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Evolutionary rate

New Insights into the Evolutionary Rate of Hepatitis B Virus at Different Biological Scales

New Insights into the Evolutionary Rate of Hepatitis B Virus at Different Biological Scales

... The evolutionary rates of hepatitis B virus (HBV) estimated using contemporary sequences are 10 2 to 10 4 times higher than those derived from archaeological and genetic ...the evolutionary rate of ...

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Cross border spread, lineage displacement and evolutionary rate estimation of rabies virus in Yunnan Province, China

Cross border spread, lineage displacement and evolutionary rate estimation of rabies virus in Yunnan Province, China

... Results: The RABV N gene evolutionary rate was estimated to be 1.88 × 10 − 4 (1.37 – 2.41 × 10 − 4 , 95% Bayesian credible interval, BCI) substitutions per site per year. Phylogenetic reconstructions show ...

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Evolutionary rate and duplicability in the Arabidopsis thaliana protein protein interaction network

Evolutionary rate and duplicability in the Arabidopsis thaliana protein protein interaction network

... and evolutionary rate is independent of potential confounding factors (gene duplicability, expression level and breadth, and the length of the encoded products), suggesting a direct effect of the network ...

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Evolutionary Rate Covariation in Meiotic Proteins Results from Fluctuating Evolutionary Pressure in Yeasts and Mammals

Evolutionary Rate Covariation in Meiotic Proteins Results from Fluctuating Evolutionary Pressure in Yeasts and Mammals

... ABSTRACT Evolutionary rates of functionally related proteins tend to change in parallel over evolutionary ...Such evolutionary rate covariation (ERC) is a sequence-based signature of ...

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Unequal Evolutionary Rates in the Human Immunodeficiency Virus Type 1 (HIV-1) Pandemic: the Evolutionary Rate of HIV-1 Slows Down When the Epidemic Rate Increases

Unequal Evolutionary Rates in the Human Immunodeficiency Virus Type 1 (HIV-1) Pandemic: the Evolutionary Rate of HIV-1 Slows Down When the Epidemic Rate Increases

... and rate optimization, we also estimated the evolutionary rates of HIV-1 subtype A1 from the FSU and Africa by using Bayesian Evolutionary Analysis Sampling Trees (BEAST), a program for Bayesian ...

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The evolutionary rate variation among genes of HOG-signaling pathway in yeast genomes

The evolutionary rate variation among genes of HOG-signaling pathway in yeast genomes

... the evolutionary rate variation of the HOG path- way was correlated with codon bias, protein length and gene expression, suggesting that the genetic variation may be influenced by quite complicated ...

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Role of viral evolutionary rate in HIV 1 disease progression in a linked cohort

Role of viral evolutionary rate in HIV 1 disease progression in a linked cohort

... the evolutionary rates using a maximum likelihood framework that takes this into account and allows us to test different hypothe- ses using local clock models imposed onto the genealogy ...higher rate of ...

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Selection driven cost efficiency optimization of transcripts modulates gene evolutionary rate in bacteria

Selection driven cost efficiency optimization of transcripts modulates gene evolutionary rate in bacteria

... Given that codon choice has been shown to provide a selective advantage per codon per generation [27], it was hypothesized that the extent to which a transcript is jointly optimized for codon cost and efficiency would ...

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Competition Between the Sperm of a Single Male Can Increase the Evolutionary Rate of Haploid Expressed Genes

Competition Between the Sperm of a Single Male Can Increase the Evolutionary Rate of Haploid Expressed Genes

... at rate 2N m , where m is the mutation rate per generation per hap- loid ...mutation rate) should be defined as the expected number of mutations from the top ...

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Bottleneck Effect on Evolutionary Rate in the Nearly Neutral Mutation Model

Bottleneck Effect on Evolutionary Rate in the Nearly Neutral Mutation Model

... Thus, if bottlenecks occur in the nearly neutral mutation model, multiple substitutions occur in some lineages while very few substitutions occur in other lineages and [r] ...

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Functional Divergence in Tandemly Duplicated Arabidopsis thaliana Trypsin Inhibitor Genes

Functional Divergence in Tandemly Duplicated Arabidopsis thaliana Trypsin Inhibitor Genes

... the evolutionary rate of functionally important changes scription of herbivore-induced proteinase inhibitor on three levels in gene families: intraspecific diversity genes, we identified significant ...

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HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer

HIV Maintains an Evolving and Dispersed Population in Multiple Tissues during Suppressive Combined Antiretroviral Therapy in Individuals with Cancer

... the evolutionary rate of post-ART T cells compared with pre-cART plasma virus using a method similar to that described here, found that the evolutionary rate was reduced orders of mag- nitude ...

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Evidence that DNA repair genes, a family of tumor suppressor genes, are associated with evolution rate and size of genomes

Evidence that DNA repair genes, a family of tumor suppressor genes, are associated with evolution rate and size of genomes

... The literature was carefully searched for all animal species that can be characterized as living fossils (LF) (slow evolutionary rate) or radiated (R) (they have expe- rienced adaptive radiation). ...

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ICAM 1 related long non coding RNA: promoter analysis and expression in human retinal endothelial cells

ICAM 1 related long non coding RNA: promoter analysis and expression in human retinal endothelial cells

... Genomic evolutionary rate profiling (GERP) was per- formed using the Ensembl genome browser (Ensembl release 89—May 2017) [12] to identify evolutionarily con- strained elements across annotated eutherian ...

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Molecular Evolution of Hepatitis B Virus over 25 Years

Molecular Evolution of Hepatitis B Virus over 25 Years

... of evolutionary distance, and the topol- ogy was evaluated by bootstrap analysis (1,000 replicates) using the neighbor- joining ...on evolutionary distances ob- tained with the Tamura-Nei model for all ...

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Genetic History of Hepatitis C Virus in East Asia

Genetic History of Hepatitis C Virus in East Asia

... external rate calibra- tion approach previously employed by Pybus et ...the evolutionary rate of our 399-nt core gene fragment from an independent, previously published HCV data set (59) that does ...

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Human long intrinsically disordered protein regions are frequent targets of positive selection

Human long intrinsically disordered protein regions are frequent targets of positive selection

... Here we investigated the evolutionary pressures that may have acted on proteins containing long IDP regions in humans. Our approach differs from previous analyses of the evolutionary rate analysis of ...

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Predictable phenotypic, but not karyotypic, evolution of populations with contrasting initial history

Predictable phenotypic, but not karyotypic, evolution of populations with contrasting initial history

... the evolutionary history of populations is erased quickly, as selection seems to be more effective the farther the populations are from the phenotypic values and genetic frequencies of populations that have long ...

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s-0037-1603508.pdf

s-0037-1603508.pdf

... Next, we compared the evolutionary triangulation gene lists generated earlier to three separate gene lists. Sponta- neous PTB gene list 1 comprised the top 20 maternal and fetal SNPs from a multicenter genome-wide ...

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Estimation of Effective Population Size of HIV-1 Within a Host: A Pseudomaximum-Likelihood Approach

Estimation of Effective Population Size of HIV-1 Within a Host: A Pseudomaximum-Likelihood Approach

... the approach here over the full Bayesian strategy is ease of model checking. The first step of our procedure be- were sampled at the same time but sequence C was gins with reconstructing a geneaology and the structure ...

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