Epitope prediction
Specificities of Human CD4+ T Cell Responses to an Inactivated Flavivirus Vaccine and Infection: Correlation with Structure and Epitope Prediction
... cell epitope prediction algorithms ...cell epitope prediction algorithms predict MHC- II–peptide binding affinities only (37, 38) (with an excellent match to experimentally determined ...
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Immunoinformatics and epitope prediction in the age of genomic medicine
... T-cell epitope prediction tools as discussed above to predict transcripts or poten- tial antigen sequences results in a set of potential epitopes for a given set of HLA ...for epitope-driven ...
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Cloning, expression and T cell epitope prediction of fbpA and fbpB genes of Mycobacterium tuberculosis clinical isolates
... The effective treatment and accurate diagnosis of tuberculosis (TB) are not established yet. The Bacillus Chalmette-Guerin vaccine did not provide significant results in the prevention of TB and had only 0-80% efficacy. ...
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Homology Modeling and Conformational Epitope Prediction of Envelope Protein of Alkhumra Haemorrhagic Fever Virus
... The best selected model was subjected to predict its possible conformational epitopes with DiscoTope 2.0 server (Haste Andersen et al. 2006), which uses a combination of amino acid statistics, spatial information, and ...
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Computational Methods in Linear B cell Epitope Prediction
... To study the correlation between location of linear epitopes and amino acid scale based profiles, Blythe and Flower have performed an extensive estimation of 484 amino acid propensity scales in a dataset of 50 proteins ...
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ANALYSIS OF HYDROPHOBICITY AND ANTIGENIC EPITOPE PREDICTION FROM D. MEDINENSIS
... antibody epitope from ATP synthetase subunit 6 sequences with the consideration of the parameters such as hydrophilicity, flexibility, accessibility, turns, exposed surface, polarity and antigenic propensity of ...
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Structural analysis and epitope prediction of HCV E1 protein isolated in Pakistan: an in silico approach
... antigen prediction server was used for analyzing the antigenicity of the E1 protein ...B-cell prediction using 3D structure of the HCV E1 protein of ...
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IN SILICO EPITOPE PREDICTION AND HOMOLOGY MODELING OF ENVELOPE SURFACE GLYCOPROTEIN GP160, PRECURSOR REGION FROM HUMAN IMMUNO DEFICIENCY VIRUS 1
... ABSTRACT: The development of a highly effective AIDS vaccine will depend on the success of designing immunogens that will elicit immune response against broadly neutralizing antibodies to naturally circulating strains of ...
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In silico Homology Modeling and Epitope Prediction of NadA as a Potential Vaccine Candidate in Neisseria meningitidis
... molecules to facilitate its colonization in human nasopharynx track. Neisseria meningitidis is a major cause of mortality from severe meningococcal disease and septicemia. Neisseria meningitidis adhesion, NadA, is a ...
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IN-SILICO T-CELL EPITOPE PREDICTION TOOL OF HEPATITIS C VIRUS (HCV)
... To get authentic and reliable model for prediction of the T-Cell epitopes of HCV, the protein sequence of hepatitis C virus (HCV) is retrieved from research papers (15-33) via pubMed-NCBI (www.ncbi.nlm.nih.gov ...
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Evaluation of recombinant multi epitope proteins for diagnosis of goat schistosomiasis by enzyme linked immunosorbent assay
... multi- epitope proteins were constructed and their potential as diagnostic antigens for goat schistosomiasis was evalu- ated in this ...of epitope prediction, several online software analytical ...
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Immunoinformatics approach for the study of CD4+ epitopes of HIV 1 Gag protein restricted to HLA DRB1*07 Allele
... based epitope prediction based on various algorithms would aid playing promising role in screening of and selection of CD4+ T cell Gag epitopes restricted to ...
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In Silico Characterization of Epitopes from Human Rotavirus VP7 Genotype G9 Design for Vaccine Development
... an epitope from Rotavirus genotype G9 as a promising epitope candidate for future vaccine ...analysis, Prediction of Protein Structure, Physicochemical Properties of Protein and Epitope ...
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Prediction of CTL epitope, in silico modeling and functional analysis of cytolethal distending toxin (CDT) protein of Campylobacter jejuni
... The 3D protein structure predicted by Modeller was used as an input, each residue in the query protein will be given a score according to its neighborhood residues information. Higher score corresponds to higher prob- ...
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American Journal of Medical and Biological Research
... epitopes prediction is done by immune epitope database ...linear epitope prediction analysis and T cell epitopes using Major Histocompatibility Complex class I and ll binding prediction ...
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An Integrated In-Silico Approach to Develop Epitope-Based Peptide Vaccine against SARS-CoV-2
... hydrophilicity, prediction of linear epitope and accessibility of surface ...linear epitope prediction analysis [21], Kolaskar and Tongaonkar antigenicity scale, Emini surface accessibility ...
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Analysis of antibody induction upon immunization with distinct NTS DBL1α domains of PfEMP1 from rosetting Plasmodium falciparum parasites
... B-cell epitope prediction is inform- ative; however, there might be a tendency for skewing to- wards surface epitopes that are present in unstructured ...
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ANALYSIS OF HYDROPHOBICITY AND ANTIGENICITY OF HEAT SHOCK PROTEIN 70 FROM GWD
... antibody epitope from Heat shock 70 protein sequences with the consideration of the parameters such as hydrophilicity, flexibility, accessibility, turns, exposed surface, polarity and antigenic propensity of ...
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Immunoinformatics Approach Identified Two Highly Conserved B and T Cell Epitopes, LEASKRWAF and DSPLEASKRWAFRTG, for Effective Vaccine Design against Ebola and Marburg Viruses
... Nowadays, epitope based vaccine design against lethal viruses through bioinformatics has become popular because of its short study time, increased strength to predict effective epitopes and the availability of ...
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Journal of Applied & Environmental Microbiology
... Linear Epitope Prediction, Emini surface accessibility and Kolaskar and Tongaonkar antigenicity method in the IEDB, based on the default threshold of the prediction ...Linear Epitope ...
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