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Fluid shear stress

Endothelial fluid shear stress sensing in vascular health and disease

Endothelial fluid shear stress sensing in vascular health and disease

... the frictional force from blood flow (fluid shear stress [FSS]) that is parallel to the vessel wall, and the force from blood pressure that stretches the vessel wall. These forces are sensed and ...

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FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

... as fluid shear stress, govern multiple aspects of endothelial cell ...abnormal shear stress sensing, promoting junction disassembly and entry into the cell ...oscillatory shear ...

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Fluid Shear Stress Promotes Autophagy in Hepatocellular Carcinoma Cells

Fluid Shear Stress Promotes Autophagy in Hepatocellular Carcinoma Cells

... The autophagy in cancer cells is recognized as an essential hallmark of tumors, which can enhance cancer cell migration and invasion, and result in high incidence of tumor metastasis. The fluid shear ...

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Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia

Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia

... The late and focal appearance of HHT lesions is likely related to the need for a so-called second hit to inactivate the normal allele and/or other related pathways. Embryonic deletion of Acvrl1 or Eng in mice leads to ...

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NITRIC OXIDE PRODUCTION BY BONE CELLS IS FLUID SHEAR STRESS RATE DEPENDENT

NITRIC OXIDE PRODUCTION BY BONE CELLS IS FLUID SHEAR STRESS RATE DEPENDENT

... to fluid shear stress, in terms of NO production, is rapid and rate-dependent, might further the description and prediction of bone loss by existing theoretical models (42, ...

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Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells

Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells

... ABSTRACT Laryngeal squamous cell carcinoma (LSCC) is one of the most commonly diagnosed malignancies with high occurrence of tumor metastasis, which usually exposes to fluid shear stress (FSS) in ...

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Cellular fluid shear stress on implant surfaces—establishment of a novel experimental set up

Cellular fluid shear stress on implant surfaces—establishment of a novel experimental set up

... by fluid shear stress, which depends on exposure time and strength [22, ...actin stress fibres, which in turn align towards the longitu- dinal cell axis and mainly appear near the nucleus [8, ...

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Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts

Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts

... which fluid-flow induced shear stress is transduced and mod- ...external stress (28) and this reorganization has been shown to be dependent on the type, magni- tude, and duration of the ...

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A comparison of strain and fluid shear stress in stimulating bone cell responses   a computational and experimental study

A comparison of strain and fluid shear stress in stimulating bone cell responses a computational and experimental study

... or fluid flow through the canalicular network, are not well ...and fluid shear stress ...Pa fluid shear stress and 1,000 µε substrate strain stimulation because of ...

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Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin interacting protein in endothelial cells

Fluid shear stress inhibits vascular inflammation by decreasing thioredoxin interacting protein in endothelial cells

... physiologic fluid shear stress exerts atheroprotective effects in vivo, since atherosclerosis pref- erentially occurs in areas of disturbed flow or low shear stress, whereas regions ...

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Nuclear factor kappa B interacts functionally with the platelet derived growth factor B chain shear stress response element in vascular endothelial cells exposed to fluid shear stress

Nuclear factor kappa B interacts functionally with the platelet derived growth factor B chain shear stress response element in vascular endothelial cells exposed to fluid shear stress

... as fluid shear stress, that act on the endothelial lining of the cardiovascular system can modulate the expression of an expanding number of genes crucial for homeostasis and the pathogenesis of ...

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Fluid shear stress-induced TGF-beta/ALK5 signaling in renal epithelial cells is modulated by MEK1/2

Fluid shear stress-induced TGF-beta/ALK5 signaling in renal epithelial cells is modulated by MEK1/2

... Surprisingly, fluid flow-induced expression of most SMAD2/3 targets was further enhanced upon MEK ...that fluid shear stress induces auto- crine TGF-β/ALK5-induced target gene expression in ...

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Proteomic analysis of Staphylococcus aureus biofilm cells grown under physiologically relevant fluid shear stress conditions

Proteomic analysis of Staphylococcus aureus biofilm cells grown under physiologically relevant fluid shear stress conditions

... under fluid shear ...under fluid high shear, while the abundance of surface proteins, especially the fibronectin-binding and collagen binding surface pro- teins, remained ...high fluid ...

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Mathematically modeling fluid flow and fluid shear stress in the canaliculi of a loaded osteon

Mathematically modeling fluid flow and fluid shear stress in the canaliculi of a loaded osteon

... canalicular fluid flow behavior (see Fig. 5). Although the actual fluid flow rates have not been measured in vivo, in vivo bone strains have been directly meas- ured in humans (1200–1900 με [39]) during ...

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Original Article β-catenin in VSMC proliferation induced by fluid shear stress through the non-Wnt signaling pathway

Original Article β-catenin in VSMC proliferation induced by fluid shear stress through the non-Wnt signaling pathway

... plays a primary role in the early stage of AS, and hyperlipidemia promotes pathological development. Multiple other studies have converged on β-catenin activation as a key component of arteriosclerotic physiology. In ...

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Experimental Analysis of Wall Flow Pattern and Fluid Shear Stress Effects on Creeping Flow Field in Convergent-Divergent Microchannels

Experimental Analysis of Wall Flow Pattern and Fluid Shear Stress Effects on Creeping Flow Field in Convergent-Divergent Microchannels

... actually fluid transfer processes and suspension two-phase flows in the micro channels with micron dimensions and high aspect ...the fluid and scattered particles are pumped into the channel via micro pumps ...

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A thin rivulet of perfectly wetting fluid subject to a longitudinal surface shear stress

A thin rivulet of perfectly wetting fluid subject to a longitudinal surface shear stress

... surface shear stress τ ...The fluid is assumed to be Newtonian with constant density ρ, viscosity µ, and surface tension ...the fluid are governed by the familiar mass-conservation and ...

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RETRACTED ARTICLE: Velocity and shear stress for an Oldroyd-B fluid within two cylinders

RETRACTED ARTICLE: Velocity and shear stress for an Oldroyd-B fluid within two cylinders

... Abstract This paper aims to explore the possible solutions for the movement of an Oldroyd-B fluid placed under certain conditions, i.e. the fluid is present within two cylinders, which are coaxial and oscillating within. ...

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Exact solution for motion of an Oldroyd-B fluid over an infinite flat plate that applies an oscillating shear stress to the fluid

Exact solution for motion of an Oldroyd-B fluid over an infinite flat plate that applies an oscillating shear stress to the fluid

... the fluid is moving according to the steady-state ...the shear stress on the ...the shear. This is obvious, because at t = 0 the shear stress on the boundary is zero for sine ...

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Stem Cells Culture Bioreactor Fluid Flow, Shear Stress and Microcarriers Dispersion Analysis Using Computational Fluid Dynamics

Stem Cells Culture Bioreactor Fluid Flow, Shear Stress and Microcarriers Dispersion Analysis Using Computational Fluid Dynamics

... In real conditions, stem cells culture on the micro carriers and in Mobius CellReady 3L, is a 3 phase (Solid-Gas- Liquid) mixture. These bioreactors are equipped with air sparger which introduces the air bubbles as ...

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