Fas mediated apoptosis
Tolerance induction ameliorates allograft vasculopathy in rat aortic transplants Influence of Fas mediated apoptosis
... cells, apoptosis, and Fas–Fas ligand ...fewer Fas- and FasL-expressing ...lografts. Fas expression was found in T cells, macrophages, vascular smooth muscle cells, and endothelial ...
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Stimulated human lamina propria T cells manifest enhanced Fas mediated apoptosis
... of apoptosis in LP T cells, we showed in a previous study that while unstimulated and com- parable PB and LP T cell populations (CD45R01 cells) ex- pressed equal amount of Fas only the LP T cells are ...
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MicroRNA 196B regulates FAS-mediated apoptosis in colorectal cancer cells
... the FAS-mediated apoptosis pathway and thus an attractive target in cancer ...therapy. FAS mAbs could act as effective anticancer agents by activating FAS-mediated ...
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Fas mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis
... of apoptosis/activation-induced cell death (AICD) in the spontaneous recovery from acute ...in Fas (CD95/APO-1)–deficient SJL lpr/lpr mice, which displayed significantly increased mean peak clinical scores, ...
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The role of interleukin converting enzyme in Fas mediated apoptosis in HIV 1 infection
... as Fas-R or ...of apoptosis in CD4 1 cells has been demonstrated recently using a specific ICE inhibitor, while apoptosis of CD8 1 lymphocytes was inhibited by an inhibitor of CPP32, an ICE-related ...
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Monocytes Regulate the Mechanism of T-cell Death by Inducing Fas-Mediated Apoptosis during Bacterial Infection
... The D6 mutation refers to deletion of amino acid residues A146 and R147 from pneumolysin, introduced by site-directed mutagen- esis [47]. The altered gene replaced the chromosomal gene [48]. The Janus cassette, which ...
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Original Article Distinct different sensitivity of Treg and Th17 cells to Fas-mediated apoptosis signaling in patients with acute coronary syndrome
... to Fas-mediated apoptosis which could lead to Th17/Treg imbalance in ACS ...the apoptosis of Th17 and Treg cells, apop- tosis-related Fas/Fas ligand(FasL) pathway, and ...
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Fibroblast growth factor 21 inhibits atherosclerosis in apoE−/− mice by ameliorating Fas-mediated apoptosis
... stress-mediated apoptosis, and this mechanism of FGF21 is different from that found in our ...on Fas/ FADD-mediated ...HUVEC apoptosis model to study the signaling ...
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Metabolic state alteration of neural stem cells controls FAS mediated apoptosis and neurogenesis
... treatment, Fas (PE conjugated hamster anti- Mouse CD95), IsoFas (PE anti-Armenian and Syrian ham- ster IgG cocktail), Fas Ligand (PE labeled anti-Mouse CD178), IsoFas Ligand (PE Rat IgG2bk isotype control) ...
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Highly efficient, In-vivo Fas-mediated Apoptosis of B-cell Lymphoma by Hexameric CTLA4-FasL
... In agreement with tumor volume and the survival in- dexes, the high efficacy of CTLA4-FasL treatment of JY xenograft tumors was further illustrated by the immuno- staining of tumors removed from the mice, with anti- ...
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PubMedCentral-PMC4901134.pdf
... that Fas-mediated apoptosis indeed plays a critical role in the pathogenesis of alcoholic liver disease and that deletion of FasL permits a more regulatory/wound healing pattern that promotes fi ...
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Epstein-Barr Virus-Encoded Poly(A)− RNA Confers Resistance to Apoptosis Mediated through Fas by Blocking the PKR Pathway in Human Epithelial Intestine 407 Cells
... During apoptosis, PARP is cleaved from its intact form (110 kDa) into 85-kDa and 25-kDa fragments ...antagonize Fas- induced apoptosis via their viral ...from Fas-mediated ...
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CpG oligonucleotides suppress HepG2 cells-induced Jurkat cell apoptosis via the Fas-FasL-mediated pathway
... of Fas in the tumor pro- gression and metastasis, the Fas-mediated apoptosis might be a target for cancer ...related apoptosis-inducing ligand receptor (TRAIL) can modulate the ...
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Butyric Acid-Induced T-Cell Apoptosis Is Mediated by Caspase-8 and -9 Activation in a Fas-Independent Manner
... induced apoptosis in murine thymocytes, splenic T cells, and human Jurkat ...T-cell apoptosis. Flow cytometry analysis indicated that expression of Fas in Jurkat and T cells from peripheral blood ...
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Therapeutic effect of the anti Fas antibody on arthritis in HTLV 1 tax transgenic mice
... demonstrated Fas-mediated apoptosis in the synovium of patients with rheumatoid arthritis (RA) and suggested that it may be one factor responsible for the regression of ...anti- Fas mAb into ...
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Childhood Polyarteritis Nodosa in Autoimmune Lymphoproliferative Syndrome
... of Fas-mediated apoptosis that results in impaired lympho- cyte death and, therefore, disturbed immune ...in Fas-deficient mouse models that frequently develop vasculitic manifestations and ...
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Hepatitis C Virus Core Protein Leads to Immune Suppression and Liver Damage in a Transgenic Murine Model
... possibly mediated by an impaired immune response to HCV ...to Fas-mediated ...to Fas-deficient lpr ...increasing Fas-mediated apoptosis and liver infiltration of ...
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Oxidized LDL activates fas mediated endothelial cell apoptosis
... to Fas-mediated apoptosis, although they express detectable Fas on their cell surface ...trast, Fas ligand can readily induce apoptosis in Fas-bearing vascular smooth ...
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Hepatitis B Spliced Protein (HBSP) Suppresses Fas-Mediated Hepatocyte Apoptosis via Activation of PI3K/Akt Signaling
... inhibited Fas-mediated apoptosis of hepatoma cells via downregulation of Fas, p53, and FasL (53), whereas another study reported that the core protein impaired the phosphorylation of ...
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Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS- mediated death signaling in human ovarian granulosa tumor cells
... to FAS-mediated apoptosis via a receptor mechanism [64, ...increased FAS expression and enhanced sensitivity to FasAb-induced apoptosis is consistent with evidence that shows knockdown ...
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