The future for negative-sense RNA
Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families
... and negative-sense RNA viruses in spe- cific tissues, including the brain and lungs (20, ...45). Future studies are needed to determine if human and mouse IFIT2 proteins re- strict IAV, LACV, ...
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Human And Murine Ifit1 Proteins Do Not Restrict Infection Of Negative-sense Rna Viruses Of The Orthomyxoviridae, Bunyaviridae, And Filoviridae Families
... and negative-sense RNA viruses in spe- cific tissues, including the brain and lungs (20, ...45). Future studies are needed to determine if human and mouse IFIT2 proteins re- strict IAV, LACV, ...
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RNA synthesis initiation by the nonsegmented negative-sense RNA virus polymerases
... in RNA synthesis As discussed above, our data is consistent with RSV L P1261 functioning as the priming ...the RNA product and template to perform multiple rounds of RNA ...and RNA product ...
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A case for a negative-strand coding sequence in a group of positive-sense RNA viruses.
... the negative strand of any (þ)ssRNA vi- ...in RNA virus sequences that are statistically significantly longer than expected by chance, with the assump- tion being that such ORFs are likely to be functional ...
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Investigation of the control of coronavirus subgenomic mRNA transcription by using T7-generated negative-sense RNA transcripts.
... leader RNA sequence, the TGEV leader sequence must have been derived from the virus, ...leader RNA was fused downstream of the ...the RNA within the TAS, presumably at the ACUAAAC sequence, according ...
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Making sense of Dlx1 antisense RNA
... Dlx1as RNA ( McGuinness et ...Dlx1as RNA. Here, to investigate any possible function of the Dlx1as RNA, we truncated the Dlx1as RNA using gene targeting to abolish Dlx1as expression and hence ...
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The family Rhabdoviridae: mono- and bipartite negative-sense RNA viruses with diverse genome organization and common evolutionary origins
... Figure legends Fig. 1. A. (left half of figure). Schematic representation of rhabdovirus particle internal structure. The single-stranded negative-sense genomic RNA is encapsidated along its entire ...
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Common Mechanism for RNA Encapsidation by Negative-Strand RNA Viruses
... versus N-terminal domains of each viral N protein (11). The con- tact areas between neighboring domains in different NLPs are listed in Table 3. The contact areas must have plasticity because these calculated contact ...
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A Conserved Motif in Region V of the Large Polymerase Proteins of Nonsegmented Negative-Sense RNA Viruses That Is Essential for mRNA Capping
... Nonsegmented negative-sense (NNS) RNA viruses cap their mRNA by an unconventional ...an RNA triphos- phatase and ...intermediate. RNA guanylyltransferases typically have a KxDG motif in ...
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A Conserved Motif in Region V of the Large Polymerase Proteins of Nonsegmented Negative-Sense RNA Viruses That Is Essential for mRNA Capping
... Nonsegmented negative-sense (NNS) RNA viruses cap their mRNA by an unconventional ...an RNA triphos- phatase and ...intermediate. RNA guanylyltransferases typically have a KxDG motif in ...
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Octapartite negative-sense RNA genome of \u3c/i\u3eHigh Plains wheat mosaic virus\u3c/i\u3e encodes two suppressors of RNA silencing
... However, RNA 1 encodes for replication-associated proteins, thus it is unlikely that RNA 1 encodes a domain with suppression of RNA silen- cing ...by RNA 7 (P7) and 8 (P8), but not their RNAs, ...
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Octapartite negative-sense RNA genome of \u3c/i\u3eHigh Plains wheat mosaic virus\u3c/i\u3e encodes two suppressors of RNA silencing
... However, RNA 1 encodes for replication-associated proteins, thus it is unlikely that RNA 1 encodes a domain with suppression of RNA silen- cing ...by RNA 7 (P7) and 8 (P8), but not their RNAs, ...
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RNA Binding Properties of Bunyamwera Virus Nucleocapsid Protein and Selective Binding to an Element in the 5′ Terminus of the Negative-Sense S Segment
... mologous RNA may be due to interactions between the 5⬘ and 3⬘ termini of BUNS5⬘(32)/3⬘(33) such that the labeled RNA is able to base-pair with unlabeled homologous RNA to form multimers, thereby ...
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Constraints of Viral RNA Synthesis on Codon Usage of Negative-Strand RNA Virus
... ABSTRACT Negative-strand RNA viruses (NSVs) include some of the most patho- genic human viruses ...NSV RNA synthesis in that the genomic RNA sequestered in the nucleocapsid serves as the ...
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Making Sense of the Future of Post-Secondary Education
... credentials, policies and practices. (Wilson, Morrell & Hargrave, 2012, p. 21) The preceding paragraphs represents a glimpse of drivers and trends that are existent in the contextual environment concerning the ...
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Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements.
... (+)-sense RNA viruses, RNA struc- tural elements (SEs) play essential roles in the infec- tion process from replication to ...of RNA structure in viral ...
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Subgenomic RNA as a riboregulator: negative regulation of RNA replication by Barley yellow dwarf virus subgenomic RNA 2
... Surprisingly, the replication of BYDV was not inhibited as much when the molar ratio of BTE/PAV6 was increased to 20:1 and 40:1. One possible explanation for this result is that, at these higher concentrations, the BTE ...
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RNA Interference: Past, Present and Future
... RNAi: Past Prior to the discovery of RNAi, several other previously characterized, homology-dependent gene silencing mechanisms had been described. In 1990, the Jorgensen laboratory introduced exogenous transgenes into ...
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Architecture and RNA binding of the human negative elongation factor
... shaped RNA produced +59 nucleotides after Pol II initiates transcription from the HIV-1 long termi- nal repeat of the integrated HIV-1 virus ( Karn and Stoltzfus, 2012 ) ( Figure 7C ...TAR RNA is used to ...
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The sense of coherence in imagined future narratives : a qualitative analysis
... ideal future, and sharing was seen as a non-neglectable component of this future, as for example in this statement “Sharing is the principal way of ...the future, exemplified by these statements: ...
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