Elk-1
Diallyl disulphide inhibits apolipoprotein(a) expression in HepG2 cells through the MEK1-ERK1/2-ELK-1 pathway
... to ELK-1 and inhibits apo(a) transcription. ELK-1 is a well-characterised common nuclear substrate, belongs to the family of Ets domain-containing transcription factors and it is activated by ...
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The Elk-1 and Serum Response Factor Binding Sites in the Major Immediate-Early Promoter of Human Cytomegalovirus Are Required for Efficient Viral Replication in Quiescent Cells and Compensate for Inactivation of the NF-κB Sites in Proliferating Cells
... for 1 h prior to ...6.8), 1% sodium dodecyl sulfate (SDS), 1 ⫻ protease inhibitor cocktail (P8340; Sigma), 1 ⫻ phosphatase inhibitor cocktail 1 (P2850; Sigma), 1⫻ phosphatase ...
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Activation of the Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat by the Ternary Complex Factor Elk-1
... and Elk-1 within the HTLV-1 LTR establishes a new mechanism of HTLV-1 transcriptional ...and Elk-1 are activated in response to mitogenic signals (8, 9, ...of Elk-1 ...
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Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A
... putative Elk-1-binding site existed in the -62~ -150 bp ...of Elk-1 and CIP2A promoter. The interaction of Elk-1 with the CIP2A promoter was abolished in a dose- dependent manner ...
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MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells
... finger 1 (MZF-1) and Ets-like protein-1 (Elk-1) correlates with PKCα expression in ...of Elk-1 facilitate the heterodimeric interaction between the two genes before the ...
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Original Article Downregulated protein expression of transcriptional activator ELK-1 in atrial myocardium of chronic AF patients
... activator ELK-1, one of the members of ETS family, has been shown to play an important role in regulating cell differentiation, It is reasonable to presume that ELK-1 participate in the ...
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ERK phosphorylation of MED14 in promoter complexes during mitogen induced gene activation by Elk 1
... that Elk-1 interacts directly with ...between Elk-1 and MED23 is no less enigmatic. The Elk-1 activation domain was shown to bind HeLa Mediator in a phosphorylation-dependent ...
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Opposing effects of Elk 1 multisite phosphorylation shape its response to ERK activation
... of Elk-1 TAD phosphorylation by ...N-labeled Elk-1 TAD (aa309- 429) and recombinant, unlabeled ERK2 at indicated reaction ...individual Elk-1 TAD sites. Grey cross-peaks denote ...
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Role of Regulatory Elements and the MAPK/ERK or p38 MAPK Pathways for Activation of Human Cytomegalovirus Gene Expression
... of the viral genome. The Elk-1 site alone, but not the proximal potential IE86 binding site, is a regulatory element of the UL4 promoter in virus-infected cells. A transcription factor binding site database ...
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Iron deficiency upregulates Egr1 expression
... Cells were washed once with phosphate-buffered saline (PBS) and collected with 500 ll RIPA buffer (50 mM Tris (pH 7.5), 5 mM EDTA, 1 % sodium deoxycholate, 1 % NP-40, and 0.1 % SDS, 400 mM NaCl) with ...
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DNA Methylation of miR-7 is a Mechanism Involved in Platinum Response through MAFG Overexpression in Cancer Cells
... MAFG, ELK-1, ABCA1 and MAPKAP1 ...and ELK-1 recovered their levels of expression after epigenetic treatment and overexpression of miR-7, thus indicating a possible regulation of these genes by ...
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AN ASSESSMENT OF MOOSE AND ELK TRAIN COLLISIONS IN ONTARIO, CANADA
... and elk (Cervus elaphus) in Ontario, we measured collisions along a 20 km segment of railway using post-winter railbed surveys (11 consecutive years), remote cameras, and radio-telemetered ...22 elk on the ...
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Network Security Log Analysis System Based on ELK
... The environment of the system mainly consists of two servers and one laptop. The four virtual machines (VM) are set up on one of the servers. VM 1-Shipper is equipped with the Scrapy reptile and Logstash ...
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Dehydration of Prions on Environmentally Relevant Surfaces Protects Them from Inactivation by Freezing and Thawing
... in 1 ⫻ SDS-PAGE sample buffer (final ...in 1 ⫻ Tris-Tween-buffered saline for 30 ...CA). Elk CWD samples were immunoblotted with MAb 8H4 (1:2,500; Abcam, Cambridge, ...
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Herbivory of sympatric elk and cattle on Lincoln National Forest, south-central New Mexico
... in elk populations throughout the game man- agement unit; Wright 2000; Hurd 2002; Hurd et ...of elk and cattle (Halbritter 2007; Halbritter and Bender 2011b), further indicate that generalized reductions of ...
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Winter Range Utilization by Elk and Mule Deer in Southeastern Washinton.
... sion, low density of the vegetation, scar- city of litter, and persistence of cheatgrass on the drier exposures and overused benches, and other factors indicated t[r] ...
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Declines of Bighorn Sheep, Ovis canadensis , on Deteriorating Winter Range in Jasper National Park, Alberta, 1981-2010
... Study area #2 (the Canyon) was frequented by one or more mature rams during the fall mating season, but rarely after December. On occasion, rams were observed traveling from the Canyon to Ram Pasture; this involved ...
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Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation
... shows total Erk on the same blots. (D) Luciferase activity from NF- κB luciferase or Elk luciferase in HeLa cells overexpressing WT MyD88, MyD88-E52A, or control plasmid. Values were normalized based on Renilla ...
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Home Ranges and Movements of Elk ( Cervus canadensis ) Restored to Southern Ontario, Canada
... Hartsmere Elk groups, as well as differences in movements of cow and bull Elk during the parturi- tion ...GPS-collared Elk was mon- itored and analyzed to determine when bull Elk moved to cow ...
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Some Effects of Chemical Sagebrush Control on Elk Distribution.
... The same procedures in the spring of 1959 revealed some 55 percent more pellet groups inside the Dry Dallas treatment than occurred on the surrounding untreated sage[r] ...
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