Gene expression analysis in Wnt signalling networks
SoxB1 transcription factors restrict organizer gene expression by repressing multiple events downstream of Wnt signalling
... ectopic expression of organizer markers and the formation of a duplicated ...early expression of Sox3 throughout the epiblast and early ectoderm provides a mechanism to restrict organizer formation to the ...
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Gene expression analysis of potential morphogen signalling modifying factors in Panarthropoda
... embryonic expression profiles of most of the MMFs investigated here, such as dally differ among all investigated species, and there is only little potentially “conserved” ...is expression in the head in all ...
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An analysis of wnt signalling molecules in Xenopus pronephros development
... 5.4 wnt Holtfreter sandwich cultures assayed for somite ...in wnt Holtfreter sandwich cultures could result from formation of somites which themselves are able to induce pronephric ...specific wnt ...
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Changes in the expression of Notch and Wnt signalling molecules in human endometrial cancer
... the expression profile of Notch and Wnt pathways signalling molecules and determine the relationship between both sys- tems in endometrial cancer ...DLL1, Wnt signalling trans- ductor ...
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Genetic analysis of hedgehog signalling and the regulation of patched gene expression in vertebrate embryos
... ptcl expression at late somitogenesis stages are similar to those of either yot or syu, expression being almost completely eliminated from the CNS and ...myoD expression than is seen in yot ...hh ...
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Wnt signalling: conquering complexity
... robust signalling response (Jho et ...Tcf/Lef-dependent gene expression changes are arguably the most studied response to Wnt ligand binding in a target ...physiological Wnt pathway ...
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WNT signalling in prostate cancer
... immunohistochemical analysis dectected high expression of WNT-1 to be highly expressed in prostate cancer cell lines, primary tumours and metastases 91 ...noncanonical WNT signalling in ...
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Data Analysis of Expression with Gene Microarray and Investigation for Gene Regulatory Networks
... of analysis of gene microarray data, and point out that many existed methods have some weakness including low capability of dealing with redundant and noisy data, unexplained mining results and limited ...
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Upregulation of human PINK1 gene expression by NFκB signalling
... PINK1 gene into a promoterless vector up- stream of a reporter luciferase ...PINK1 gene promoter. Subsequently, by dele- tion analysis we found that the 104 bp fragment from −78 to 26 serves as the ...
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Wnt signalling in lung development and diseases
... 110. Bühling F, Röcken C, Brasch F, Hartig R, Yasuda Y, Saftig P, Brömme D, Welte T: Pivotal Role of Cathepsin K in Lung Fibrosis. Am J Pathol 2004, 164:2203-2216. 111. Zuo F, Kaminski N, Eugui E, Allard J, Yakhini Z, ...
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The WNT signalling pathway in colorectal cancer
... 1.6.4.9 WNT/β-catenin target genes in colorectal tumours Aberrant WNT/β-catenin signalling in colorectal neoplasms drives tumourigenesis through altered gene ...of WNT signalling ...
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Wnt signalling and cancer stem cells
... the Wnt signalling pathways, such as with transcription factor 7-like 2 gene (TCF7L2), may impart increased risk for type 2 DM in some populations [106] as well as have increased association with ...
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Using Biological Networks and Gene-Expression Profiles for the Analysis of Diseases
... microarray analysis using pathway databases to situations where the dataset contains only a small number of sam- ...in gene-expression values of the two phenotypes in isolated subnetworks ...
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Expression of osterix Is Regulated by FGF and Wnt/β-Catenin Signalling during Osteoblast Differentiation
... and Wnt/ β -Catenin pathways act on osteoblast precursors to promote bone ...osx expression while having a lesser effect on runx2 and bone matrix ...and Wnt/β-Catenin dependant expression of ...
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Stromal upregulation of lateral epithelial adhesions: Gene expression analysis of signalling pathways in prostate epithelium
... probe expression values were then calcu- lated using the perfect match (PM)-only model accord- ing to Chambers et ...based expression: 1) the fold change between the group means was chosen to exceed ...
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Artificial neural networks for linkage analysis of quantitative gene expression phenotypes and evaluation of gene × gene interactions
... Heather J Cordell, Mariza de Andrade, Marie-Claude Babron, ...
Genetic Analysis Workshop 15: Gene Expression Analysis and Approaches to Detecting Multiple Functional Loci
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The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction
... posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction Bo Li*, Sei Kuriyama*, Mauricio Moreno and Roberto Mayor † Wnt signalling ...
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Wnt/β catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse
... Several signalling cascades are implicated in the formation and patterning of the three principal germ layers, but their precise temporal-spatial mode of action in progenitor populations remains ...conditional ...
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Quantitative Expression and Co-Localization of Wnt Signalling Related Proteins in Feline Squamous Cell Carcinoma
... Data Availability Statement: All relevant data are within the paper and its Supporting Information files. Funding: This research was funded by the Prostate Cancer Research Centre charity (registered UK charity no. ...
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Genome-level analysis of genetic regulation of liver gene expression networks
... The other candidates for the master regulator at the chromosome 12 locus are Serpina3-family genes. These genes are the murine orthologs of human α1-anti- chymotrypsin, a serine protease inhibitor. Serpina3n is an acute ...
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