Ethyl Methanesulfonate
Brahmarasayana protects against Ethyl methanesulfonate or Methyl methanesulfonate induced chromosomal aberrations in mouse bone marrow cells
... It is well known that the genome of all the organisms including human is susceptible to damages caused by vast array of both endogenous and exogenous DNA damaging agents. Repair of such DNA damages play an important role ...
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Elevated ethyl methanesulfonate (EMS) in nelfinavir mesylate (Viracept®, Roche): overview
... In mid-May 2007, Roche received reports from France and Spain of a strange odour associated with bottles of nelfi- navir, including one patient reporting nausea and vomit- ing. Investigations revealed that there were ...
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Ethyl Methanesulfonate (EMS) Mediated Mutagenesis of Cucumber (Cucumis sativus L )
... Ethyl methanesulfonate (EMS) is a stable and effective chemical mutagen. In this study, cucumber (Cucumis sativus L. cv. “Shannong No. 5”) seeds were treated by 1% EMS for 12 h, 24 h and 48 h to optimize ...
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Irrigation’s effect and applied selection on the fiber quality of Ethyl MethaneSulfonate (EMS) treated upland cotton (Gossypium hirsutum L.)
... Background: Producing rainfed cotton ( Gossypium hirsutum L.) with high fiber quality has been challenging in the Texas High Plains because of extended periods of insufficient rainfall during sensitive boll developmental ...
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EFFECTS OF DOSE ON THE INDUCTION OF DOMINANT-LETHAL MUTATIONS AND HERITABLE TRANSLOCATIONS WITH ETHYL METHANESULFONATE IN MALE MICE
... On the other hand, for the two high doses (250 and 300 mg/kg) where high dom- inant-lethal effects led to preimplantation embryonic death and consequent classification of [r] ...
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Morphological Changes of Capsicum annuum L. Induced by Ethyl Methanesulfonate (EMS) at M2 Generation
... The objective of this study was to identify morphological variation in M2 plants of Capsicum annuum derived from seeds treated with ethyl methane sulfonate (EMS). The M1 generation was developed by treated seeds ...
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EFFECTS OF X RAYS AND ETHYL METHANESULFONATE ON THE CHLOROPHYLL B LOCUS IN THE SOMA AND ON THE THIAMINE LOCI IN THE GERMLINE OF ARABIDOPSIS
... Though the investigations reported below had been designed to study somatic recombination and genetic control of thiamine synthesis, by-product information has been obtained on the[r] ...
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Whole-Genome Effects of Ethyl Methanesulfonate-Induced Mutation on Nine Quantitative Traits in Outbred Drosophila melanogaster
... We induced mutations in Drosophila melanogaster males by treating them with 21.2 mm ethyl methanesulfo- nate (EMS). Nine quantitative traits (developmental time, viability, fecundity, longevity, metabolic rate, ...
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DNA SEQUENCE ANALYSIS OF MUTAGENICITY AND SITE SPECIFICITY OF ETHYL METHANESULFONATE IN Uvr+ AND UvrB- STRAINS OF ESCHERICHIA COLI
... An analysis of mutation frequencies with respect t o neighboring base sequence, in the two strains, shows that 06-ethylguanine lesions adjacent to A:T base pairs present bette[r] ...
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GENETIC EFFECTS OF ETHYL METHANESULFONATE IN COMBINATION WITH COPPER AND ZINC IONS ON ARABIDOPSIS THALIANA
... Metallic ions like calcium and magnesium are essential for the integrity of the chromosomes (STEFFENSEN and BERGERON 1959) and alkylating agents used in combination with[r] ...
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Isolation of Ethyl Methanesulfonate-Induced Gametophytic Mutants in Arabidopsis thaliana by a Segregation Distortion Assay Using the Multimarker Chromosome 1
... ( J and L) Higher magnification of generative cells in mutant and wild type. Nuclear membranes and cell membranes appear to be intact in mutant pollen; however, no accumulation of lipid [r] ...
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ORGANIZATION OF THE RUDIMENTARY WING LOCUS IN DROSOPHILA MELANOGASTER. I. THE ISOLATION AND PARTIAL CHARACTERIZATION OF MUTANTS INDUCED WITH ETHYL METHANESULFONATE, ICR–170 AND X RAYS
... Based on the genetic studies of CARLSON (1971) and enzyme activity meas- urements using certain mutants described by CARLSON, a variety of investigators have concluded that [r] ...
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COMPARISON OF SOMATIC REVERSIONS BETWEEN THE IVORY ALLELE AND TRANSPOSON-CAUSED MUTANT ALLELES AT THE WHITE LOCUS OF DROSOPHILA MELANOGASTER AFTER LARVAL TREATMENT WITH X RAYS AND ETHYL METHANESULFONATE
... In contrast, the frequency of X-ray-induced reversion of either the UZ strain or the d strain did not increase with the age at the time of irradiation (Table 2). This resul[r] ...
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ETHYL METHANESULFONATE-INDUCED REVERSION OF BACTERIOPHAGE T4rII MUTANTS
... The probability of copy error (c) characteristic of a given mutational mecha- nism will determine whether the frequency of induced mutations is as high as or lower than[r] ...
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ANALYSIS OF CHROMOSOME 4 IN DROSOPHILA MELANOGASTER . II: ETHYL METHANESULFONATE INDUCED LETHALS
... SHANNON, KAUFMAN and JUDD (1970) have reported that 113 lethal and semilethal recessive point mutations, which map between the X chromosome loci of zeste and white, be[r] ...
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MUTATIONAL RESPONSE OF HABROBRACON OOCYTES IN METAPHASE AND PROPHASE TO ETHYL METHANESULFONATE AND NITROGEN MUSTARD
... Nitrogen mustard [methyl bis ( p-chloroethyl) amine hydrochloride] has been used on the different stages of oogenesis in Habrobracon, and a 20-fold difference in sensitivity betw[r] ...
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GENETIC EFFECTS OF ETHYL METHANESULFONATE AND GAMMA RAY TREATMENT OF THE PROEMBRYO IN MAIZE
... These data show that EMS, like gamma rays, is very effective in inducing losses of dominant markers; and the rates of losses of different endosperm and seedling markers, in most ca[r] ...
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VIABILITY MUTATIONS INDUCED BY ETHYL METHANESULFONATE IN DROSOPHILA MELANOGASTER
... the EMS-induced mutant polygenes was found to be similar to that of spontaneous mutant polygenes: coupling heterozygotes manifested overdominance, and the heterozygous effects s[r] ...
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Inactivation of Bacteriophage T4 by Ethyl Methanesulfonate: Influence of Host and Viral Genotypes
... These strains included mutants exhibiting increased sensitivity to UV irradiation v, x, y, and combinations thereof; mutants defective in DNA synthesis ts mutations in DNA polymerase gen[r] ...
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NATURE OF ETHYL METHANESULFONATE INDUCED REVERSIONS OF lac- MUTANTS OF ESCHERICHIA COLI
... These results support the hypothesis that the genetic alteration restor- ing P-galactosidase activity and lactose utilizing ability to (some) nonfeeder revertants is a sup[r] ...
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