infection of Naïve Target Cells with Virus-Like Particles: Implications for the Function of Ebola Virus VP24
... Infectious virus-like particle (iVLP) systems have recently been established for several negative-strand RNA viruses, including the highly pathogenic Zaire ebolavirus (ZEBOV), and allow study of the viral life ...
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