F Protein
Roles of the Putative Integrin-Binding Motif of the Human Metapneumovirus Fusion (F) Protein in Cell-Cell Fusion, Viral Infectivity, and Pathogenesis
... hMPV F pro- tein-induced cell-cell ...hMPV F protein-mediated cell-cell ...hMPV F protein. Briefly, Vero E6 cells were transfected with pCAGGS-F, followed by incubation with ...
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Newcastle Disease Virus HN Protein Alters the Conformation of the F Protein at Cell Surfaces
... cleaved F protein expressed ...uncleaved F protein on cell ...cleaved F protein was accessible to anti-HR1 binding. Cleaved F protein in the presence of HN ...
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Amino Acid Substitutions in the F-Specific Domain in the Stalk of the Newcastle Disease Virus HN Protein Modulate Fusion and Interfere with Its Interaction with the F Protein
... (HN) protein of Newcastle disease virus mediates attachment to sialic acid receptors, as well as cleavage of the same ...(F) protein, to promote membrane ...HN protein to interact with ...
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Hepatitis C Virus F Protein Is a Short-Lived Protein Associated with the Endoplasmic Reticulum
... the F protein, we have expressed the F protein of the HCV-1 isolate in Huh7 cells, a well-differentiated human hepatoma cell ...core protein to the ⫺2/⫹1 reading frame. Hence, the ...
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The Cytoplasmic Tail of the Human Respiratory Syncytial Virus F Protein Plays Critical Roles in Cellular Localization of the F Protein and Infectious Progeny Production
... between F protein and other viral components during ...virus F and human immunodeficiency virus type 1 Env proteins, the CT is thought to interact with the viral matrix protein (37, ...matrix ...
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Identification of Domains on the Fusion (F) Protein Trimer That Influence the Hemagglutinin-Neuraminidase Specificity of the F Protein in Mediating Cell-Cell Fusion
... the F protein ...HN protein of HPIV2 or SV41, which includes the 53 membrane proximal amino acids of the stalk region, determines the specificity for the homolo- gous F protein in ...
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Ubiquitin-Independent Degradation of Hepatitis C Virus F Protein
... the F protein. The F-protein coding sequence of the HCV-1 isolate was generated by deleting an adenosine residue from codon 10 of the core protein sequence to mimic a ⫹ 1 ribosomal ...
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Development of a Recombinant Based ELISA using Specific Antibodies to F Protein in HCV Chronically Infected Patients-A Seroprevalence Study
... aa protein (13, ...for F protein in pathogenesis of HCV. It has been shown that F is expressed at high level in advanced stages of disease and cancer ...against F protein, the ...
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Identification of Residues in the Human Respiratory Syncytial Virus Fusion Protein That Modulate Fusion Activity and Pathogenesis
... F protein total and surface expression ...each F construct in the presence of BMS-433771 RSV F ...RSV F-specific monoclonal antibody, motavizumab (generously provided by Nancy Ul- ...
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The Paramyxovirus Fusion Protein C-Terminal Region: Mutagenesis Indicates an Indivisible Protein Unit
... the F protein C terminus, and they may have independent functions in regulating fusion ...PIV5 F protein back into the C terminus chimeras. First, the PIV5 F cy- toplasmic tail was put ...
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A Novel Influenza Virus Hemagglutinin-Respiratory Syncytial Virus (RSV) Fusion Protein Subunit Vaccine against Influenza and RSV
... F protein provides cross-protective antibody ...with F protein alone had reduced X31 lung titers relative to the control mice ...that F protein may induce cross-reactive ...
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Endocytosis Plays a Critical Role in Proteolytic Processing of the Hendra Virus Fusion Protein
... virus F proteins were metabolically labeled for 2 h, chased for 1 h, and then biotinylated with the reducible agent sulfo-NHS-SS- ...virus F protein was rapidly endocytosed, with ⬎ 60% of the ...
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Evolution of Bovine Respiratory Syncytial Virus
... G protein fragment, to arbitrarily divide the data into six subgroups (I to VI) ...and F protein genes (Fig. 2 and 3). In this case, as for the G protein gene, the topology and significance of ...
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Cathepsin L Is Involved in Proteolytic Processing of the Hendra Virus Fusion Protein
... virus F cleavage ...virus F proteins ...virus F process- ...virus F protein processing (19), the addition of the metalloprotease inhibitors GM6001 and 1,10-phenanthro- line ...SV5 ...
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Mills_unc_0153D_17509.pdf
... Cyclin F targets to date include Centriolar coiled-coil protein of 110 kDa (CP110), which is involved in centrosome duplication, an event important for bipolar spindle establishment during mitosis (81, ...
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Expression of the fusion protein of human respiratory syncytial virus from recombinant vaccinia virus vectors and protection of vaccinated mice.
... We describe the analysis of F protein expression in infected cells and the ability of the recombinant vectors expressing F protein to protect the lungs of immunized mice against live RS [r] ...
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A Cellular Drosophila melanogaster Protein with Similarity to Baculovirus F Envelope Fusion Proteins
... of f and/or gp64 in various subgroups within the family is the following: ancestral baculoviruses may have replicated only in the epithelial cells of the insect midgut, producing only occlusion derived virions and ...
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Atypical Measles Syndrome: Pathologic and Serologic Findings
... infection requires antibodies against the F protein, and explains why children who received the killed vaccine, which does not induce antibodies to the F protein,9 would be also unable t[r] ...
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The F-Like Protein Ac23 Enhances the Infectivity of the Budded Virus of gp64-Null Autographa californica Multinucleocapsid Nucleopolyhedrovirus Pseudotyped with Baculovirus Envelope Fusion Protein F
... contain F-like pro- teins, such as those encoded by Ac23 from Autographa califor- nica multinucleocapsid NPV (AcMNPV) (7) and Op21 from Orgyia pseudotsugata MNPV ...These F-like proteins coexist with GP64 ...
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The Transmembrane Domain Sequence Affects the Structure and Function of the Newcastle Disease Virus Fusion Protein
... NDV F protein expressed alone. It also binds to F protein coexpressed with the NDV HN protein if the attachment of HN protein is blocked by the incubation of cells in ...
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