Endothelial glycocalyx
Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function
... the endothelial glycocalyx in regulating microvessel permeability was formalised in the fibre-matrix junction-break theory proposed by Curry and Michel in 1980 (Curry & Michel, ...the endothelial ...
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Three dimensional ultrastructure of capillary endothelial glycocalyx under normal and experimental endotoxemic conditions
... the endothelial glycocalyx layer in continuous and fenestrated capillaries was substantially thicker than in ...the endothelial glycocalyx presented as moss- or broccoli-like and covered the ...
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Hypervolemia increases release of atrial natriuretic peptide and shedding of the endothelial glycocalyx
... lial glycocalyx has been investigated in an experimental setting by our group ...the endothelial glycocalyx and histologically detectable destruction of the coronary vascular glycocalyx ...
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Exogenous nitric oxide requires an endothelial glycocalyx to prevent postischemic coronary vascular leak in guinea pig hearts
... coronary glycocalyx integrity is accompanied by leakage of fluid from the vascular compartment, resulting in swelling of the pericapillary intersti- tial space ...the endothelial glycocalyx is ...
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Sialic acids regulate microvessel permeability, revealed by novel in vivo studies of endothelial glycocalyx structure and function
... and endothelial glycocalyx in single microvessels A, two 26G needles (n) and two fine tubes (grey line) were inserted into each of the main barrels of the bevelled theta-style micropipette (tp) and glued in ...
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Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation
... induce glycocalyx degradation are ...the endothelial glycocalyx [19–21], suggesting that fluid resuscitation may cause iatrogenic glycocalyx degradation in septic patients via the induction of ...
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Endothelial glycocalyx conditions influence nanoparticle uptake for passive targeting
... delivery. Glycocalyx structure was modulated by serum deprivation or enzymatic cleavage of HS and subsequently supplementing exogenous HS, and probed using PEG-AuNP ...the glycocalyx structure greatly ...
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Original Article Changes of endothelial glycocalyx and effect of fluid resuscitation combined with norepinephrine on endothelial glycocalyx in early septic shock
... vascular endothelial glycocalyx in rabbits with early septic ...vascular glycocalyx shedding that led to increased expression in the ...of glycocalyx shedding in the development of sep- ...on ...
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The endothelial glycocalyx and its disruption, protection and regeneration: a narrative review
... The aim of this paper was to review and summarise the clinical findings relating to the biological functions of the glycocalyx layer and its damage and regeneration or protection. As a number of publications were ...
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Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients
... Commercial enzyme-linked immunosorbant assays (ELI- SAs) for soluble syndecan-1, chondroitin sulfate, heparan sulfate and hyaluronic acid were performed to quantify levels of endothelial glycocalyx ...
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Association of sublingual microcirculation parameters and endothelial glycocalyx dimensions in resuscitated sepsis
... regression line can be generated manually through the starting points of both slopes using PUNIAS (protein unfolding and nano- indentation analysis software, version 1.0, release 2.1, http://punias. free.fr). Projected ...
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Endothelial Glycocalyx Shedding in Pediatric Diabetic Ketoacidosis
... the glycocalyx, a mediator in NO production and release of anti-coagulation ...a glycocalyx, and the endothelial glycocalyx is known to extend 400-500 nm above the cell surface 154 ...The ...
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Structure and function of the endothelial glycocalyx in the microcirculation
... the endothelial glycocalyx, we used the lectin wheat germ agglutinin ...the endothelial layer. Previously, WGA staining on endothelial cells was decreased in a model of spontaneous kidney ...
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The role of endothelial glycocalyx in sepsis
... FSS, endothelial glycocalyx and cytoskeleton rearrangement due to FSS found that endothelial glycocalyx is an FSS transduction tool, and there is an FSS threshold that triggers the ...
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Endothelial glycocalyx degradation is more severe in patients with non-pulmonary sepsis compared to pulmonary sepsis and associates with risk of ARDS and other organ dysfunction
... the endothelial glycocalyx has been increasingly recognized as an important contributor to the pathophysiology of sepsis ...of glycocalyx degradation in patients with ...of glycocalyx degrada- ...
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Resuscitation Fluid Choices to Preserve the Endothelial Glycocalyx
... measuring endothelial glycocalyx status clinically are not yet routinely available outside of a re- search context and have unvalidated clinical ...the endothelial glycocalyx is likely to be ...
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Loss of the endothelial glycocalyx is associated with increased E-selectin mediated adhesion of lung tumour cells to the brain microvascular endothelium
... for endothelial adhesion molecules in the tethering of CTCs to the ...the endothelial glycocalyx which, in health, shields the adhesion molecules from circu- lating ...cells. Glycocalyx loss ...
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Mechanism of vascular endothelial dysfunction causing atherosclerosis: vascular endothelial glycocalyx
... vascular endothelial dysfunction is commonly observed with damage of vascular endothelial glycocalyx, an extracellular matrix-bound to and encapsulating the endothelial cell lining the blood ...
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Water content of the endothelial glycocalyx layer estimated by volume kinetic analysis
... the glycocalyx water volume in ...the glycocalyx water is primar- ily that this volume is released to the circulating plasma when the glycocalyx layer be- comes ...However, glycocalyx ...
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Effects of two weeks of metformin treatment on whole-body glycocalyx barrier properties in db/db mice
... The endothelial glycocalyx is the polysaccharide rich, gel-like layer located at the luminal side of all blood ves- sels, which has been demonstrated the last decades to be a gatekeeper of the vascular wall ...
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