fatty acid binding protein 4
Fatty Acid Binding Protein 4 Silencing Attenuates Atherosclerosis Progression by Affecting Macrophage Apoptosis and Autophagy
... death. Fatty Acid Binding Protein 4 (FABP4) is an adipokine released by macrophages and is involved in multiple disease conditions including ...FABP4 protein could be a novel ...
11
Reduced airway levels of fatty-acid binding protein 4 in COPD: relationship with airway infection and disease severity
... Alveolar macrophages (Mɸ) are a central component of the innate immune response against airway infection. Several alterations of Mɸ in marker expression and func- tions have been previously described in COPD [7, 8]. ...
8
Fatty acid binding protein 4 in circulating leucocytes reflects atherosclerotic lesion progression in Apoe(-/-) mice
... identified fatty acid binding protein 4 (FABP4) mRNA to be augmented in mice with established dis- ease compared with young Apoe / or ...on protein level showed augmented FABP4 ...
8
The adipokine fatty-acid binding protein 4 and cardiac remodeling
... Furthermore, we observed the potential beneficial correlation between FABP4 and LVMI only in patients with lower FABP4 levels but the potential harmful correlation between FABP4 and N[r] ...
10
SERUM LEVELS OF ADIPOCYTE FATTY ACID BINDING PROTEIN 4 AND RETINOL BINDING PROTEIN 4 AS BIOMARKERS FOR EARLY DETECTION OF DIABETIC NEPHROPATHY IN TYPE 2 DIABETES
... This assay employs the quantitative sandwich enzyme immunoassay technique .A monoclonal antibody specific to RBP4 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any RBP4 ...
12
Fatty acid-binding protein 4 impairs the insulin-dependent nitric oxide pathway in vascular endothelial cells
... adhesion protein 1 (VCAM1), E- selectin and leukocyte adhesion to endothelial cells (data not shown), suggesting a more global effect of FABP4 on endothelial ...
8
Adipocytes promote cholangiocarcinoma metastasis through fatty acid binding protein 4
... catalytic binding proteins to perform the biological func- tions mentioned above ...of fatty acid binding protein family might be involved in this ...unesterified fatty ...
15
Identification of the association between FABP4 gene polymorphisms and milk production traits in Sfakia sheep
... the fatty acid binding protein 4 gene (FABP4) on milk production traits in Greek Sfakia ...content, protein content, lactose content, non-fat solid content, pH, and somatic cell ...
10
The FABP4 gene polymorphism is associated with meat tenderness in three Chinese native sheep breeds
... ABSTRACT: The aim of this study was to assess the association of single nucleotide polymorphisms (SNP) of sheep fatty acid binding protein 4 (FABP4) gene with longissimus thoracis ...
6
1 Computational Tools in the Discovery of FABP4
... inhibitors of fatty acid binding protein 4 using molecular docking screening. Floresta, G.; Apirakkan, O.; Rescifina, A.; Abbate, V., Discovery of High-Affinity Cannabinoid R[r] ...
12
Modulation of Fatty Acid Oxidation and Glucose Uptake by Oxytocin in Adipocytes
... Oxytocin (OT) is a hypothalamic neuropeptide synthesized and secreted by OT neurons. In addition to its conventional role in reproductive physiology, central OT also regulates various social behaviors, such as care, ...
14
Weight loss-induced changes in adipose tissue proteins associated with fatty acid and glucose metabolism correlate with adaptations in energy expenditure
... and fatty acid metabolism will give further insight in the underlying metabolic ...and fatty acid metabolism were measured in adipose tissue before and after an 8-wk very low en- ergy ...such ...
8
Exploring and Expanding the Fatty Acid Binding Protein superfamily in Fasciola species.
... FABP isoforms IV and V were expressed as recombinant forms in order to further understand the immune responses directed to the FABP family for diagnostic or vaccine potential. Despite its absence from F. hepatica ...
48
Association of peroxisome proliferated activated receptor (ppar) and fatty acid binding protein (fabp2) gene polymorphisms on t2dm and insulin resistance on different populations
... Insulin resistance and T2DM is mainly a genetic condition and initiates from the interactions of various genes and environmental factors. Figure 4 summarizes the main aspects that contribute to the progression of ...
14
Review: Omega-3 fatty acids transport through the placenta
... proteins, fatty acid transport proteins (FATPs, also known as SLC27A) are familiar for its cellular uptake of LC-PUFAs (Kazantzis and Stahl, ...at protein level of both the MVM and the BM (Campbell ...
8
The human fatty acid-binding protein family: Evolutionary divergences and functions
... C/EBP binding site, and it was found that this mutation exhibited sig- nificantly reduced competitive-binding capacity (50 per cent) for C/EBPa compared with the wild-type (WT) FABP4 ...
22
Heart fatty acid binding protein and Aβ-associated Alzheimer’s neurodegeneration
... ε 4 allele of apolipopro- tein E (APOE ε 4), diagnostic status (AD vs mild cognitive impairment (MCI) vs healthy elderly controls (HC)), and disease severity (CDR-Sum of Boxes score at baseline) to examine ...
9
Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome
... intestinal fatty acid binding protein (I-FABP), a marker associated with enterocyte damage, were assayed using an ELISA (Hycult Biotechnology, Uden, the Netherlands) ac- cording to the ...
12
Fatty acid binding protein Role in esterification of absorbed long chain fatty acid in rat intestine
... oleate binding to FABP:flavaspidic acid-N-methyl-glucaminate and ...after 4 min. The inhibition by flavaspidic acid was reversible with higher oleate ...flavaspidic acid nor ...
11
Sex Differences in Long Chain Fatty Acid Utilization and Fatty Acid Binding Protein Concentration in Rat Liver
... incorporated significantly more 14 C into glycerolipids, especially triglycerides, and into oxidation products than did male cells, per milligram cell protein. At 0.44 mM oleate, incorporation into triglycerides ...
11