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New Insight into Filamentous Hemagglutinin Secretion Reveals a Role for Full Length FhaB in Bordetella Virulence

New Insight into Filamentous Hemagglutinin Secretion Reveals a Role for Full Length FhaB in Bordetella Virulence

... completely cleared this strain from their trachea and lungs by 11 days postinoculation (Fig. 4a). However, the course of infec- tion of the ⌬ ECT strain differed from that of the FHA-null strain; there was no increase in ...

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Association between circulating full-length angiopoietin-like protein 8 and non-high-density lipoprotein cholesterol levels in Chinese non-diabetic individuals: a cross-sectional study

Association between circulating full-length angiopoietin-like protein 8 and non-high-density lipoprotein cholesterol levels in Chinese non-diabetic individuals: a cross-sectional study

... culating full-length ANGPTL8 levels and serum ...ing full-length ANGPTL8 concentrations, circulating full-length ANGPTL8 concentrations were positively as- sociated with serum TG ...

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Enhancing full-length antibody production by signal peptide engineering

Enhancing full-length antibody production by signal peptide engineering

... the newly synthesized signal peptide at the ribosome and directs the ribosome-nascent chain (RNC) complex to the SRP receptor FtsY. The RNCs are then targeted to the SecYEG translocon where translocation occurs simulta- ...

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Full length genome and molecular characterization of dengue virus serotype 2 isolated from an imported patient from Myanmar

Full length genome and molecular characterization of dengue virus serotype 2 isolated from an imported patient from Myanmar

... The full-length sequence of the YNPE2 strain was assembled by SPAdes software based on the RNA-seq data and the referenced genome of DENV-2 ...assembled full-length sequence of YNPE2 was ...

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The preparation of an infectious full length cDNA clone of Saffold virus

The preparation of an infectious full length cDNA clone of Saffold virus

... a full-length clone, viral RNA was extracted from JPN08-404 propagated in HeLa cells using RNeasy mini kit (QIAGEN) according to the manufacturer ’ s ...The full- length clones were generated ...

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A Full Length Infectious cDNA Clone of Zika Virus from the 2015 Epidemic in Brazil as a Genetic Platform for Studies of Virus Host Interactions and Vaccine Development

A Full Length Infectious cDNA Clone of Zika Virus from the 2015 Epidemic in Brazil as a Genetic Platform for Studies of Virus Host Interactions and Vaccine Development

... a full-length genome by in vitro ligation (25), (iv) insertion of linker sequences that disrupt the viral open reading frame and are removed prior to transcrip- tion (26), and (v) the use of homologous ...

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Identification of a Full-Length cDNA for an Endogenous Retrovirus of Miniature Swine

Identification of a Full-Length cDNA for an Endogenous Retrovirus of Miniature Swine

... of full-length sequence data for endogenous retro- virus of swine may allow the investigation of viral activation and transmission in studies of xenotransplantation and pro- vides tools for detection of ...

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Identification of diverse full length endogenous betaretroviruses in megabats and microbats

Identification of diverse full length endogenous betaretroviruses in megabats and microbats

... Our analysis of the full-length bat βERVs revealed an un- expected diversity of genomic organizations, as a num- ber were found to contain unique ORFs. Some of these ORFs were in alternative reading frames ...

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Identification, Molecular Cloning, and Analysis of Full Length Hepatitis C Virus Transmitted/Founder Genotypes 1, 3, and 4

Identification, Molecular Cloning, and Analysis of Full Length Hepatitis C Virus Transmitted/Founder Genotypes 1, 3, and 4

... While it was not the original focus of our study, we had a unique opportunity to look with great sensitivity and specificity for viral recombination in subjects acutely infected by more than one genetically distinct ...

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Stability and flexibility of full length human oligodendrocytic QKI6

Stability and flexibility of full length human oligodendrocytic QKI6

... Results: We expressed and purified full-length QKI6 and characterized it using mass spectrometry, light scattering, small-angle X-ray scattering, and circular dichroism spectroscopy. QKI6 was monodisperse, ...

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Characterization of a Pathogenic Full Length cDNA Clone and Transmission Model for Porcine Epidemic Diarrhea Virus Strain PC22A

Characterization of a Pathogenic Full Length cDNA Clone and Transmission Model for Porcine Epidemic Diarrhea Virus Strain PC22A

... of full-length recombinant ...the full-length infectious ...and full- length T7 RNA transcripts were generated as described in the mMessage mMachine manufacturer protocol ...

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Soluble expression, purification and characterization of the full length IS2 Transposase

Soluble expression, purification and characterization of the full length IS2 Transposase

... of full length native or GFP-tagged IS2 TPase, purified to homogene- ity, contrasts starkly with the extremely efficient binding of the partially purified OrfAB-GFP utilizing residues at both the N- and ...

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On Reinforcement Learning for Full-Length Game of StarCraft

On Reinforcement Learning for Full-Length Game of StarCraft

... StarCraft II poses a grand challenge for reinforcement learn- ing. The main difficulties include huge state space, varying action space, long horizon, etc. In this paper, we investigate a set of techniques of ...

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Answering Naturally: Factoid to Full length Answer Generation

Answering Naturally: Factoid to Full length Answer Generation

... long phrasal factoid answers from which the sys- tem has to learn to copy and generate words as needed. Table 7 shows that the pointer-generator system handles tense agreement and generation of new words. The Seq2Seq ...

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Full length Ebola glycoprotein accumulates in the endoplasmic reticulum

Full length Ebola glycoprotein accumulates in the endoplasmic reticulum

... with full-length and mucin-deleted ( Δ mucin) Ebola GP plasmids and GP localization was examined relative to the nucleus, endoplasmic reticulum (ER), Golgi, early and late endosomes using deconvolution ...

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Nucleotide sequence of a full-length human endogenous retroviral segment.

Nucleotide sequence of a full-length human endogenous retroviral segment.

... The nucleotide sequence of a second human retroviral clone 4-14 was determined in the same region data not shown, and both the 12-amino-acid insertion and the same 11-of-14 deduced amino[r] ...

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Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity.

Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity.

... with full-length Nef for bind- ing to MAPK (Table ...to full-length Nef was inhibited with peptide 69 to 83 in a concentration-depen- dent manner, with 50% inhibition occurring when a 3-fold ...

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Association of CHMP4B and autophagy with micronuclei : implications for cataract formation

Association of CHMP4B and autophagy with micronuclei : implications for cataract formation

... FLAG-CHMP4B full length construct wild type or FLAG-CHMP4B full length construct which contained the mutation D129V found in patients with cataract and in both cases, among the trans- fected ...

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Identification of a new polypeptide coded by reovirus gene S1.

Identification of a new polypeptide coded by reovirus gene S1.

... However, to determine if the full-length sl mRNA could be translated in vitro to yield both a 1 and C s, we subcloned the entire Si gene into plasmid pSP64 and synthesized a full-length [r] ...

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Interaction of Kaposi's Sarcoma-Associated Herpesvirus ORF6 Protein with Single-Stranded DNA

Interaction of Kaposi's Sarcoma-Associated Herpesvirus ORF6 Protein with Single-Stranded DNA

... of full-length ORF6 and ORF6⌬C to ssDNA, we employed electrophoretic mobility shift assays ...in length, labeled with 5=-flu- ...substrate, full-length ORF6 formed two supershifted ...

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