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FGF-21

Perspective of FGF-21, a new metabolic regulator in neurocontrol of circulation and pathological process of hypertension

Perspective of FGF-21, a new metabolic regulator in neurocontrol of circulation and pathological process of hypertension

... of FGF-21 is dramatically increased; therefore, the FGF-21 is also termed as the hunger ...of FGF-21 is controlled by the peroxisome proliferator-activated receptors (PPARα) and ...

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Raised FGF 21 and Triglycerides Accompany Increased Energy Intake Driven by Protein Leverage in Lean, Healthy Individuals: A Randomised Trial

Raised FGF 21 and Triglycerides Accompany Increased Energy Intake Driven by Protein Leverage in Lean, Healthy Individuals: A Randomised Trial

... = 21, 5% missing) and diastolic (n = 21, 5% missing) blood pressure, fasting glucose (n = 18, 18% missing), FGF-21 (n = 11, 50% missing), triglycer- ides (n = 19, 14% missing), total ...

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Acute Sprint Interval Exercise Induces a Greater FGF-21 Response in Comparison to Work-Matched Continuous Exercise

Acute Sprint Interval Exercise Induces a Greater FGF-21 Response in Comparison to Work-Matched Continuous Exercise

... and FGF-21 analyses, but additional steps for sample preparation should be taken including: 1) pre- chilling EDTA tubes with ice baths before taking blood samples and 2) consistent freezer storage at ...

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FGF 21 as a novel metabolic regulator

FGF 21 as a novel metabolic regulator

... In vivo protocols. The protocols used in these studies were approved by the Eli Lilly Research Laboratories Institutional Animal Care and Use Commit- tee. Mice were maintained in a controlled environment (21 ± ...

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Original Article Fibroblast growth factor-21 is positively associated with atrial fibrosis in atrial fibrillation patients with rheumatic heart disease

Original Article Fibroblast growth factor-21 is positively associated with atrial fibrosis in atrial fibrillation patients with rheumatic heart disease

... that FGF-21 can im- prove the endothelial function in early stage of atherosclerosis, and prevent the development of coronary heart disease ...that FGF-21 increased in plasma of patients with ...

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BACE-1, PS-1 and sAPPβ Levels Are Increased in Plasma from Sporadic Inclusion Body Myositis Patients: Surrogate Biomarkers among Inflammatory Myopathies

BACE-1, PS-1 and sAPPβ Levels Are Increased in Plasma from Sporadic Inclusion Body Myositis Patients: Surrogate Biomarkers among Inflammatory Myopathies

... from 21 sIBM patients and 20 age- and gender-paired healthy controls were collected and stored at ...and FGF-21 levels and decreased content in CoQ), only amyloidogenic degenerative markers including ...

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Original Article Elevated serum levels of fibroblast growth factor 21 from patients with nephrolithiasis

Original Article Elevated serum levels of fibroblast growth factor 21 from patients with nephrolithiasis

... serum FGF-21 proportions were related to carotid atherosclerosis among human beings, and independent from the previous danger ele- ments such as adverse lipid profiles and ...study, FGF-21 ...

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Sex-specific association between fibroblast growth factor 21 and type 2 diabetes: a nested case-control study in Singapore Chinese men and women

Sex-specific association between fibroblast growth factor 21 and type 2 diabetes: a nested case-control study in Singapore Chinese men and women

... of FGF-21 levels among control participants, and the lowest quartile served as the refer- ence ...between FGF-21 and ...since FGF-21 levels were associated with hs-CRP levels ...

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Elevated serum fibroblast growth factor 21 levels correlate with immune recovery but not mitochondrial dysfunction in HIV infection

Elevated serum fibroblast growth factor 21 levels correlate with immune recovery but not mitochondrial dysfunction in HIV infection

... serum FGF-21 levels do not appear to be a sensitive or specific marker of muscle mito- chondrial dysfunction in contemporary anti-retroviral treated ...serum FGF-21 levels in the ...

