FSHR gene
FSHR Gene Polymorphisms Causes Male Infertility
... two FSHR gene polymorphisms G919A (Ala307Thr) and A2039G (Asn680Ser) in Eastern Ukrainian Caucasian men with abnormally low ...the FSHR gene in genotype and degree of DNA frag- mentation is ...
8
ASSOCIATION OF FSHR GENE POLYMORPHISM WITH POLYCYSTIC OVARY SYNDROME IN IRAQI WOMEN
... between FSHR gene polymorphism and Polycystic Ovary Syndrome in Iraqi women using polymerase chain reaction –restriction fragment length polymorphism ...of FSHR gene that contains the SNP ...
6
Investigation of the polymorphism in FSHR gene associated with fertility in pregnant and non-pregnant Iraq buffaloes
... © 2017; AIZEON Publishers; All Rights Reserved This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any ...
5
THE ROLE OF GENE THERAPY IN PREMATURE OVARIAN INSUFFICIENCY MANAGEMENT
... (FSHR) gene polymorphisms, chromosomal defects, autoimmune and enzymatic disorders are among the known ...(7), FSHR (8), FOXL2 (9), GDF9 (4), NOBOX (10), INHA (11), STAG3 (12) are the examples of ...
17
Evaluating influence of the genotypes in the follicle-stimulating hormone receptor (FSHR) Ser680Asn (rs6166) polymorphism on poor and hyper-responders to ovarian stimulation: a meta-analysis
... The FSHR gene is located on chromosome 2p21 spanning a region of 54 kb [17] and contains one large exon, which encodes the transmembrane and intracellular domains; and nine smaller exons, which encode the ...
11
Fertility Preservation in Premature Ovarian Insufficiency (POI) Secondary to FSH Receptor Gene (FSHR) Mutation: Is There a New Hope?
... A 19 years old patient with primary amenorrhea was referred to our center. Based on discrepancy between high follicle stimulating hormone (FSH) level and normal ovarian reserve parameters, follicle stimulating hormone ...
7
Original Article Molecular expression and localization of follicle-stimulating hormone and its receptor in rat liver
... and FSHR immunofluorescent positive sub- stances in rat liver cells, which indicated FSH and FSHR expression in rat liver ...and FSHR expression in liver ...and FSHR in liver cells from ...
6
Original Article Expression and localization of rat stomach follicle stimulating hormone and its receptor and analysis of core segments sequence
... the gene sequence characteristics in order to provide a theoretical basis for further study on gastric FSH functional ...cloned gene and sequencing of the core gene cDNA fragments were obtained and ...
7
Follicle stimulating hormone modulates ovarian stem cells through alternately spliced receptor variant FSH-R3
... If indeed FSH-R3 (which lacks exon 10) is the key player to mediate FSH action on stem cells resulting in neo- oogenesis during postnatal life, one could easily explain why the extensive studies undertaken to search for ...
15
The frequency of follicle stimulating hormone receptor gene polymorphisms in Iranian infertile men with azoospermia
... a FSHR gene on male ...and FSHR polymorphism at position A2039G ...the FSHR gene might affect male reproductive parameter ...receptor gene were not a common cause of infertility ...
6
Endometrial mesenchymal stem cells isolated from menstrual blood repaired epirubicin-induced damage to human ovarian granulosa cells by inhibiting the expression of Gadd45b in cell cycle pathway
... assay; FSHR: Follicle-stimulating hormone receptors; Gadd45: Growth arrest and DNA damage inducible gene; GCs: Granulosa cells; GnRH: Gonadotropin-releasing hormones; HCG: Human chorionic gonadotropin; HRT: ...
10
Expression of hypothalamic-pituitary-gonadal axis-related hormone receptors in low-grade serous ovarian cancer (LGSC)
... two experienced gynecologic pathologists. A microarray (1 mm) using triplicate tissue samples from each tumor was prepared [17, 18]. Sections (3 μm) of the completed tissue microarray were analyzed by standard immunohis- ...
8
Gonadotropin treatment augments postnatal oogenesis and primordial follicle assembly in adult mouse ovaries?
... The Q-PCR data obtained by analysis of control and PMSG treated ovaries is presented (Figure 10). As expected, a sig- nificant increase in Fshr mRNA expression was noted on 2D after PMSG treatment compared to ...
14
Towards gene network estimation with structure learning
... of gene interactions. A gene usually collaborates with other genes in order to ...analyse gene expression data, other researchers have enhanced the technique ...the gene network is ...
5
Development and application of a bioassay for follicle stimulating hormone : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology at Massey University
... Fig 5.5 Comparison of bioactive FSH concentrations obtained by CHO FSHR-R cell bioassay • and FSH concentrations obtained by radio receptor assay D and radioimmunoassay ~ in HPLC fract[r] ...
145
Clinical and Hormonal Profile of Hypogonadism
... • Aromatase deficiency Gonadotropin/receptor mutations FSH beta, LHR, FSHR • Androgen resistance syndrome Hypogonadotropic hypogonadism GENETIC • Hypothalamic syndromes due to mutation o[r] ...
105
Development and application of a bioassay for follicle stimulating hormone : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology at Massey University
... Comparison of bioactive FSH concentrations obtained by CHO FSHR-R cell bioassay and FSH concentrations obtained by radio receptor assay and radioimmunoassay in HPLC fractions of purified[r] ...
36
Structure and activation of the TSH receptor transmembrane domain
... Tables 2, 3 and 4 show a list of GPHR CAMs taken from the literature, whereas Supplementary Tables 1–3 list the main interactions involving the mutated residues of the CAMs as observed in the comparative models of the ...
18
GnRH-agonist implants suppress reproductive function and affects ovarian LHR and FSHR expression in prepubertal female cats
... In conclusion, the results of this study have demonstrated that in prepubertal queens, a subcutaneous implant of 4.7-mg deslorelin suppresses ovarian weight, follicle development, estrogen production, and myometrial ...
20
Targeted gene silencing using a follicle-stimulating hormone peptide-conjugated nanoparticle system improves its specificity and efficacy in ovarian clear cell carcinoma in vitro
... a FSHR-mediated delivery system could mediate the highly selective delivery of siRNA into ovarian cancer cells and that silencing gro- α expression could be a potential choice for ovarian cancer ...
9