FAS, fatty acid synthase
Targeting adipose tissue
... Agency; FAS: fatty acid synthase; FDG: 2- deoxy-2[ 18 F]fluoro-D-glucose; FFA: free fatty acids; Fndc5: fibronectin type III domain containing 5; GC: guanylate cyclase; GLUT: glucose ...
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Transcriptome and gene expression analysis of docosahexaenoic acid producer Schizochytrium sp. under different oxygen supply conditions
... for fatty acid biosynthesis in Schizochytrium sp., a fatty acid synthase (FAS) pathway, and a polyunsaturated fatty acid synthase pathway (PKS) ...the ...
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AMPK -1 , and lower APOB gene expression in the liver than 42-day-old broilers. Age had no effect on FAS gene expression. Our results show that the gender and age could act on the expression of genes related to
... of fatty acid synthase (FAS), apolipoprotein A-I (APOA-I), apolipoprotein B (APOB), adiponectin (ADIPOQ), liver kinase B1 (LKB1), and AMP-activated protein kinase α-1 (AMPKα-1) genes was ...
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Fatty Acid Synthase Inhibitor C75 Ameliorates Experimental Colitis
... We have further examined other path- ways that contribute to the development of colitis. Elevation of MDA levels in the inflamed colon are significantly sup- pressed by C75 treatment. MDA low- molecular-weight end ...
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Effect of cerulenin on fatty acid composition and gene expression pattern of DHA-producing strain Colwellia psychrerythraea strain 34H
... conventional fatty acid desaturase/ elongase pathway in algae and ...20 fatty acid desaturases and fatty acid elongases involved in this process ...polyketide synthase ...
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<p>Lipid metabolism in chronic obstructive pulmonary disease</p>
... glycolysis, FAS and ...tricarboxylic acid (TCA) ...(ACC1). Fatty acid synthase (FAS) performs the condensation of acetyl-CoA and malonyl-CoA to produce the 16-carbon saturated ...
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CircRNAs in cancer metabolism: a review
... FA: Fatty acid; FAO: Fatty acid β -oxidation; FAS: Fatty acid synthesis; FASN: Fatty acid synthase; GLUT: Glucose transporter; HCC: Hepatocellular ...
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Impact of dietary protein on lipid metabolism-related gene expression in porcine adipose tissue
... (ACC), fatty acid synthase (FAS), malic enzyme (ME) and glucose-6-phosphate dehydrogenase (G-6-PDH), and changes in their activities can alter the rates of bio- synthesis of fatty acids ...
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Dietary supplement of Smilax china L. ethanol extract alleviates the lipid accumulation by activating AMPK pathways in high-fat diet fed mice
... of fatty acid synthase (FAS) and AMP-activated protein kinase (AMPK) ...ACO, FAS and AMPK in the liver were determined by the method of Zhao et al ...
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Terminalia paniculata bark extract attenuates non-alcoholic fatty liver via down regulation of fatty acid synthase in high fat diet-fed obese rats
... induced drop in the activity of SOD and CAT but ele- vated MDA content was noted in HFD-fed rats. But in HFD + TPEE (100, 150 and 200 mg/kg b.wt) adminis- tered rats, raise in SOD and CAT activity but fall in MDA level ...
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The Korean herbal medicine, Do In Seung Gi Tang, attenuates atherosclerosis via AMPK in high fat diet induced ApoE−/− mice
... Mice were deeply anesthetized with sodium thiopental and subsequently perfused with cold PBS, followed by fixation with 10 % (w/v) paraformaldehyde overnight. Hematoxylin and Eosin (H&E): Livers were embedded in ...
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Involvement of gut microbial fermentation in the metabolic alterations occurring in n-3 polyunsaturated fatty acids-depleted mice
... of fatty acid synthase (FAS)-the rate-limiting enzyme for lipid synth- esis-was decreased, whereas carnitine palmitoyl transfer- ase 1 (CPT1) and peroxisome proliferator-activated receptor ...
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The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice
... of fatty acid translo- case (CD36), fatty acid synthase (FAS), adipocyte fatty acid-binding protein (aP2), acetyl-CoA carboxylase 1 (ACC1) and stearoyl-CoA ...
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Increasing medium chain fatty acids production in Yarrowia lipolytica by metabolic engineering
... Cellular fatty acids are derived from three different sources: endogenous lipid turnover, de novo synthesis and elongation, and external ...solic fatty acid synthase (FAS) catalyzes de ...
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An engineered fatty acid synthase combined with a carboxylic acid reductase enables de novo production of 1-octanol in Saccharomyces cerevisiae
... noic acid) in buffered medium overlaid with 20% dode- cane confirmed the partial accumulation of octanoic acid in the organic phase ...octanoic acid production is necessary to compensate the loss of ...
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Involvement of fatty acid synthase in dengue virus infection
... of fatty acid synthase (FASN; a critical rate limiting enzyme in lipid biosynthesis) to the replication complex by interaction with DENV NS3 has been reported [25, ...
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Original Article Cerulenin induces apoptosis in hepatic cancer HepG2 cells in vitro and in vivo
... Abstract: Cerulenin is believed to play an anti-tumor role in several types of cancers, but its impact on hepatic cancer is not fully clarified. In this study, the growth inhibitory effect of cerulenin on hepatic cancer ...
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Update on human genome completion and annotations: Gene nomenclature
... short-chain fatty acid synthase and a novel cytosolic long-chain fatty acid ...chain fatty acid synthase, which include mouse and rat Fasn, and 12 loci for ...
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Metabolic engineering of microbes for branched-chain biodiesel production with low-temperature property
... to fatty acid methyl esters (FAMEs) or ...presented fatty acid short-chain ester (FASE) biosynthesis as an improvement of the low- temperature properties of traditional ...of fatty ...
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Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation
... Epidermal growth factor receptor (EGFR) is an oncogenic receptor tyrosine kinase. Canonically, the tyrosine kinase activity of EGFR is regulated by its extracellular ligands. However, ligand-independent activation of ...
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