Fe/sub 3/C nanoparticles
Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... Dex/Fe 3 O 4 using the EDC–NHS crosslinking ...grafted nanoparticles were also able to adhere to ...Bis/Dex/Fe 3 O 4 on the bone surface and thermalize by the RF ...onto Fe ...
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Effects of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> combinated with gambogic acid on apoptosis of SMMC-7721 cells
... After drug treatment, total protein was isolated from the SMMC-7721 cells (Whole Cell Lysis Assay, KGP250; KeyGen Biotech Co., Ltd.) and measured using BCA protein quantitation assay kit (KGPBCA; KeyGen Biotech Co., ...
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Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... the Fe 3 O 4 nanoparticles were biocompatible and suitable for biomedi- cal ...The Fe 3 O 4 was treated with low temperature intermittent sterilization, and RPMI 1640 culture medium ...
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Effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and wogonin on the reversal of multidrug resistance in K562/A02 cell line
... After treatment as before, total protein was isolated on ice and subjected to 10% sodium dodecyl sulfate polyacrylamide gel electrophoresis using a modified radioimmunoprecipitation assay buffer, and then transferred to ...
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Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... and the blots were stained with specific primary antibodies, including anti-bcl-2, anti-bax, anti-survivin, anti-bcl-rambo, anti-active caspase-3, and anti-GAPDH antibodies overnight at 4 ° C. Then, the ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... Forty-two mice were randomly assigned to either the non- exercised control group (n = 6) or exercise groups (n = 36). Thirty-six mice were placed into plastic cylinders (23 cm tall × 14 cm diameter) containing water ...
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The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... group) Fe 3 O 4 -MNPs, were dissolved in normal saline and intravenously (iv) injected into mice ...° C to separate plasma and blood ...° C for determination of ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... molecular weights. Immunoblots for expression of p38, p-p38, JNK, p-JNK, HO-1, ERK, c-Jun, cleaved caspase 3, Bcl2, Bax, P50, p53, Nrf2, Akt, and GAPDH were detected. All antibodies for Western blot in this ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... (FeCl 3 ⋅ 6H 2 O), ferrous chloride tetrahydrate (FeCl 2 ⋅ 4H 2 O), and ammonium hydroxide (25 wt%) were purchased from Fluka (Buchs, ...° C for 12 hours and used without further ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... Cells were lysed in Radioimmunoprecipitation assay buffer (Sigma-Aldrich) containing protease inhibitors (Sigma- Aldrich). Total protein concentration was determined by Bio- Rad protein assay reagent (Bio-Rad ...
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Co-encapsulation of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and doxorubicin into biodegradable PLGA nanocarriers for intratumoral drug delivery
... these were cultured at 37 ° C for 24 hours in an atmosphere containing 5% carbon dioxide. DOX-MNPs or free DOX were diluted with culture medium to 5 µ g/mL, followed by coculture with aforementioned cell lines for ...
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The reversal effect of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles loaded with cisplatin on SKOV3/DDP ovarian carcinoma cells
... The MDR human ovarian cancer cell line, SKOV3/DDP, was obtained from the Chinese Academy of Medical Sciences and Peking Union Medical College. The SKOV3/DDP cell line was cultured in a flask in RPMI-1640 containing 10% ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... with Fe 3 O 4 -MNP increased to 41.71 ° C ± 1.52 ° C and in those treated with Fe 3 O 4 -MNP- DNR-5-BrTet the temperature increased to ...° C ± 1.8 ° C after 20 ...
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Prevention of acute graft-versus-host disease by magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> combined with cyclosporin A in murine models
... Methods: BALB/c mice preconditioned with total-body irradiation generated aGVHD and then were followed with allo-HSCT from allogeneic C57BL/6. Recipient mice were randomly divided into five groups and then given ...
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Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... ° C, and then diluted as needed in RPMI 1640 medium (Gibco/BRL, Carlsbad, ...MNPs-Fe 3 O 4 (State Key Lab of Bioelectronics, Nanjing, China) were well distributed in RPMI 1640 medium containing 10% ...
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Study of the intra-arterial distribution of Fe<sub>3</sub>O<sub>4</sub> nanoparticles in a model of colorectal neoplasm induced in rat liver by MRI and spectrometry
... Figure 3 Scatter plot of the iron concentration values quantified using ICP-MS against the SI ratio from healthy liver and tumor tissues, calculated from DP* and T2*-weighted ...
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Ultrasmall superparamagnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles: honey-based green and facile synthesis and in vitro viability assay
... of Fe 3 O 4 -NPs, different amounts of natural honey ...FeCl 3 ⋅ 6H 2 O and FeCl 2 ⋅ 4H 2 O (with a 2:1 molar ratio) were added under continuous stirring and nitrogen gas bubbling to inhibit ...The ...
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Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>/DNR magnetic nanoparticles in the treatment of hematologic malignancies
... The Fe 3 O 4 -MNPs/DNR were scrubbed with distilled water twice, lixiviated with saline, with a final concentration reached of 100 ...° C, the process of hemolysis was observed macroscopically, the ...
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Inhibition of choriocarcinoma by Fe<sub>3</sub>O<sub>4</sub>-dextran-anti-ß-human chorionic gonadotropin nanoparticles containing antisense oligodeoxynucleotide of heparanase
... FeCl 3 ⋅ 6H 2 O, FeCl 2 ⋅ 4H 2 O, and other chemicals were from local suppliers and were of analytical ...° C. Mixtures of Fe 3 O 4 -dextran-anti- β HCG-Hpa ASODN or NSODN Fe 3 O ...
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Magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells
... MNP-Fe 3 O 4 , adriamycin + MNP-Fe 3 O 4 , daunorubicin + MNP-Fe 3 O 4 , dexamethasone + MNP-Fe 3 O 4 , and RPMI 1640 alone were added to these cells and cultured ...
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