Estrogen/analysis*
<p>Risk analysis of systemic levels of estrogen and adipokines as well as estrogen receptors from PBMCs in childbearing and perimenopausal women with obesity</p>
... of estrogen, ERs, and adipokines in women of childbearing and perimenopausal ...The estrogen levels of perimeno- pausal women were signi fi cantly lower relative to those in women of childbearing ...
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Effect of Menstrual Cycle Related Estrogen Fluctuations on Working Memory
... that estrogen receptors are transiently expressed in the PFC of female rhesus monkeys during early brain development (Handa, Connolly, and Resko, 1988; MacLusky, Naftolin, and Goldman-Rakic, 1986; Pomerantz et ...
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Farnesyl transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF 7 cell growth through estrogen receptor dependent and independent pathways
... of analysis is not really precise enough to definitively establish additivity between two agents, the methodology does identify clear additivity with two different FTIs with diverse molecular struc- ...
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BRCA1 And Estrogen/Estrogen Receptor In Breast Cancer: Where They Interact?
... suggesting E-ER signaling promoted glycolysis is a very early event that associates with tumorigenesis. It was shown that the genes maximally induced by es- trogen treatment after relatively long time (160 mins) ...
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Pseudoangiomatous Stromal Hyperplasia: A Case Report
... “Immunocytochemical analysis of estrogen and progesterone receptors in benign stromal lesions of the breast: evidence for hormonal etiology in pseudoangiomatous hyperplasia of mammary stroma,” American ...
5
Sex differences and the protective influence of estrogen in a mouse model of demyelinating disease
... temporal analysis of demyelination in the lateral corpus callosum indicates 7 weeks of cuprizone treatment is optimal for detecting marked demyelination in SJL ...
170
Estrogen signaling effects on muscle-specific immune responses through controlling the recruitment and function of macrophages and T cells
... Damaged TA muscles were collected and minced and then gently digested with 0.2% IIcollagenase at 37 °C for 45 min twice. Total cells isolated from muscle homogenate were re-suspended in fluorescence-activated cell ...
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Lead Optimization of Benzoxepin Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype Specific ER alpha and ER beta Activity
... of duplicate compounds and compounds containing mis-assigned atom types were discarded leaving 39 actives and 1125 inactives for docking using FRED 3.0.1. 62 63 ERβ antagonists (32 compounds) were obtained from the work ...
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Colorectal cancer in relation to postmenopausal estrogen and estrogen plus progestin in the Women’s Health Initiative clinical trial and observational study
... this analysis if they were post- hysterectomy and either taking the same daily ...this analysis, including 6756 women who were using the same daily CEE/MPA combination as studied in the CT, and 25,328 ...
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Tamoxifen may prevent both ER+ and ER breast cancers and select for ER carcinogenesis: an alternative hypothesis
... meta- analysis of patients with ER+ or progesterone receptor posi- tive (PR+) primary tumors showed 22% (range ...subset analysis of cases from the BCPT, suggest that tamoxifen is effective in preventing ...
6
The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I SPY 2 randomized neoadjuvant setting
... ANOVA: Analysis of variance; AUC: Area under the curve; DLDA: Diagonal linear discriminant analysis; EGFR: Epidermal growth factor; ER α : Estrogen receptor alpha; EU FP7: European Union 7th ...
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Chinese herb mix Tiáo Gēng Tāng possesses antiaging and antioxidative effects and upregulates expression of estrogen receptors alpha and beta in ovariectomized rats
... Funded by Shanghai Leading Academic Discipline Project supported by Science and Technology Commission of Shanghai (S30303) and National Natural Science Foundation of China (30772820). We thank professor Jian- wen Liu and ...
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Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines
... served estrogen-responsive genes by mapping the human genes to a list of known (experimentally vali- dated by ChIP-chip and ChIP-seq analysis) ER binding sites ([20,21] (Fun et al 2010; personal ...
15
The Risk of Relationship between Hormonal Replacement Therapy and Cancer
... oral estrogen therapy, pass through the liver induces increased synthesis of various proteins such as clotting factors, carrier and genotypic sex steroid binding globulin (SHBG), which may cause ...
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Differential expression of breast cancer associated genes between stage and age matched tumor specimens from African and Caucasian American Women diagnosed with breast cancer
... be estrogen and progesterone receptor- negative ...of estrogen or progesterone re- ceptor status precludes treatment with tamoxifen or tras- tuzumab ...
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Hypothyroidism, Maternal Obesity and Self Reported Snoring As Risk Factors for Pregnancy Induced Hypertension
... mass raising the diaphragm and tracheal shortening are the most likely explanations 4,5 Also pharyngeal edema and weight gain contribute to upper airway resistance. Nasal congestion and rhinitis are common during ...
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Estrogen receptor transcription and transactivation Basic aspects of estrogen action
... of estrogen produc- tion by the ovaries. Estrogen replacement therapy has a cardiovascular protective effect in postmenopausal women, significantly decreasing the risk of developing ath- erosclerosis and ...
7
ALZHEIMER’S DISEASE: A REVIEW
... In these circumstances estrogen after administration improves the cognitive function.In this case raloxifene which is a selective estrogen receptor modulator reduces the risk [r] ...
9
Download Download PDF
... 2 estrogen receptors that simultaneously affect the body’s estrogen ...the estrogen receptors derived from the ovaries (E2 receptors) so that researchers need to choose the conditions in which E1 ...
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Estrogen receptor transcription and transactivation Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer
... A considerable number of studies have documented the fact that growth factors (eg epidermal growth factor [EGF], insulin-like growth factor), cAMP and other agents (eg dopamine) can stimulate activity of the ER and also ...
10