Fluconazole-resistant
Fluconazole Prophylaxis in Extremely Low Birth Weight Neonates Reduces Invasive Candidiasis Mortality Rates Without Emergence of Fluconazole-Resistant Candida Species
... involving fluconazole- resistant Candida species was assessed retrospectively by examining the Candida species distribution over a 6-year period (2000-2001, before FP, and 2002-2006, after FP) and by ...
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In vitro antifungal activity of essential oils from local plants against fluconazole-resistant oral Candida albicans isolates
... The results of disc diffusion method for testing the antifungal activity of both Rosemary and Thyme EOs are summarized in Figure 1. It was found that both EOs are active against the selected fluconazole ...
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Antifungal activity of essential oils against Fluconazole resistant fungi
... Essential oils (also called volatile oils) are natural, complex, aromatic, oily liquids obtained from plant materials (flowers, buds, seeds, leaves, twigs, bark, herbs, wood, fruits, and roots) and composed mainly of ...
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Evaluation of Antifungal efficacy of Plumbago sp. against clinically isolated fluconazole resistant Candida albicans
... The results of the present study clearly indicated that ethanolic extract of Plumbago zeylanica can be effectively utilized for control of Fluconazole resistant Candida albicans. However, further research ...
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Frequency of Decreased Susceptibility and Resistance to Echinocandins among Fluconazole Resistant Bloodstream Isolates of Candida glabrata
... for resistant organisms (4, 5, 11, 18, 24, 33–35, 48, 56, 57, ...among fluconazole-resistant strains of ...or resistant [R]) to one or more of the echinocandins were further examined for ...
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Original Article Drug interaction of traditional Chinese medicines with fluconazole against fluconazole resistant strains of Candida albicans
... against fluconazole resistant strains of Candida ...with fluconazole is also ...with fluconazole, MIC was sig- nificantly decreased ranging from 2 to 32 μg/ ...with fluconazole, ...
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Effect of biogenic selenium nanoparticles on ERG11 and CDR1 gene expression in both fluconazole-resistant and -susceptible Candida albicans isolates
... The expression of ERG11 and CDR genes have been identified as the mechanisms responsible for resistance to azole in Candida species. Regarding this and given the alterations in the structure of these two genes, the ...
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Correlation between In Vitro and In Vivo Antifungal Activities in Experimental Fluconazole Resistant Oropharyngeal and Esophageal Candidiasis
... to fluconazole and in vivo response in a rabbit model of fluconazole-resistant ...of fluconazole were determined by NCCLS methods. Three fluconazole-susceptible (FS) (MIC, < ...three ...
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Outbreak of candidemia caused by fluconazole resistant Candida parapsilosis strains in an intensive care unit
... During July-2011 and February-2012, we observed a dramatic increase in the incidence of candidemia re- ported in ICU patients from a single institution com- pared to the previous period between January-2006 and ...
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Quantitation of ergosterol content and gene expression profile of ERG11 gene in fluconazole-resistant Candida albicans
... he incidence of resistance to Candida treatment has surged during the recent decades. Emergence of fluconazole-resistant Candida species has been progressively reported in the last 30 years [1]. Several ...
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Emergence of fluconazole resistant strains of Candida albicans in patients with recurrent oropharyngeal candidosis and human immunodeficiency virus infection
... After repeated use of fluconazole for therapy of oropharyngeal candidosis, the emergence of in vitro fluconazole-resistant Candida albicans isolates MIC, 2 25 ,ig/ml together with oral c[r] ...
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Quantification of CDR1 Gene Expression in Fluconazole Resistant Candida Glabrata Strains Using Real-time PCR
... Although fluconazole is the most effective antifungal agent against candidiasis, ...glabrata, fluconazole-resistant strains have been increased recently overexpression or mutations of ATP-binding ...
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IN VITRO SENSITIVITY OF AMPHOTERICIN B, ITRACONAZOLE AND FLUCONAZOLE – RESISTANT AGAINST CANDIDA ALBICANS
... of Fluconazole and azole agents, lessons in vitro have displayed synergy against Candida species, variable from 38 to 100% of isolates, depending on the grouping and crossing point definitions 28, 29, 30 ...
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Evolution of Fluconazole Resistant Candida albicans Strains by Drug Induced Mating Competence and Parasexual Recombination
... Although C. albicans primarily propagates in a clonal fashion, its capacity to mate suggests that a parasexual cycle is used by this fungus to generate diversity (48–50). Mating between unrelated strains, which would ...
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Detection of ERG11 point mutations in iranian fluconazole-resistant Candida albicans isolates
... Background and Purpose: Candidiasis is referred to a group of superficial and deep-tissue fungal infections often caused by Candida albicans. The superficial infections affect the oral, oropharynx, esophagus, and vaginal ...
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Simple method for detecting fluconazole resistant yeasts with chromogenic agar
... with fluconazole MICs determined by NCCLS broth macrodilution (9) were tested blindly on both RPMI 1640 with fluconazole and CHROMagar Candida with ...(10). Fluconazole was added to the media to ...
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Over expression of efflux pumps genes in resistant Candida albicans clinical isolated from oral colonization in Iranian HIV positive patients
... Oral candidiasis is mainly treated with the use of Fluconazole. Treatment of oral candidiasis may be problematic due to either inherent resistance of candida species or acquired drug-resistance. Antifungal drugs ...
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"De-escalation" strategy using micafungin for the treatment of systemic <em>Candida</em> infections: budget impact in France and Germany
... of fluconazole treatment does not impact the overall efficacy of micafungin for the fluconazole-resistant ...that fluconazole-resistant patients who had inappropriate treat- ment for 3 ...
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Frequent detection of ‘azole’ resistant Candida species among late presenting AIDS patients in northwest Ethiopia
... azoles: Fluconazole: resistant ≥ 64 μg/ml, susceptible-dose dependent (S-DD) 16-32 μg/ml and susceptible ≤ 8 μg/ml; itraconazole: re- sistant ≥ 1 μg/ml, SDD ...ketoconazole: resistant ≥ 4 ...and ...
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Clonal and Spontaneous Origins of Fluconazole Resistance in Candida albicans
... pathway. Fluconazole is currently the most widely used antifungal drug because it can be given orally, lacks major side effects, and has broad efficacy against most patho- genic yeasts, including ...However, ...
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