Expression of Cyclin A
Sequential activation of cyclin E and cyclin A gene expression by human papillomavirus type 16 E7 through sequences necessary for transformation.
... of cyclin gene expression by conserved domains 2 and 1 of HPV-16 ...of cyclin E gene expression in NIH 3T3 cells, in the absence of growth factors, is dependent on cd2 but does not require cd1 ...
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Expression of Cyclin A in Rectal Mucosa and Rectal Carcinoma.
... and cyclin A ...0.002). Cyclin A expression was found in 98% of all biopsies, with a higher number of immunopositive cells in group A biopsies (P = ...and cyclin A expression may help ...
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An analysis of Cyclin D1, Cytokeratin 5/6 and Cytokeratin 8/18 expression in breast papillomas and papillary carcinomas
... 5/6. Cyclin D1 over-expression leads to the sustained proliferation of mammary epithelial cells, which is associated with a delay in acinar development in vitro models [27] and a failure to undergo terminal ...
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Cyclin D1 Expression in Laryngeal Cancer.
... Over expression of Cyclin D1 correlates with recurrence in a group of forty-seven operable squamous cell carcinomas of the head and neck, Cancer ...protein expression with lymph node metastases and ...
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Original Article Does cyclin E and p57 kıp2 expression have prognostic and survival value in colorectal adenocarcinoma?
... low- expression group for cyclin E. The relation between cyclin E expression level and age, gen- der, lymphovascular invasion, perineural invasion, histologi- cal grade, depth of invasion, ...
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<p>Expression Of Cyclin D1 Protein Isoforms And Its Prognostic Significance In Cervical Cancer</p>
... the expression of cyclin D1 and its splice variants cyclin D1a and cyclin D1b, which arise from a single-nucleotide polymorphism in the CCND1 gene in cervical ...While cyclin D1 has ...
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Cyclin D1 expression in colorectal cancer is a favorable prognostic factor in men but not in women in a prospective, population-based cohort study
... of cyclin D1 expression and relevant clinicopatholo- gical ...to cyclin D1 ...to cyclin D1 expression in both univariate and multivariate analyses, adjusted for age, gender, TNM stage, ...
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Original Article Upregulation of ATF-3 is correlated with prognosis and proliferation of laryngeal cancer by regulating Cyclin D1 expression
... showed Cyclin D1 level decreased in LSCC cells after ATF-3 gene ...ing Cyclin D1 related ...of Cyclin D1 sig- nal ...decreases Cyclin D1 expression in Hep-2 ...
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Analysis of cyclin A expression in cells with a finite mitotic lifespan
... whereas cyclin E primarily associates later in 01 with CDK2 (Dulic, Lees, and Reed, 1992; Koff et a l, ...D-type cyclin which are in part cell type specific with most cells expressing D3 and either D1 or D2 ...
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Immunohistochmical Expression of Cyclin D1 Protein in Sudanese patients with thyroid cancer
... of cyclin D1 depend on prognostic parameters such as age, sex and tumor size which the cyclin D1 expression were included in the univariate analysis to determinethe thyroid cancer univariate analysis ...
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Expression of Cyclin D1 in normal and hyperplastic endometrium
... in expression of cyclin D1 both in terms of extent as well as intensity of staining between normal secretory and proliferative phase endometrium versus endometrial ...The expression of cyclin ...
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Cyclin D1 and p16 expression in recurrent nasopharyngeal carcinoma
... of expression of cyclin D1 and p16 in cancer with ...proto-oncogene cyclin D1 with worse prognosis in terms of shorter survival and increased incidence of recurrence ...over-expressing cyclin ...
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Adenovirus E1B55K Region Is Required To Enhance Cyclin E Expression for Efficient Viral DNA Replication
... of cyclin E protein in A549 cancer cells. The role of cyclin E in tumor- igenesis has recently been investigated (51, ...produce cyclin E or can be induced to over- express cyclin E by the ...
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Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression
... CCNE1 expression stimulates cell proliferation [6] and increases colony formation ...CCNE1 expression, developing small molecules to target CCNE1 directly is unlikely because CCNE1 acts as a regulatory ...
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Modulation of cyclin gene expression by adenovirus E1A in a cell line with E1A-dependent conditional proliferation.
... As already suggested by the rapid induction of cyclin E mRNA upon activation of ElA-ER in IREE-1 cells, these data indicate that EIA acts as a potent inducer of cyclin E gene expression,[r] ...
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Antimitogenic effects of HDL and APOE mediated by Cox 2–dependent IP activation
... inhibits cyclin A gene expression via pocket protein– dependent and independent ...of cyclin A regulates entry of cells into S-phase, the effect of APOE on cyclin A expression and ...
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Original Article Synergistic effects of AKAP95, Cyclin D1, Cyclin E1, and Cx43 in the development of rectal cancer
... [16-18]. Cyclin D1 and Cyclin E1 are two proteins that regulate the G1 to S phase progression in mitotic cells; these two proteins are mainly over-expressed in cancer tissues [4-6]; in addition, ...
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WWC3 downregulation correlates with poor prognosis and inhibition of Hippo signaling in human gastric cancer
... protein expression was downregulated in GC cell lines compared with normal cell line ...repressed cyclin D1 and cyclin E while upregulated p27 ...
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Cyclin-Dependent Kinase 1/Cyclin B1 Phosphorylates Varicella-Zoster Virus IE62 and Is Incorporated into Virions
... atypical expression of cyclins D3 and B1 occurs along with the induction of cyclin-dependent kinase (CDK) ...of cyclin B1 from VZV-infected HFFs indicated that IE62 was included in the complex within ...
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Clinical significance and biological roles of cyclins in gastric cancer
... The expression levels of CCNA2 (cyclin A2), CCNB1 (cyclin B1), CCNB2 (cyclin B2), and CCNE1 (cyclin E1) mRNAs were identified to be significantly higher in GC tissues than in normal ...
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