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Hepatic, adipocyte, enteric and pancreatic hormones: response to dietary macronutrient composition and relationship with metabolism

Hepatic, adipocyte, enteric and pancreatic hormones: response to dietary macronutrient composition and relationship with metabolism

... that FGF-21 levels de- creased in response to dietary intervention with marked ef- fect by macronutrient ...of FGF-21 in our study are lower than some published reports [26], yet consistent ...

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Serum Fibroblast Growth Factor 21 as a Novel Biomarker in Prediction of Coronary Artery Disease Severity

Serum Fibroblast Growth Factor 21 as a Novel Biomarker in Prediction of Coronary Artery Disease Severity

... FGF-21 has been proposed as a potential therapeutic target for type 2 diabetes in humans as it inhibits hepatic glycogen degradation, thus reducing levels of circulating glucagon. FGF21- mediated effects ...

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THE STERATEGIC ROLE OF FIBROBLAST GROWTH FACTOR-21IN OBESITY

THE STERATEGIC ROLE OF FIBROBLAST GROWTH FACTOR-21IN OBESITY

... However, recently FGF21 is considered as a novel regulator of oxidative stress. The oxidative stress is associated with the metabolic disorders, including obesity; type 2 diabetes and insulin resis- tance (Cao & ...

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Hepatocellular carcinoma and non-alcoholic steatohepatitis: the state of play

Hepatocellular carcinoma and non-alcoholic steatohepatitis: the state of play

... A Chinese group found that the serum levels of cytokeratin-18 M30 fragment Ck-18-M30; a marker of hepatocyte apoptosis fibroblast-21 FGF-21; related to decreasing blood glucose, lipid an[r] ...

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The role of glucagon on type 2 diabetes at a glance

The role of glucagon on type 2 diabetes at a glance

... factor 21 (FGF-21) and GLP-1 exhibited by these ...of FGF-21 (with a FGF-21 antibody) and GLP-1 (with its antagonist Exendin 9–39) actions resulted in hyperglycemia in ...

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Effect of Vigorous Aerobic Exercise on Serum Levels of SIRT1, FGF21 and Fetuin A in Women with Type II Diabetes

Effect of Vigorous Aerobic Exercise on Serum Levels of SIRT1, FGF21 and Fetuin A in Women with Type II Diabetes

... Before the intervention, there was no significant difference between the control and the exercise groups. The eight weeks of high- intensity aerobic exercise caused a significant decrease in body weight, BMI, A1C level, ...

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FGF/MAPK signaling is required in the gastrula epiblast for avian neural crest induction

FGF/MAPK signaling is required in the gastrula epiblast for avian neural crest induction

... for FGF signaling within the epiblast from pre-gastrula stages (Streit et ...that FGF, via the Erk signaling cascade, acts on the medial epiblast from the blastula through to the gastrula stage to specify ...

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FGF receptor signalling controls neural cell diversity in the zebrafish hindbrain by regulating olig2 and sox9

FGF receptor signalling controls neural cell diversity in the zebrafish hindbrain by regulating olig2 and sox9

... in FGF-receptor signalling, we exploited the stability of the Kaede protein in the Tg(erm:gv)(uas:k) ...that FGF-receptor signalling in rhombomere centre progenitors controls olig2 expression and ...

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Shisa2 promotes the maturation of somitic precursors and transition to
the segmental fate in Xenopus embryos

Shisa2 promotes the maturation of somitic precursors and transition to the segmental fate in Xenopus embryos

... Fig. 4. Shisa2 controls the position of the wavefront. (A,A ) MO targeting Shisa2 mRNA. (A) Sequences of Shisa2MO1 and MO2. (A ) MO3 was designed to block mRNA splicing. Immature and mature Shisa2 mRNA was detected by ...

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FGF 2 controls the differentiation 
of resident cardiac precursors 
into functional cardiomyocytes

FGF 2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes

... others, FGF-2 has been implicated in cell proliferation, survival, and differentiation (16, ...heart, FGF-2 expression was shown to be upregulated after cardiac injury, such as ischemia/reperfusion, or in ...

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