Function of Brown adipose tissue
Non-invasive Imaging Methods for Brown Adipose Tissue Detection and Function Evaluation
... Abstract Brown Adipose Tissue (BAT) has a major role in thermoregulation, producing heat by non-shivering ...significant brown adipose tissue was identified only recently, and ...
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Original Article PRDM16 inhibits atherosclerosis plaque forming through enhancing the function of periaortic brown adipose tissue
... and adipose surrounding artery of rats was ...in adipose rounding abdominal aorta were determined by ...PRDM16-induced brown adipose cells were co-cultured with mac- ...White adipose ...
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Intracellular conversion of thyroxine to triiodothyronine is required for the optimal thermogenic function of brown adipose tissue
... protein (UCP) in rat brown adipose tissue (BAT) has been examined. Thyroidectomized rats have a threefold reduction in basal UCP levels. When exposed to cold, they become hypothermic and show a ...
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Sexual dimorphism of brown adipose tissue function
... thermogenic tissue contributes to energy expenditure by oxidising lipids and glucose 4-7 ...the adipose tissue surrounding the heart 10 and kidneys 8, 11 as well as subcutaneously 11 ...white ...
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Novel insights in imaging and function of human brown adipose tissue
... white adipose tissue (WAT), which stores excess energy, brown adipose tissue (BAT) dissipates chemical energy in the form of heat by uncoupling oxidative phosphorylation from electron ...
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SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function
... in-depth tissue analyses revealed that enhanced insulin sensitivity was achieved through a higher brown adipose tissue activity and was fully reversed by housing the mice at ...fluence ...
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Insights into brown adipose tissue evolution and function from non model organisms
... More than 40 years later, it transpires that these studies, although missing molecular data, were well performed and provided accurate predictions for most placental mammals. The authors themselves made the humble final ...
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Recent progress in the study of brown adipose tissue
... Abstract Brown adipose tissue in mammals plays a critical role in maintaining energy balance by thermogenesis, which means dissipating energy in the form of ...energy-dissipating function of ...
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Brown adipose tissue: endocrine determinants of function and therapeutic manipulation as a novel treatment strategy for obesity
... The physiological effects of TH are exerted at the level of transcription through the thyroid receptors (TR): TRα and TRβ [42]. TRβ mediates thyronine (T3) induced UCP1 gene expression, whilst the TRα isoform through T3 ...
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Long noncoding RNA H19 protects from dietary obesity by promoting brown adipose tissue commitment and function
... inhibitor were added. The samples were vortexed and incubated for 5 min on ice. PBS and protease inhibitor were added in equal amounts to the nuclear suspension and vortexed. A tip sonicator was used to lyse the residual ...
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Brown adipose tissue
... Keywords: brown adipose tissue, thermogenesis, UCP1, mitochondria, BATokine, browning, adipogenesis Obesity is currently a global pandemic and is associated with increased mortality and ...
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INDUCTION OF BROWN ADIPOSE TISSUE: A REVIEW
... Methods: Understanding the regulators, activators and secreted proteins which induce browning of WAT to BAT, as the BAT engage in thermogenesis process and transform fat into heat rather than storing it (WAT). Some of ...
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Brown and Beige Adipose Tissue and Aging
... aging, adipose tissue (AT) changes its quantity and distribution: AT becomes dysfunctional with an increase in production of inflammatory peptides, a decline of those with anti-inflammatory activity and ...
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Brown adipose tissue: is it affected by intermittent hypoxia?
... Brown adipose tissue (BAT) function may be involved in obesity [5]. BAT produces heat through the action of uncoupling protein 1 (UCP1) [6]. During exposure to cold, UCP1 is physiologically ...
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Cold induced changes in gene expression in brown adipose tissue, white adipose tissue and liver
... noted that recent studies have emphasised that 22uC is still below thermoneutrality so the room temperature acclimated mice are effectively mildly cold stressed [31]. A striking finding in this study is that the GO ...
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Function and activation of human adipose tissue: The role of genes in the link between physical activity and brown adipose-like phenotype
... white adipose tissue (WAT) in humans is considered as a harmful health ...increased brown adipose tissue (BAT) and brown-like adipose tissue activity are associated ...
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Identification and characterization of a supraclavicular brown adipose tissue in mice
... Surprisingly, the two main BAT depots found in adult humans, scBAT and deep neck BAT, have not been reported in mice. Instead, most mouse studies focus on iBAT, which is only present during infancy in humans (22). This ...
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Brown adipose tissue thermogenic capacity is regulated by Elovl6
... in brown and beige adipocytes, two previous publications (Matsuzaka et ...mitochondrial function in ...mitochondrial function in ...in brown fat can be detected by either maximally activating ...
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Studying Brown Adipose Tissue in a Human in vitro Context
... pandemic. Brown adipose tissue (BAT) may represent a promising therapeutic target to treat obesity, as this tissue has been shown to regulate energy expenditure through non-shivering ...BAT ...
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Heterogeneity of adipose tissue in development and metabolic function
... in adipose tissue can result in impaired adipose tissue function, characterized by altered adipokine secretion, tissue inflammation, and the spillover of lipids into other ...
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