Endocrine pancreas
Effects of secretin, pancreozymin, or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man
... Enteric infusion of hydrochloric acid, or stimulation of gastric acid secretion by betazole, presumed to cause release of endogenous secretin, led to enhancement of insulin secretion during intravenous infusion of ...
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Zebrafish mnx1 controls cell fate choice in the developing endocrine pancreas
... of endocrine cell types is reminiscent of our results in the zebrafish, although in the murine case beta cells might be replaced by delta cells rather than alpha ...of endocrine pancreas development ...
12
Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets
... two pancreas developmental markers (SOX9 and PDX1) were observed between genotypes, leaving the etiology of this find- ing still ...exocrine pancreas in CF indi- viduals (65, ...ferret pancreas at ...
15
The simultaneous loss of Arx and Pax4 genes promotes a somatostatin producing cell fate specification at the expense of the α and β cell lineages in the mouse endocrine pancreas
... It was previously suggested that the levels of both Arx and Pax4 are regulated through a mutually inhibitory cross- regulatory circuit that controls the transcriptional state of both genes during endocrine ...
12
Tyrosine hydroxylase activity in the endocrine pancreas: changes induced by short-term dietary manipulation
... Our study is the first to demonstrate a measurable and modulated TH activity in the endocrine pancreas of nor- mal adult rats. Since similar TH activity values were re- corded in islets isolated from S and ...
6
A morphological basis for intercellular communication between alpha and beta cells in the endocrine pancreas
... While the role of the small tight junctions in rowing of the intercellular space is compatible with islets is fully open at present, the presence of gap juncgap junctions in these juncti[r] ...
6
Somatostatin blockade of acute and chronic stimuli of the endocrine pancreas and the consequences of this blockade on glucose homeostasis
... pancreatic endocrine secretion were studied by administration of a number of stimuli of either glucagon or insulin to over night fasted baboons with and without an infusion of linear ...
10
GABAergic system in the endocrine pancreas: a new target for diabetes treatment
... In the past five decades, the function of GABA in the CNS has been well documented. However, the presence of a GABAer- gic system within the pancreas as a potential target for treating diabetes mellitus emerged ...
9
Role of the endocrine pancreas in the kalemic response to acute metabolic acidosis in conscious dogs
... plasma potassium levels may rise, the increase is smaller than in mineral acid acidosis. The mechanisms responsible for the different effects of organic acid acidosis and mineral acid acidosis remain undefined, although ...
12
Effects of morphine on glucose homeostasis in the conscious dog
... This study was designed to assess the effects of morphine sulfate on glucose kinetics and on glucoregulatory hormones in conscious overnight fasted dogs. One group of experiments established a dose-response range. We ...
9
ISLET CELL ANTIBODIES IN DIABETES MELLITUS
... the endocrine pancreas was first reported in 1974 when Islet Cell Antibodies (ICAs) were detected in patients with diabetes mellitus together with autoimmune polyendocrine deficiencies 1 , and in diabetics ...
5
Effect of age and environmental factors on insulin release from the perfused pancreas of the rat
... isolated pancreas of each animal to determine maximal (300 mg/ml) glucose-stimulated insulin ...each pancreas was perfused with formalin fixative and processed for morphometric estimation of the mass of the ...
7
Multiple endocrine neoplasia type 1
... Multiple Endocrine Neoplasia type 1 (MEN1) is a rare autosomal dominant hereditary cancer syndrome presented mostly by tumours of the parathyroids, endocrine pancreas and anterior pituitary, and ...
9
β cell replication is the primary mechanism for maintaining postnatal β cell mass
... the endocrine pancreas from high rates of β cell replication and expansion of β cell mass in the 2 weeks after birth to steady-state levels of β cell ...in endocrine islet cells may offer an ...
7
BM MSCs Differentiated Insulin Producing Cells Produce More Insulin in Presence of EGF than of FGF
... 2005 Human Bone Marrow Mesenchymal Stem Cell Can Express Insulin and Key Transcription Factors of the Endocrine Pancreas Developmental Pathway upon Genetic and/or Micro Environmental Man[r] ...
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Cellular and molecular mechanisms coordinating pancreas development
... rodent pancreas development – from early organ induction to formation of the exocrine and endocrine pancreas – has vastly ...driving pancreas morphogenesis and ...early pancreas ...
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SIRT1 Deacetylates FOXA2 and Is Critical for Pdx1 Transcription and β-Cell Formation
... The entire pancreas was collected, flattened, and fixed in 10% formalin. The fixed pancreas was em- bedded with paraffin. Five µ m sections were cut with MICROM (HM 340E). The sections were stained with ...
13
Diabetes and other endocrine-metabolic abnormalities in the long-term follow-up of pancreas transplantation
... other endocrine metabolic abnormalities following transplantation are common and can increase morbidity and ...simultaneous pancreas kidney or not, seems to differentially influence the evolution of ...
9
A review on insulin presence and function in brain
... an endocrine hormone with receptor distribution in different parts of brain and has role in various neural functions such as; growth factor, modulating learning or memory, mood, neural growth and survival, also ...
6
Metastatic mixed acinar-endocrine carcinoma of the pancreas treated with a multidisciplinary approach: a case report
... compression in the gastric wall. Her anaemia was improved by transfusion and oral iron preparation. On physical examination, she had a soft, non-tender abdo- men without any palpable masses. The laboratory data showed ...
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