enhanced solubility
<p>Electrosprayed Polymeric Nanospheres for Enhanced Solubility, Dissolution Rate, Oral Bioavailability and Antihyperlipidemic Activity of Bezafibrate</p>
... technique. Solubility, release rate, bioavailability in male Sprague Dawley rats, and lipid pro fi le attributes in Wistar rats were assessed in comparison with beza fi brate plain ...14-fold enhanced ...
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ENHANCED SOLUBILITY OF NON STEROIDAL ANTI INFLAMMATORY DRUGS BY HYDROXYL TERMINATED S TRIAZINE BASED DENDRIMERS
... for enhanced solubility of NSAIDs by dendrimer could be either hydrophilic interaction or hydrogen bonding or both ...from solubility resultsFig. 3-5(A-C) that solubility of NSAIDS increased ...
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Liquisolid Compact Tablet of Candesartan Cilexetil with Enhanced Solubility using Neusilin US2, Aerosil 200 and Transcutol HP
... showed enhanced solubility, dis- solution rate and intestinal permeability by ...less enhanced permeability was obtained than earlier work ...
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Enhanced Solubility of Modafinil via Solubilization Techniques
... modafinil solubility. Methods: Altered solubility study of modafinil was carried out in numerous water-cosolvent ...phase solubility analysis. Furthermore, solubility behavior with two ...
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Formulation and in vitro characterization of Carbamazepine polymeric nanoparticles with enhanced solubility and sustained release for the treatment of Epilepsy
... The idea behind selecting carbamazepine as active pharmaceutical ingredient is that it is an effective anti-epileptic drug, which is characterized by irregular and often slow absorption into the systemic circulation [7]. ...
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Formulation and Evaluation of Self-microemulsifying drug delivery system of Curcumin for enhanced solubility and dissolution.
... The solubility of curcumin in various oils, surfactants, co-surfactants and Oil; surfactant mixture was measured using shake flask method 8 - 12 . An excess amount of curcumin was added into each vehicle followed ...
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Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles
... Abstract: Among numerous drug-delivery approaches, reconstituted high-density lipoprotein (rHDL) nanocarriers have proven particularly applicable for delivering highly hydrophobic drugs. In this study, we have ...
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Linagliptin loaded Solid-SMEEDS for enhanced solubility and dissolution: Formulation development and optimization by D-optimal design
... improve solubility and dissolution profile of ...significantly enhanced drug release profile of the Linagliptin from the ...the solubility and dissolution profile of poorly soluble anti- diabetic ...
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Comparative study on solid self-nanoemulsifying drug delivery and solid dispersion system for enhanced solubility and bioavailability of ezetimibe
... The presence of self-nanoemulsifying oil formulation fields that could self-emulsify after dilution and slight agitation is recognized using a ternary phase diagram. On the basis of the solubility study, Capryol ...
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Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance
... Its solubility capacity was about 96-fold higher than that in ...of solubility in oils was high due to the lipid-like structure and properties of ...and enhanced the solubility were selected ...
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Preparation and Characterization of Tadpole and Sphere Shaped Hemin Nanoparticles for Enhanced Solubility
... the solubility of ...hemin solubility. Although there was some progress on the solubility improvement of heme iron, industrialization was not easy due to the complicated prep- aration ...the ...
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Preparation and characterization of nimodipine-loaded nanostructured lipid systems for enhanced solubility and bioavailability
... the solubility study of the NMP in the liquid lipid was carried out. As shown in Table 2, the best solubility was achieved in Labrafac PG at 24.88 ± 2.1 mg/g, which was notably higher than OA of 4.65 ± 0.8 ...
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EVAPORATIVE NANOCRYSTALLIZATION FOR ENHANCED SOLUBILITY AND BIOAVAILABILITY OF SULFASALAZINE
... The purpose of the present study was to increase the aqueous solubility of sulfasalazine (0.045mg/ml) by nanaocrystallization and preparation of controlled multiparticulate drug delivery. Sulfasalazine is mainly ...
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FORMULATION AND CHARACTERIZATION OF SOLID MICROEMULSION OF DARUNAVIR FOR ENHANCED SOLUBILITY AND DISSOLUTION
... INTRODUCTION: Successful oral delivery of drugs has always remained a challenge to the drug delivery field, since approximately 40% of the new drug candidates have poor water solubility, and thus oral delivery is ...
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Formulation, In vitro and In vivo Analysis of Cyclodextrin Complexed Albendazole Composites for Enhanced Solubility
... low solubility in ...the solubility and dissolution rate by complexing with cyclodextrins by kneading method and to compare the solubility between hydroxypropyl beta cyclodextrin and beta ...
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Solubility prediction of satranidazole in aqueous N,N-dimethylformamide mixtures using extended hildebrand solubility approach
... The solubility of satranidazole in several water–N,N‑dimethylformamide mixtures was analysed in terms of solute– solvent interactions and data were treated on the basis of extended Hildebrand solubility ...
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Solubility Prediction of Satranidazole in Propylene Glycol-Water Mixtures Using Extended Hildebrand Solubility Approach
... the solubility of satranidazole in PG-water mixtures within the accuracy ordinarily achieved in such experimental solubility ...the solubility of satranidazole in any other binary solvent ...which ...
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Effect of Cyclodextrin Complexation on the Aqueous Solubility of Diazepam and Nitrazepam: Phase Solubility Analysis, Thermodynamic Properties
... nitrazepam solubility in the presence of various con- centrations of CDs at several temperatures revealed that the solubility of diazepam and nitrazepam increased pro- portionally with an increase in ...
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Predicting melting points of organic molecules : applications to aqueous solubility prediction using the General Solubility Equation
... We used SMILES strings to calculate 2D descriptors from the open source Java library the Chemistry Development Kit (CDK). [19] A list of all available descriptors in the CDK and definitions can be found at the website ...
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Enhanced dissolution and solubility of Epalrestat with β-Cyclodextrin ternary complex using Arginine
... in solubility and dissolution using Epalrestat with β-cyclodextrin ternary complex with addition of ...Phase solubility, saturation solubility, dissolution and stability studies were carried ...phase ...
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