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ex vivo permeation studies.

Ketotifen fumarate and salbutamol sulphate combined transdermal patch formulations: In vitro release and Ex vivo permeation studies

Ketotifen fumarate and salbutamol sulphate combined transdermal patch formulations: In vitro release and Ex vivo permeation studies

... plastic tubes that connect the Franz cell with the thermostatic water bath (Brookfield, USA). The rabbit skin membrane was carefully placed over the open end of the receptor compartment. Patch of an area of 1.5 cm² was ...

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FORMULATION AND EVALUATION OF ELASTIC NIOSOMES OF ELETRIPTAN HYDROBROMIDE

FORMULATION AND EVALUATION OF ELASTIC NIOSOMES OF ELETRIPTAN HYDROBROMIDE

... upon ex-vivo permeation studies on rat abdominal skin, showed varied results because the elastic niosomal formulation containing Spans, Tweens and ethanol act as edge activators show effect on ...

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Journal of Applied Pharmaceutical Science

Journal of Applied Pharmaceutical Science

... Ex vivo permeation studies through porcine buccal mucosa The buccal epithelium was carefully mounted in between the two compartments of a Franz diffusion cell with an internal diameter (ID) of ...

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DESIGN OF OCULAR CONTROLLED RELEASE OCUSERTS OF BRINZOLAMIDE

DESIGN OF OCULAR CONTROLLED RELEASE OCUSERTS OF BRINZOLAMIDE

... Corneal Permeation Studies: The ex vivo permeation studies were carried out on optimized formulations using Franz diffusion ...

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Ex-vivo skin permeation studies of sumatriptan succinate using different solvent systems and its comparison with PLGA nanoparticles

Ex-vivo skin permeation studies of sumatriptan succinate using different solvent systems and its comparison with PLGA nanoparticles

... SS-NPs. Ex-vivo skin permeation studies of SS were conducted using distilled water, ethanol (EtOH), propylene glycol (PG), and their binary ...in ex-vivo permeation ...

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FORMULATION AND EVALUATION OF PHYTOCONSTITUENTS CREAM FOR THE TREATMENT OF VARICOSE VEINS

FORMULATION AND EVALUATION OF PHYTOCONSTITUENTS CREAM FOR THE TREATMENT OF VARICOSE VEINS

... and ex-vivo permeation studies were performed to estimate the diffusion of the drugs from the prepared ...from ex-vivo permeation studies that the flux for ...

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Design of transdermal patch of ketoprofen by full factorial design for treatment of rheumatoid arthritis

Design of transdermal patch of ketoprofen by full factorial design for treatment of rheumatoid arthritis

... nature. Ex vivo permeation studies concluded that permeation of drug from patch in different skin membrane up to ...Stability studies concluded that the patch retained its ...

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Optimization of Transmucosal Buccal Delivery of Losartan Potassium using Factorial Design

Optimization of Transmucosal Buccal Delivery of Losartan Potassium using Factorial Design

... K100M. Ex vivo permeation studies revealed that all films exhibited sustained release in the range of ...h. Ex vivo permeation studies through sheep buccal mucosa ...

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Fabrication and evaluation of selegiline HCl embedded transdermal film for management of Parkinson’s disease

Fabrication and evaluation of selegiline HCl embedded transdermal film for management of Parkinson’s disease

... on ex-vivo skin permeation of ...in ex-vivo permeation was observed with 20 % w/w of TEC of polymer ...in ex-vivo permeation ...

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Development and characterization of a nanoemulsion containing propranolol for topical delivery

Development and characterization of a nanoemulsion containing propranolol for topical delivery

... microscopy. Ex vivo permeation studies were used to evaluate the cutaneous retention of PPN in the epidermis and ...Cytotoxicity studies were performed in fibroblasts, macrophages, and ...

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FORMULATION AND EVALUATION OF NIFEDIPINE LOADED CHITOSAN MICROSPHERS FOR MUCOADHESIVE DRUG DELIVERY

FORMULATION AND EVALUATION OF NIFEDIPINE LOADED CHITOSAN MICROSPHERS FOR MUCOADHESIVE DRUG DELIVERY

... The ex-vivo permeation studies carried out by using porcine intestinal ...drug permeation is studied by using collection of receptor fluid at regular time intervals, and analysed for ...

