Fluid-induced shear stress
Fluid-induced, shear stress-regulated extracellular matrix and matrix metalloproteinase genes expression on human annulus fibrosus cells
... as fluid- induced shear stress from the ...maximum shear stress in our chip was calculated to be 1 dyne/cm 2 when the flow rate was set to ...
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Oscillatory fluid flow influences primary cilia and microtubule mechanics
... fluid flow induced shear stress on the microtubule based primary cilium and cytoplasmic 2.. microtubule network in kidney and bone cells.[r] ...
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Fluid shear stress-induced TGF-beta/ALK5 signaling in renal epithelial cells is modulated by MEK1/2
... of shear stress-treated ...upon fluid flow. In addition, increased flow-induced api- cal endocytosis might play a role, as recently published for PTECs ...
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Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts
... to fluid flow showed a primary cilium dependent extracellular Ca 2⫹ - dependent intracellular Ca 2 ⫹ release ...flow- induced Ca 2⫹ flux was shown to be independent of primary cilia (10), and inhibition of ...
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Shear stress–induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure
... in fluid shear stress–induced cellular effects in isolated endothelial cells with suppressed adrenomedullin and adrenomedullin receptor expres- sion as well as in flow-induced ...
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Mathematically modeling fluid flow and fluid shear stress in the canaliculi of a loaded osteon
... FSS induced in the ...canalicular fluid flow behavior (see Fig. 5). Although the actual fluid flow rates have not been measured in vivo, in vivo bone strains have been directly meas- ured in humans ...
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P2Y2 and Gq/G11 control blood pressure by mediating endothelial mechanotransduction
... to fluid shear stress exerted by the flowing ...in fluid shear stress–induced endothelial effects, but how fluid shear stress initiates the response ...
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Mechanically induced osteogenic lineage commitment of stem cells
... including fluid shear stress in MC3T3-E1 osteoblast- and MLO-Y4 osteocyte- like cells ...[63]. Fluid flow-induced paracrine signaling in bone may also be primary cilia ...to ...
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Real-time vascular mechanosensation through ex vivo artery perfusion
... to fluid flow. The calcium response profile for induced fluid flow in wild type mouse tissue (Figure 4) is very similar to the extensively characterized profile of endothelial in vitro responses ...
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Fluid Shear Stress Promotes Autophagy in Hepatocellular Carcinoma Cells
... There are a lot of works highlight the direct involvement of autophagy in cell migration and cancer metastasis [5, 12]. The autophagy regulated tumor cell motility by various mechanisms such as synergistic interaction ...
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Endothelial fluid shear stress sensing in vascular health and disease
... Upstream of these events, many mechanotransducers have been proposed, including PECAM-1, the apical glycocalyx, ion channels, G proteins, protein kinases, and primary cilia (26–29). However, a coherent model of flow ...
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Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress induced platelet aggregation
... A fluid shear stress of 180 dyn/cm2 was applied for 0.5 and 5 min to platelets in citrated plasma or blood in a cone and plate viscometer with minimal platelet-surface interactions. Platelets ...
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Parametric Investigations of the Induced Shear Stress by a Laser-Generated Bubble
... Of Fluid (VOF) ...the induced shear stress and pressure pulse in the vicinity of the wall, for a variety of bubble sizes and bubble wall ...size, induced pressure field and shear ...
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Energetic Balance for the Flow Induced by a Constantly Accelerating Plate in a Second Grade Fluid
... the shear stress at the wall and the boundary layer thickness corresponding to the unsteady flow of a second grade fluid, due to a constantly accelerating plate, are established in exact and ap- ...
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Original Article β-catenin in VSMC proliferation induced by fluid shear stress through the non-Wnt signaling pathway
... between fluid shear stress (FSS), vascular smooth muscle cells (VSMCs) proliferation during atherosclerosis (AS), and ...low shear stress is ...AS induced by ...
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A thin rivulet of perfectly wetting fluid subject to a longitudinal surface shear stress
... One context in which these ideas may have practical application is the intriguing problem of the so-called Rain-Wind Induced Vibrations (RWIVs) of the cables of cable-stayed bridges such as the Erasmus Bridge in ...
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Behaviour of Normal Strength concrete and High Strength concrete subjected to In-plane Shear
... the shear transfer in uncracked fibrous concrete using push off and modified push off ...crossing shear plane, and the ratio of direct shear stress to shear ...the shear plane ...
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Computer aided fatigue design
... The three areas of computer aided engineering mentioned previously are well established as separate entities. At t h e p r e s e n t t i m e c o m m e r c i a l l y a v a i l a b l e l i n k s a r e established between ...
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Two-Fluid Mathematical Models for Blood Flow in Stenosed Arteries: A Comparative Study
... The objective of the present analysis is to compare and bring out the advantages of the two- fluid Casson model over the two-fluid Herschel-Bulkley model. It is observed that the typical value of the power ...
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PubMedCentral-PMC5052530.pdf
... Higher frequency enhanced gene expression induced by both horizontal and vertical LIV. Gene arrays using the most effective signal combinations at 30 Hz (30 Hz-1 g) and 100 Hz (100 Hz-0.15 g) showed that genes ...
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