G-CSF treatment
Targeting stem cell niche can protect hematopoietic stem cells from chemotherapy and G-CSF treatment
... donors, G-CSF significantly increases the num- ber of HSCs in PB, but suppresses the number and the activities of osteoblasts in the meantime [5, 29, ...by G-CSF-induced mobilization of HSPCs ...
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An extended window of opportunity for G-CSF treatment in cerebral ischemia
... of G-CSF treatment we applied photothrombotic induction of ischemia in the sensorimotor cortex, as this model produces defined neu- rological deficits without affecting ...of G-CSF on ...
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Anti-G-CSF treatment induces protective tumor immunity in mouse colon cancer by promoting NK cell, macrophage and T cell responses
... that G-CSF stimulated human CRC cell growth and migration, therefore in this study we sought to examine the therapeutic potential of anti-G-CSF treatment for ...CRC. G-CSF ...
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Sweet Syndrome Associated With G-CSF Treatment in a Child With Glycogen Storage Disease Type Ib
... dysfunction by granulocyte colony-stimulating factor in a patient with glycogen storage disease type Lb. Schroten H, Roesler J, Breidenbach T, et al[r] ...
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Pharmacokinetic and -dynamic modelling of G-CSF derivatives in humans
... and G-CSF induced granulocytosis via different modes of action in combination with a strong specific elimination of G-CSF mediated by circulating granulocytes results in complex dynamics of ...
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RESEARCH ARTICLE Granulocyte-colony stimulating factor in neonatal sepsis with leukopenia: A prospective cohort study
... given G-CSF in a dose of 12 micrograms per kg per day subcutaneously in two divided doses irrespective of the ...point G-CSF was stopped. Duration of G-CSF treatment and ...
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Small Molecules that Mimic or Antagonize Actions of Granulocyte Colony- Stimulating Factor (G-CSF)
... that G-CSF acts directly on neural tissue has stimulated research on the therapeutic applications of these agents for neurodegenerative diseases, stroke and brain trauma ...[9-12]. G-CSF ...
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The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus
... defective G- CSFR signaling and is responsible for the differential autoimmune response between B6 and ...However, G-CSF treatment did not induce bm12-cGVHD resistance in B6 mice, but instead ...
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Treatment with G-CSF reduces acute myeloid leukemia blast viability in the presence of bone marrow stroma
... of G-CSF with induction chemotherapy reported in previous clini- cal studies was mainly observed in the subset of patients with a cytogenetic intermediate-risk AML ...to G-CSF treatment ...
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Study of functional features of neutrophils induced by granulocyte colony stimulating factor [G CSF] during chemotherapy in cancer patients
... Following treatment with G CSF during chemotherapy Neutrophil count improved significantly and was comparable to Normal ...Following G CSF treatment Superoxide production by ...
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A Simulations and Data Fit Mathematical Modeling of G CSF Drug Treatment
... The treatment protocols typically call for daily subcutaneous injection of G-CSF at 3 to 5 µg per kg of body ...under G-CSF treatment, the neutrophil count could be stabilized or ...
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Investigation of the molecular pathogenesis of Kostmann's syndrome
... the G-CSFR ...functional G- CSFR exists as a homodimer and thus such results suggested that the mutated chain was acting in a dominant negative fashion, a mechanism postulated previously for several other ...
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Identification of a functional receptor for granulocyte colony stimulating factor on platelets
... that G-CSF receptors are present on platelets. The expression of G-CSF receptors on platelets was demonstrated by flow cytometry and radioreceptor ...of G-CSF-binding sites per ...
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Comparative effects of granulocyte-colony stimulating factor and colistin-alone or in combination on burn wound healing in Acinetobacter baumannii infected mice
... healing. G-CSF can help in the wound healing by reducing translocation and colonization of the bacteria, and increasing blood neutrophils (23, ...addition, G-CSF can increase the number of ...
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G-CSF Intrauterine for Thin Endometrium, and Pregnancy Outcome
... At first, ovaries were stimulated with a standard protocol (GnRH Agonist /GONAL-f ®, Merck Serono, Germany) or GnRH Antagonist /GONAL-f). When at least two follicles achieved 18mm diameter, Human chorionic gonadotropin ...
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The Role of Donor Leukocyte Infusions in the Treatment of Relapsed Acute Leukemia after Allogeneic Stem Cell Transplantation: A Retrospective Analysis
... of treatment and, especially GVL enhancing modalities like DLI and their survival benefits, should be considered as one of the best existing approaches for an inevitably, extremely fatal ...
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Growth factor release by vesicular phospholipid gels: in vitro results and application for rotator cuff repair in a rat model
... A previous study has shown that continuous release of G-CSF via an osmotic pump positively affected the supraspinatus tendon (SSP) remodeling in a chronic SSP tear rat model [10]. Nevertheless, the rate of ...
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Recombinant Granulocyte Colony-Stimulating Factor Administered Enterally to Neonates Is Not Absorbed
... was detected in the plasma of neonates after swal- lowing such a pharmacologic dose, absorption was unlikely to occur after swallowing physiologic quan- tities. We conclude that rhG-CSF administered orally to ...
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A randomized study comparing chemotherapy followed by G-CSF alone or in combination with GM-CSF for mobilization of peripheral blood stem cells in patients with non-Hodgkin’s lymphomas
... either G-CSF or G-CSF plus GM-CSF (G+GM) starting 24 hours after completion of chemotherapy and continuing until completion of ...
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G-CSF associates with neurogenesis and predicts prognosis and sensitivity to chemotherapy in pancreatic ductal adenocarcinoma
... specimens, G-CSF was discovered predominantly in the cell cytoplasm and expressed in most of PDAC, while in plasma, the systemic level of G-CSF is no different between normal patients and ...
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