FAT/CD36
CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions
... and FAT/CD36-null mice subjected for ...and FAT/CD36-null mice subjected to a choice between a 5% linoleic acid– or paraffin oil–enriched diet for 1 ...
9
Original Article Hepatic fat accumulation and regulation of FAT/CD36: an effect of hepatic irradiation
... affect fat metabolic pathways. The current study investi- gates hepatic fat accumulation and fatty acid transportation in a rat model of single dose liver irradiation ...in FAT/CD36 expres- ...
14
Heart CD36 expression is increased in murine models of diabetes and in mice fed a high fat diet
... of CD36 expression are found in triglyceride storing and secreting cells such as differentiated adipocytes and mammary secretory epithelial cells and in some capillary endothelial ...of CD36 in the ...
8
Betaine affects muscle lipid metabolism via regulating the fatty acid uptake and oxidation in finishing pig
... Results: Betaine addition to the diet significantly increased the concentration of free fatty acids (FFA) in muscle (P < 0.05). Furthermore, the levels of serum cholesterol and high-density lipoprotein cholesterol ...
9
Review: Omega-3 fatty acids transport through the placenta
... Abstract: The placenta is a temporary vital organ for sustaining the development of the fetus throughout gestation. Although the fatty acid composition delivered to the fetus is largely determined by maternal circulating ...
8
Metformin regulates lipid metabolism in a canine model of atrial fibrillation through AMPK/PPAR-α/VLCAD pathway
... Circulating FAs enter into cardiomyocytes via the FA transporter FAT/CD36 and then entry into mitochondria for FA oxidation through Carnitine palmitoyl transferase-1 (CPT-1). The mitochondrial fatty acid ...
9
Piperine enhances carbohydrate/fat metabolism in skeletal muscle during acute exercise in mice
... both fat and carbohydrates must be activated simultaneously ...that FAT/CD36, CPT1, and CS are key components of the molecular ma- chinery required for regulating fat oxidation in skeletal ...
8
CD36 tango in cancer: signaling pathways and functions
... acids; FAT, fatty acid translocase; FoxO1, forkhead box O1; GAS, interferon-gamma activated sequence; GBM, glioblastoma; GM-CSF, granulocyte-macrophage colony-stimulating factor; GP, glycoprotein; GSK-3, glycogen ...
16
Parkin is a lipid responsive regulator of fat uptake in mice and mutant human cells
... in fat uptake was confirmed by increased oleate accumulation in hepatocytes overexpressing Parkin and decreased uptake in Parkin –/– mouse embryonic fibroblasts and patient cells harboring complex heterozygous ...
13
Lipoprotein binding preference of CD36 is altered by filipin treatment
... 5% fat-free milk (w/v) for 2 hours at room temperature or overnight at ...anti-human CD36 antibody FA6-152 (Immu- notech) or a polyclonal rabbit anti-caveolin antibody (Transduction Laboratories) was used ...
9
Endothelial cell CD36 optimizes tissue fatty acid uptake
... cell CD36, or both, is ...cell, CD36 deletion increased fasting plasma FAs and postprandial ...of CD36 reduced heart lipid droplet accumulation after fasting, but CM deletion did not affect heart ...
15
Effect of the ratios of acetate and β hydroxybutyrate on the expression of milk fat and protein related genes in bovine mammary epithelial cells
... milk fat (FASN, ACACA, CD36, SCD, FABP3, LPL, PPARG, and SPEBF1) and milk protein-related genes (CSN1S1, CSN3, mTOR, 4E-BP1, S6KB1, STAT5, JAK2, and LEPTIN) were significantly affected by the addition of ...
11
Enhanced susceptibility of cyclin kinase inhibitor p21 knockout mice to high fat diet induced atherosclerosis
... 5'-CACGTGCTGCTCCACTTTTA-3'; CD36; sense: 5'-AGATGCA GCCTCATTTCCAC-3'; antisense: 5'-GCCTT- GGATGGAAGAACAAA-3'; HO-1; sense: 5'-TCCGAT- GGGTCCTTACACTC-3'; antisense: 5'- ATTGCCTGGATGTGCTTT TC-3' and β-actin; sense: ...
12
Platelet CD36 mediates interactions with endothelial cell–derived microparticles and contributes to thrombosis in mice
... ECs, CD36 mediates an antiangiogenic, proapoptotic response to thrombospondin-1 and -2 (9, 10), while on fat and muscle cells, it functions to facilitate transport of long-chain fatty acids for storage or ...
11
The role of CD36 receptor in the pathogenesis of atherosclerosis
... that CD36 participates in the inflammatory process by regulating membrane calcium ...influx. CD36 takes part in the activation of membrane calcium channels in response to endoplasmic reticulum ...a ...
6
Molecular Basis of Human CD36 Gene Mutations
... performance. CD36 acts as a major myocardial-specific LCFA transporter in humans ...the CD36 gene modulate lipid metabolism and car- diovascular risk in whites ...the CD36 gene in humans result in ...
9
Evaluation of the relationship between MARCO and CD36 single nucleotide polymorphisms and susceptibility to pulmonary tuberculosis in a Chinese Han population
... the CD36 gene are associ- ated with resistance to PTB. The CD36 gene is located on ...the CD36 gene may affect its expression and the function of the ...that CD36 −/− mice suffered fewer ...
9
Hydroxypropyl-Beta-Cyclodextrin Reduces Inflammatory Signaling from Monocytes: Possible Implications for Suppression of HIV Chronic Immune Activation
... The impaired ability of HP-BCD-treated monocytes to respond to LPS resulted from transcriptional regulation of IL-10 and TNF- ␣ . LPS-induced upregulation of TNF- ␣ and IL-10 mRNA in PBMCs was shown to be dependent on ...
13
Histidine rich glycoprotein inhibits the antiangiogenic effect of thrombospondin 1
... Angiogenesis is critical for the growth and proliferation of tumors as well as for normal develop- ment. We now describe a novel role for histidine-rich glycoprotein (HRGP) in the modulation of angiogenesis. HRGP is a ...
9
CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3β/β-catenin pathway
... of CD36 in GC metastasis, we measured CD36 expression in GC tissues by IHC, and an- alyzed the relationship between the level of CD36 in GC tissues and patients’ clinico-pathological characteristics ...
15