Fas cell surface death receptor
Original Article Identification of genes associated with apoptosis-sensitive acute lymphoblastic leukemia responsive to ionising radiation by bioinformatics analyses
... and Fas cell surface death receptor (FAS), were mainly enriched in the BP terms related to apoptosis and p53 signaling ...TNF receptor superfamily member 5 (CD40) were ...
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The Adenovirus E3 RID Complex Protects Some Cultured Human T and B Lymphocytes from Fas-Induced Apoptosis
... virus-infected cell, including the E3 receptor internalization and degradation (RID) ...prevents death of infected cells by blocking apoptosis initiated through death domain-containing ...
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Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells
... (DN) FAS-Associated protein with Death Domain (FADD), Bcl2 or Cytokine response modifier A (CrmA) blocked caspase-8 cleavage, subsequent mitochon- drial depolarisation and caspase-9 activation in these ...
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The adenovirus E3-10.4K/14.5K complex mediates loss of cell surface Fas (CD95) and resistance to Fas-induced apoptosis.
... use Fas (CD95), a member of the tumor necrosis factor (TNF) receptor superfamily, to eliminate virus-infected cells by activation of the apoptotic pathway for cell ...TNF-dependent cell ...
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CD74 interferes with the expression of fas receptor on the surface of lymphoma cells
... first cell lines with stable knock-down of CD74 expression by lentiviral and episomal vectors expressing CD74-targeting shRNA (Figure ...these cell lines, we showed that removal of CD74 sensitizes cells to ...
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Looking beneath the Surface: The Cell Death Pathway of Fas/APO-1 (CD95)
... (1994a) Identification of a protein kinase associated with the cytoplasmic domain of the p60 tumor necrosis factor receptor. Darnay BG, Singh S, Chaturvedi MM, Ag-[r] ...
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The Relative Role of Lymphocyte Granule Exocytosis versus Death Receptor-Mediated Cytotoxicity in Viral Pathophysiology
... accelerate Fas-mediated, activation- induced T-cell apoptosis ...of Fas on T cells in individuals with HIV infection (91), leading many to believe that HIV destroys immune cells via the ...
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Camptothecin induces the transit of FasL trimers to the cell surface in apoptotic HEp-2 cells
... co-express Fas and FasL without suffering spontaneous apoptosis, for example the MDCK cells in which Fas and FasL are segregated into different cellular compartments ...the Fas receptor which ...
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Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes A potential role for the acidic sphingomyelinase pathway in normal immunoregulation
... of Fas (CD95 / APO-1), a cell surface receptor directly responsible for triggering cell death by apoptosis, was investigated on human T lympho- cytes resident within the ...
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Critical role for BIM in T cell receptor restimulation-induced death
... "activation-induced cell death (AICD)" ...antigen receptor that causes rest- ing cells to cycle, expand, and acquire effector function – and the death mechanism induced by TCR ...
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The contrasting roles of IL 2 and IL 15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases
... two receptor subunits and some functions, they also provide distinct and at times contrasting contributions to the life and death of lymphocytes ...in Fas-mediated activation-induced cell ...
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Consequences of cellular cholesterol accumulation: basic concepts and physiological implications
... integral membrane proteins whose func- tion is blocked or altered under conditions of high membrane rigidity. This and sever- al other models for FC-induced cell death, discussed below, are summarized in ...
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A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma
... Toll-like receptor signaling pathway [43], the inflammasome pathway [44–47], the TNFα pathway [22, 23, 48–50], and the complement cascade ...the Fas receptor is best known for inducing apoptosis ...
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TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment
... tumor cell-host cell interactions in the bone microenvironment and of autocrine and paracrine effects of the se- creted (from tumor cells) and released (from bone matrix) factors which may facilitate the ...
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Stretch induced programmed myocyte cell death
... programmed cell death, superoxide anion formation, the expression of Fas on myocytes, and side-to-side slippage of myocytes, papillary muscles were exposed to 7-8 and 50 mN/mm2 and these parameters ...
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Effects of controlled diesel exhaust exposure on apoptosis and proliferation markers in bronchial epithelium – an in vivo bronchoscopy study on asthmatics, rhinitics and healthy subjects
... Whilst none of the examined markers were altered in the asthmatics or allergic rhinitics after exposure to DE, this study is the first to report an in vivo effect of DE exposure on Bcl-2 expression in healthy subjects. ...
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Houttuynia cordata Thunb extract modulates G0/G1 arrest and Fas/CD95-mediated death receptor apoptotic cell death in human lung cancer A549 cells
... of cell cycle arrest and/or apoptosis in lung cancer cells has been considered an influential treatment strategy ...reducing cell number through the induc- tion of cell cycle arrest and apoptosis ...
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Deregulation of the Egfr/Ras signaling pathway induces age-related brain degeneration in the Drosophila mutant vap
... neuronal cell death (reviewed in Fortini and Bonini, ...in cell culture, the withdrawal of these factors or blocking their signal transduction pathways leads to cell death (Barres et ...
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Apoptosis and the FLIP and NF-kappa B proteins as pharmacodynamic criteria for biosimilar TNF-alpha antagonists
... a Fas- associated death domain protein and Fas is a death receptor [also known as CD95 and ...the death-inducing signaling complex (DISC) and thereby inhibiting ...
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PKCε stimulates vesicular exocytosis of α7 nicotinic ach receptor by targeting nsf
... Immunoprecipitation and Western blotting: PC-12 cells, treated with dimethyl sulfoxide (DMSO) [0.1% (v/v)] or DCP- LA (100 nM) for 10 min, were homogenized by sonication in TBS-T [150 mM NaCl, 0.1% (v/v) Tween-20 and 20 ...
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