Extracellular Matrix
TEM and SEM observations on the extracellular matrix of the developing murine centra
... the extracellular matrix (ECM). During day 15 GA, typical matrix vesicles with crystalline contents appeared, as followed by single and fusing pleomorphic aggregates of a more regular crystal- line ...
9
Clara cell adhesion and migration to extracellular matrix
... the extracellular matrix during injury may regulate the Clara cell proliferative ...of matrix substrates on Clara cell proliferation, freshly isolated Clara cells were plated on chamber slides that ...
11
Endothelial cell response to artificial extracellular matrix proteins
... Artificial extracellular matrix (aECM) proteins were designed originally for use in small-diameter vascular grafts. Current synthetic grafts fail primarily due to (i) a compliance mismatch between the ...
17
Imbalance in extracellular matrix degradation in urethral stricture
... percentage of type I collagen between the two groups. MMPs are very important enzymes, due to their function in the development of healthy tissue, especially in remodeling the extracellular matrix. The main ...
6
Extracellular matrix motion and early morphogenesis
... static extracellular matrix (ECM) requires serious rethinking given recent evidence showing ECM motion during early amniote embryogenesis (discussed ...
10
Influence of substrate curvature on osteoblast orientation and extracellular matrix deposition
... The goal of this study was to determine osteoblast response to being cultured on a curved substrate mimick- ing the native curvature of an osteon. This was investi- gated through the alignment of cells in the ...
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Extracellular matrix modifications at fertilization: regulation of dityrosine crosslinking by transamidation
... Four major enzymatic activities are essential for the proper assembly of the fertilization envelope: proteolysis, transamidation, hydrogen peroxide synthesis and peroxidase-dependent dityrosine crosslinking. The serine ...
13
The extracellular matrix as a cell cycle control element in atherosclerosis and restenosis
... vSMC extracellular matrix and/or the integrins that are expressed by vSMCs may therefore affect MAP kinase activity, cyclin D1 expression, pRb phosphorylation and, ultimately, cell prolifer- ...
5
Extracellular Matrix and Control of Proliferation of Vascular Endothelial Cells
... The ability of plasma vs. serum to sustain cell proliferation was analyzed using low density bovine-vascular endothelial cell cultures maintained either on plastic or on dishes coated with an extracellular ...
15
Extracellular matrix production in vitro in cartilage tissue engineering
... Different coatings of cell culture surfaces influences chondrocyte culture in vitro. Cells cultured on collagen type I and II coating dishes expressed more collagen type II expression and produced more glycosaminogly- ...
9
The nature and functional significance of dentin extracellular matrix proteins
... Int J II lIi"t 39 169 179 ( 1995) The nature and functional significance of dentin extracellular matrix proteins WilLIAM T BUTLER' and HELENARITCHIE Department of Basic Sciences The University of Texa[.] ...
11
Fibrotic extracellular matrix activates a profibrotic positive feedback loop
... Pathological remodeling of the extracellular matrix (ECM) by fibroblasts leads to organ failure. Development of idiopathic pulmonary fibrosis (IPF) is characterized by a progressive fibrotic scarring in the ...
15
Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix
... The Hedgehog (Hh) family of morphogenetic proteins has important instructional roles in metazoan development. Despite Hh being modified by Ct-cholesterol and Nt-palmitate adducts, Hh migrates far from its site of ...
13
Disruption of the myocardial extracellular matrix leads to cardiac dysfunction
... Congestive heart failure (CHF) is an important and rapidly growing cause of mortality and morbidity in the United States. Approximately 25,000 people die from CHF, with more than 875,000 hospitalizations annually in the ...
11
The extracellular matrix in myocardial injury, repair, and remodeling
... of extracellular matrix (ECM) ...interstitial matrix and with marked alterations in its composition (2, 3); these changes perturb cardiac systolic and diastolic ...and matrix debris, ...
14
Extracellular matrix hydrogels from decellularized tissues: structure and function
... [25] Bible E, Dell'Acqua F, Solanky B, Balducci A, Crapo PM, Badylak SF, Ahrens ET, Modo M. Non-invasive imaging of transplanted human neural stem cells and ECM scaffold remodeling in the stroke-damaged rat brain by ...
46
The congenital clubfoot – immunohistological analysis of the extracellular matrix
... the extracellular matrix (ECM; based on common interstitial collagens [C] like CI and CIII, microfilamentous collagens like CVI, noncollagenous proteins like undulin, and enzymes like ...
8
The effect on the extracellular matrix of the deep fascia in response to leg lengthening
... the extracellular matrix in normal, embryonic, or tumor tissues, in our study, a strong staining with Alcian blue in both control and dis- tracted fascias indicated the presence of chondroitin sul- phate ...
5
Expression of CD133 and Extracellular Matrix Molecules in Malignant Brain Tumors
... In the previous study, we have demonstrate that EGFR and MT1-MMP were immunostained predominantly in brain metastasis [13]. The high expression of EGFR and MT1-MMP indicates that an extracellular matrix ...
5
Integrins and vascular extracellular matrix assembly
... Angiogenesis, the formation of new blood vessels, also has im- portant connections to integrins and the matrix. Endothelial cells migrate on extracellular matrix components in vitro and very likely ...
5