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Gastrointestinal Malignancies

Aurora Kinase A and Gastrointestinal Malignancies

Aurora Kinase A and Gastrointestinal Malignancies

... Aurora kinase A (AURKA) has emerged as a potential therapeutic target in gastrointestinal malignancies. It has been shown to not only regulate the process of mitosis, but also to have critical non-mitotic ...

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Pattern of Upper Gastrointestinal Malignancies as Seen at Endoscopy in Ekiti State University Teaching Hospital, Ado Ekiti, Nigeria

Pattern of Upper Gastrointestinal Malignancies as Seen at Endoscopy in Ekiti State University Teaching Hospital, Ado Ekiti, Nigeria

... The gastrointestinal (GI) tract along with its accessory glands is one of the most common systems of the human body affected by various cancers ...upper gastrointestinal malignancies varies widely ...

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Estrogen Receptor Status in Upper Gastrointestinal Malignancies

Estrogen Receptor Status in Upper Gastrointestinal Malignancies

... upper gastrointestinal malignancies are from Japan and few from Western Countries that too mostly proven in animal ...upper gastrointestinal malignancies in this part of the ...

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Off-label use of common predictive biomarkers in gastrointestinal malignancies: a critical appraisal

Off-label use of common predictive biomarkers in gastrointestinal malignancies: a critical appraisal

... in gastrointestinal malignancies, we reviewed the literature and offer recommendations on an algorith- mic approach to these biomarkers in the digestive ...the gastrointestinal sites to help ...

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Antiangiogenic agents in advanced gastrointestinal malignancies: past, present and a novel future

Antiangiogenic agents in advanced gastrointestinal malignancies: past, present and a novel future

... solid malignancies who had failed standard of care treatments report good tolerability at doses <300mg ...human malignancies, clinical development of AZ6474 has been across multiple tumor ...

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Effect of timing of pharmaconutrition (immunonutrition) administration on outcomes of elective surgery for gastrointestinal malignancies: a systematic review and meta-analysis

Effect of timing of pharmaconutrition (immunonutrition) administration on outcomes of elective surgery for gastrointestinal malignancies: a systematic review and meta-analysis

... pharmaconutrition and provides further insight into the effects of its use. Firstly it continues to show no adverse effect on postoperative mortality in elective gastrointestinal surgical populations. It also ...

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Combination regimens with PD-1/PD-L1 immune checkpoint inhibitors for gastrointestinal malignancies

Combination regimens with PD-1/PD-L1 immune checkpoint inhibitors for gastrointestinal malignancies

... Gastrointestinal (GI) malignant neoplasms have a high global incidence and treatment prospects for patients with advanced GI tumors are dismal. PD-1/PD-L1 inhibitors emerged as a frontline treatment for several ...

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Role of modern immunotherapy in gastrointestinal malignancies: a review of current clinical progress

Role of modern immunotherapy in gastrointestinal malignancies: a review of current clinical progress

... Wilms’ tumor gene (WT1) is overexpressed in several malignancies including PDAC. The efficacy of WT1 pep- tide vaccine plus gemcitabine was examined in a ran- domized phase II study of locally advanced or advanced ...

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Laparoscopic T-tube feeding jejunostomy as an adjunct to staging laparoscopy for upper gastrointestinal malignancies: the technique and review of outcomes

Laparoscopic T-tube feeding jejunostomy as an adjunct to staging laparoscopy for upper gastrointestinal malignancies: the technique and review of outcomes

... It is a technique commonly involves a commer- cial product [9 – 11], with percutaneous placement of feed- ing catheter performed after the bowel is secured to the abdominal wall, using a[r] ...

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Gastrointestinal malignancies harbor actionable MET exon 14 deletions

Gastrointestinal malignancies harbor actionable MET exon 14 deletions

... In two PDC cell lines with METex14del+ without concurrent MET amplification, tumor growths were profoundly inhibited by both MET tyrosine kinase inhibitors and a MET targeting monoclonal antibody-. Our study is the first ...

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Endoscopic Biopsy Yield in Upper Gastrointestinal Malignancies

Endoscopic Biopsy Yield in Upper Gastrointestinal Malignancies

... NAME AGE/SEX ENDOSCOPIC DIAGNOSIS TOTAL BIOPSY SAMPLES BIOPSY REPORT JANAKI RAMALINGAM JAYANTHI RAJAGOPAL 38/F 62/M 58/F 47/M LOWER ESOHAGUS GROWTH MID ESOPHAGUS GROWTH LOWER ESOPHAGUS G[r] ...

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To study the spectrum of Gastrointestinal and Hepato-Pancreato-Biliary Tract Malignancies at a Tertiary Centre in South India.

To study the spectrum of Gastrointestinal and Hepato-Pancreato-Biliary Tract Malignancies at a Tertiary Centre in South India.

... chemotherapy, gastrointestinal malignancy remains ...most gastrointestinal malignancies are diagnosed in late stage with regional and distant ...prevention. Gastrointestinal ...

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Feasibility of enhanced recovery after surgery in gastric surgery: a retrospective study

Feasibility of enhanced recovery after surgery in gastric surgery: a retrospective study

... Among the many elements of ERAS programs, one of the utmost concerns for surgeons is that early postoper- ative feeding can induce postoperative ileus or anasto- mosis leakage. Because of these concerns, oral intake of ...

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Role of expression of P63 and calponin in gastro-intestinal tract carcinomas

Role of expression of P63 and calponin in gastro-intestinal tract carcinomas

... Gastrointestinal malignancies are increasing in incidence due to various risk factors and life style modifications in our ...country. Gastrointestinal malignancies are seen in wide range of ...

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Drug waste minimisation and cost containment in Medical Oncology: Two year results of a feasibility study

Drug waste minimisation and cost containment in Medical Oncology: Two year results of a feasibility study

... for gastrointestinal malignancies to take place on Monday and Wednesday, those for thoracic malignan- cies on Tuesday, and breast cancer treatment sessions on Thursday and ...

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Glyoxalases in Urological Malignancies

Glyoxalases in Urological Malignancies

... urological malignancies, including hypoxia, hormone influence, genetic predisposition, oxidative and glycative stresses and inflammation ...urogenital malignancies and Glyoxalases potential as targets for ...

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Immunotherapy in genitourinary malignancies

Immunotherapy in genitourinary malignancies

... Treatment of cancer patients involves a multidisciplinary approach including surgery, radiotherapy, and chemotherapy. Traditionally, patients with metastatic disease are treated with combination chemotherapies or ...

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A Study of Thyroid Malignancies

A Study of Thyroid Malignancies

... Controversy still exists over the treatment of this cancer because of the long term survival of patients with differentiated thyroid cancers irrespective of the type or extent of treatme[r] ...

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PET in uterine malignancies

PET in uterine malignancies

... These malignancies present an extremely poor prognosis and, despite their rarity, they are responsible for a large number of deaths every year, in women with uterine ...

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Evaluation of the new TNM staging system for thymic malignancies: impact on indication and survival

Evaluation of the new TNM staging system for thymic malignancies: impact on indication and survival

... The tumor–node–metastasis (TNM) classification of can- cers proposed by the UICC is used worldwide and ac- cepted as a uniform classification system. It provides a stage-adapted indication system for therapy and helps to ...

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