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THERMOSENSITIVE GELS CONTAINING CARBAMAZEPINE MICROSPHERES FOR INTRANASAL BRAIN TARGETING

THERMOSENSITIVE GELS CONTAINING CARBAMAZEPINE MICROSPHERES FOR INTRANASAL BRAIN TARGETING

... vitro permeation and ex vivo ...Histopathological studies proved that the optimized formulation does not produce any toxic effect on the microscopic structure of nasal mucosa during ex ...

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Enhanced Iontophoretic Delivery of Sumatriptan Succinate from Thermosensitive Gel using Chemical Enhancers

Enhanced Iontophoretic Delivery of Sumatriptan Succinate from Thermosensitive Gel using Chemical Enhancers

... skin. Ex Vivo permeation studies of SS to study the effect of concentrations of PEG-400: As maximum flux was obtained with pulsed iontophoresis in combination with PEG- ...

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Development and Physicochemical, In Vitro and In Vivo Evaluation of Transdermal Patches of Zaleplon

Development and Physicochemical, In Vitro and In Vivo Evaluation of Transdermal Patches of Zaleplon

... physicochemical studies, in vitro release, ex vivo permeation studies through rat skin, skin irritation, stability and in vivo ...

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FEASIBILITY OF PALIPERIDONE FOR TRANSDERMAL THERAPEUTIC SYSTEMS: EX VIVO PERMEATION KINETIC STUDIES OF DRUG THROUGH RAT ABDOMINAL SKIN

FEASIBILITY OF PALIPERIDONE FOR TRANSDERMAL THERAPEUTIC SYSTEMS: EX VIVO PERMEATION KINETIC STUDIES OF DRUG THROUGH RAT ABDOMINAL SKIN

... pre-formulation studies was performed to authentication of the drug by determining the melting point, solubility, partition coefficient (PC), attenuated total reflection-Fourier transform infrared, differential ...

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Journal of Applied Pharmaceutical Science

Journal of Applied Pharmaceutical Science

... The Ex vivo residence time was determined by using modified physical balance ...on ex vivo mucoadhesion, ex vivo residence time and in-vitro release studies formulation F5 ...

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EFFECT OF PERMEATION ENHANCER ON EX VIVO PERMEATION OF ONDANSETRON HCl BUCCAL TABLETS

EFFECT OF PERMEATION ENHANCER ON EX VIVO PERMEATION OF ONDANSETRON HCl BUCCAL TABLETS

... Solubility studies: The solubility studies were conducted using pH 6.6 and pH 7.4 phosphate buffers which simulate the average pH values of oral cavity and blood respectively. An excess amount of drug was ...

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Skin models for the testing of transdermal drugs

Skin models for the testing of transdermal drugs

... skin permeation-enhancing properties and mechanism of action of the carrier systems, and estima- tion of rank of skin transport for a series of drug ...delivery studies has been focused on the use of ...

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Preparation and Evaluation of Matrix Type Transdermal Patches of Domperidone Maleate: in vitro and ex vivo Characterization

Preparation and Evaluation of Matrix Type Transdermal Patches of Domperidone Maleate: in vitro and ex vivo Characterization

... release studies showed that F2 formulation has higher drug release ...ing permeation enhancers F4 and F5 showed higher drug release ...and permeation enhancer ...

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Influence of freeze drying and ϒ-irradiation in pre-clinical studies of flurbiprofen polymeric nanoparticles for ocular delivery using D-(+)-trehalose and polyethylene glycol

Influence of freeze drying and ϒ-irradiation in pre-clinical studies of flurbiprofen polymeric nanoparticles for ocular delivery using D-(+)-trehalose and polyethylene glycol

... The ex vivo FB permeation from FB-P ε CL-NP formulations was evaluated using isolated pig cornea and sclera using Franz-type diffusion cells. Fresh pig eyes were obtained from adult male pigs ...

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