fitness effects
The Distribution of Fitness Effects Among Beneficial Mutations
... of fitness effects among beneficial mutations regardless of the underlying distri- bution of allelic ...of fitness effects among beneficial mutations is ap- proximately invariant over a wide ...
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New methods for inferring the distribution of fitness effects for INDELs and SNPs
... Small insertions and deletions (INDELs; ≤50bp) are the most common type of variability after SNPs. However, compared to SNPs, we know little about the distribution of fitness effects (DFE) of new INDEL ...
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Distributions of Beneficial Fitness Effects in RNA
... beneficial fitness Figure ...ben- effects of wild-type alleles from random ...eficial fitness effects of wild-type alleles from the high-fitness 5721 adaptive walks starting from random ...
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The Evolutionarily Stable Distribution of Fitness Effects
... Figure 3 The equilibrium DFE and steady-state substitution rate. (A) The equilibrium ratio of the beneficial mutation rate to the deleterious muta- tion rate for mutations with absolute effect j s j ; averaged over 100 ...
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Modes of Reproduction and the Accumulation of Deleterious Mutations With Multiplicative Fitness Effects
... similar effects as found that takes place after which diploidy is ...when fitness effects of deleterious alleles are multi- the same and identical to the procedure in a ...
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Additive Phenotypes Underlie Epistasis of Fitness Effects
... genotypic effects are additive with regard to phenotype, and epistatic effects on fitness arise from a nonlinear phenotype–fitness map resulting from an intermediate phenotypic ...fitness effects ...
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Fitness effects of Ty transposition in Saccharomyces cerevisiae.
... clones is defined as a closely related group of clones defined by the Tyl hybridization spectra (see MATE- RIALS AND METHODS for further details).. Sample sizes for each [r] ...
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A Method for Inferring the Rate of Occurrence and Fitness Effects of Advantageous Mutations
... doubtful whether the information would be sufficient to estimate parameters of a distribution in practice. We have fitted a gamma distribution of negatively selected muta- tional effects. Although this distribution ...
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A Comparison of Models to Infer the Distribution of Fitness Effects of New Mutations
... numbers of alleles sequenced will increase their perfor- mance. These models can also help in determining whether the DFE has multiple modes. We note that we have exam- ined only one particular case of each type of ...
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Is there selection on RFLP differences in mitochondrial DNA?
... A population model was constructed using the known fitness effects of the incompatibility system, with the result that the population trajectories can be completely explain[r] ...
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Properties of Ethylmethane Sulfonate-Induced Mutations Affecting Life-History Traits in Caenorhabditis elegans and Inferences About Bivariate Distributions of Mutation Effects
... pleiotropic effects ation among individuals and the basis for evolu- on two or more traits, the overall effect of that mutation tionary ...on fitness may be underestimated if only one of the distribution of ...
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Mendel's Accountant: a biologically realistic forward-time population genetics program
... the fitness effect function needs to be computed from the stored mutation index m, Mendel allocates an array to contain the cumulative heterozygous fitness effects from all the mutations associated ...
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The effects of low-impact mutations in digital organisms
... mutational fitness effects, merit bonuses were modified in the ...file. Fitness effects of 0, ...of fitness. Uniform effects were used, such that all advantageous operations ...
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Estimation of Deleterious Genomic Mutation Parameters in Natural Populations by Accounting for Variable Mutation Effects Across Loci
... constant fitness effects of DGM and hence is biased under variable fitness effects of ...mutation effects across loci. Under variable mutation effects, the mean fitness ...
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The effects of four weeks of creatine supplementation and high-intensity interval training on cardiorespiratory fitness: a randomized controlled trial
... Training began at least 24-48 hours following the TTE test. Participants were required to visit the lab five days per week, for six weeks, to perform the HIIT. A two-week familiarization training period was implemented ...
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The Relationship between Aerobic Fitness and Concussion Risk, Severity, and Recovery in High School Football
... The purpose of this study was to examine the effects of aerobic fitness level on concussion risk, severity and recovery in high school football players.. Participants.[r] ...
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The Effect of Vestibular Training on the Quality of Life and Components of Physical Fitness in the Inactive Elderly
... physical fitness, followed by inertia and increased risk of acute and chronic diseases, reduces the performative ability of individuals and their senses and perceptions ...
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New directions in obesity management: the effects of fitness literacy program on cardiovascular fitness and social physical and appearance anxiety among inactive obese women
... Fifty obese women enrolled in this study were selected based on the following criteria sampling principles: samples of the current study 50 inactive obese women were randomly assigned. Inclusion criteria: (a) age 30-40 ...
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Effects of intra gene fitness interactions on the benefit of sexual recombination
... follow fitness gradients in two different spaces: in nucleotide sequence space, and allele sequence space, ...for fitness at these two scales, between nucleotides and between genes, may be qualitatively ...
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Physical Education Method: Effects on Physical Fitness and Competency of the Students
... the effects of traditional method (current methods in Iranian schools) with sport education on physical fitness and ...the effects of two methods of sport education and traditional ...physical ...
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