Eotaxin-1
Astragalin inhibits airway eotaxin-1 induction and epithelial apoptosis through modulating oxidative stress-responsive MAPK signaling
... (St. Louis, MO), as were all other reagents, unless specific- ally stated elsewhere. Fetal bovine serum (FBS), penicillin- streptomycin and trypsin-EDTA were purchased from the Lonza (Walkersville, MD). The human ...
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Analysis of single nucleotide polymorphism in the promoter and protein expression of the chemokine Eotaxin 1 in colorectal cancer patients
... the eotaxin-1 gene, -384A>G, has been showed to have a functional role in regulation of gene expression, and thus influences the eotaxin-1 ...of eotaxin-1 in asthmatic ...
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Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes
... chemokine eotaxin-1; CCR: CC chemokine receptors; DAG: diacylglycerol; DMEM: Dulbecco ’ s modified Eagle ’ s medium; ECL: enhanced chemiluminescence; ERK: extracellular signal-regulated kinase; FBS: fetal ...
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Eotaxin-1 in exhaled breath condensate of stable and unstable asthma patients.
... in eotaxin-1 levels between patients with stable and unstable asthma and healthy ...of eotaxin-1 in EBC significantly correlate with exhaled nitric oxide levels - a more and more appreciable ...
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Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene
... on Eotaxin-1 expression in ...in Eotaxin-1 secretion following IL-1β challenge (Figure ...indeed Eotaxin-1 is specifically inhibited by NRF2 activation in ...in ...
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CCL11 or Eotaxin-1: An Immune Marker for Ageing and Accelerated Ageing in Neuro-psychiatric Disorders
... Resveratrol and its metabolites modulate the expression of CCL11. In 2011, Yang et al. investigated the effects of resveratrol in modulating inflammation by determining the expression and release of CCL11 in cultured ...
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Eosinophil and T cell markers predict functional decline in COPD patients
... Research has indicated that eosinophils[1] and T lym- phocytes[2,3] are important determinants of disease sta- bility in COPD patients. Given these studies, we sought to determine if eosinophil or T cell related ...
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TNF up-regulates Pentraxin3 expression in human airway smooth muscle cells via JNK and ERK1/2 MAPK pathways
... of eotaxin-1/ CCL11 expression in the airway inflammatory [32] and structural cells including HASMC [33] combined with the fact that PTX3 enhanced the eotaxin-1/CCL11 release in HASMC suggests ...
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Neuronal eotaxin and the effects of ccr3 antagonist on airway hyperreactivity and M2 receptor dysfunction
... pig eotaxin showed positive staining in air- way epithelium, smooth muscle, and nerves (Figure ...increased eotaxin staining in all 3 tissues (Figure 7, D–J). Eotaxin-1 was also expressed in ...
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HIV infection is associated with higher levels of monocyte chemoattractant protein 1 and eotaxin among people with recent hepatitis C virus infection
... IL-8, eotaxin-1 (or CCL11), IFN-g, interferon-gamma inducible protein-10 (IP-10, or CXCL10), monocyte chemotactic protein 1 (MCP-1, or CCL2), macrophages inflammatory proteins 1 alpha ...
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Eotaxin 3 and a uniquely conserved gene expression profile in eosinophilic esophagitis
... identified eotaxin-3 as the gene most highly induced in ...of eotaxin-3 expression in the esophagus strongly correlated with disease severity based on basal layer expansion and levels of eosinophils and ...
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Cytokines profiling by multiplex analysis in experimental arthritis: which pathophysiological relevance for articular versus systemic mediators?
... cartilage, 1 = loss of proteoglycan staining in the superficial layer, 2 = complete loss of proteoglycan staining, and 3 = complete loss of ...normal, 1 = mild loss of cortical bone at few sites, 2 = ...
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Early phase resolution of mucosal eosinophilic inflammation in allergic rhinitis
... to one biopsy occasion only and parallel group analyses. This was also done to avoid too much discomfort by the biopsy procedures and prevent dropouts. An additional consideration was that the institution of treatment ...
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Anti eotaxin 2 antibodies attenuate the initiation and progression of experimental atherosclerosis
... that eotaxin-2/CCL 24 may play an active role in the ...of eotaxin-2/CCL 24 on atherogenesis is the recent observation that it induces activation of the plaque destabilizing proMMP-2 and of EGF-receptor in ...
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Analysing the eosinophil cationic protein - a clue to the function of the eosinophil granulocyte
... as eotaxin are produced in elevated levels and attract ele- vated numbers of eosinophils to the lumen and bronchi of the lungs in asthma [49] (Figure 4B), the nasal mucosa in allergic rhinitis [48] (Figure 3B) and ...
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Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids
... (20). Eotaxin is thought to be important in recruiting eosinophils to the airway after allergic stimulation because the time course of its appearance is congruent with that of eosinophil recruitment (15, 18, 21, ...
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Human eosinophil adhesion and degranulation stimulated with eotaxin and RANTES in vitro: Lack of interaction with nitric oxide
... RANTES, eotaxin, eotaxin-2, MCP-3 and MCP-4 have been sug- gested to contribute to bronchial eosinophilia in patients with asthma ...mice, eotaxin increases the CD11b and VLA-4 expressions, with ...
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Comparable Function of γ-Tocopherols in Asthma Remission by Affecting Eotaxin and IL-4
... Eotaxin could regulate eosinophil traffick- ing into the airways along with other chemotac- tic factors, such as IL-4 which is a pleiotropic cy- tokine that elicits a wide spectrum of physiological and pathogenic ...
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Relationship between interleukin 5 and eotaxin in regulating blood and tissue eosinophilia in mice
... taneous eotaxin and IL-5 and suggest that basal levels of IL-5 may play a critical role in regulating eosinophil homing, per- haps by activating adhesion systems in the vascular endothe- lium (9, ...
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Mast cells are required for experimental oral allergen–induced diarrhea
... Microarray dissection of experimental intestinal anaphylax- is. To further understand the pathogenesis of experi- mental gastrointestinal allergic responses, we examined global mRNA expression patterns in the ...
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