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GENE FAMILY

Comprehensive Variant Screening of the UGT Gene Family

Comprehensive Variant Screening of the UGT Gene Family

... Purpose: UGT1A1, UGT2B7, and UGT2B15 are well-known pharmacogenes that belong to the uridine diphosphate glucuronyltransferase gene family. For personal- ized drug treatment, it is important to study ...

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A review of the new HGNC gene family resource

A review of the new HGNC gene family resource

... the family and records the root symbol if one ...the family even when they do not know the precise name we have ...of family members is based on a particular paper or where a paper is particu- larly ...

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Identification of Cyclophilin gene family in soybean and characterization of GmCYP1

Identification of Cyclophilin gene family in soybean and characterization of GmCYP1

... I identified members of the Cyclophilin (CYP) gene family in soybean (Glycine max) and characterized the GmCYP1, one of the members of soybean CYP. CYPs belong to the immunophilin superfamily with ...

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Prokaryotic gene-family size correlations

Prokaryotic gene-family size correlations

... A genefamily is a set of sufficiently similar genes, formed by gene ...of gene family and size of genome are positively ...of gene copies would have lower  ...

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Update on the Kelch-like (KLHL) gene family

Update on the Kelch-like (KLHL) gene family

... (Kelch-like) gene family encodes proteins that constitute a subgroup at the intersection between the BTB/POZ domain and Kelch domain ...49 family members in the latter two ...

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Characterization of the Aspergillus nidulans Septin (asp) Gene Family

Characterization of the Aspergillus nidulans Septin (asp) Gene Family

... septin gene family have been found in the site of bud emergence and at the base of the mating budding and fission yeast, fruit fly, worm, mouse, and projection, or schmoo (Haarer and Pringle 1987; Kim human ...

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The gene family-free median of three

The gene family-free median of three

... of gene family evolu- tion on the gene order must be accounted for in gene order ...the gene fami- lies are inferred. Consequently, family-free methods must provide internal ...

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Functional Evolution of the Vertebrate Myb Gene Family

Functional Evolution of the Vertebrate Myb Gene Family

... following gene duplication within the vertebrate Myb gene ...putative gene duplication ...A-Myb/c-Myb gene acquired the transcriptional activation domain (red, center) and likely a new ...

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The ALMT gene family performs multiple functions in plants

The ALMT gene family performs multiple functions in plants

... (ALMT) gene family is named after the first member of the family identified in wheat (Triticum aestivum ...this gene controls resistance to aluminium (Al) ...this family. In this ...

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Molecular and evolutionary investigation of the phosphoglucomutase gene family

Molecular and evolutionary investigation of the phosphoglucomutase gene family

... a gene family may have occurred in a variety of ways: from non-homologous chromosomal breakage and reunion, unequal but homologous crossing over between two repeated sequences either side of the ancestral ...

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Structure and Evolution of the Actin Gene Family in Arabidopsis thaliana

Structure and Evolution of the Actin Gene Family in Arabidopsis thaliana

... Actin is encoded by 10 genes in A. thulium: A primary goal of this study was a thorough analysis of actin gene family structure in Arabidopsis. Hybridization of actin coding s[r] ...

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Evolution of the multifaceted eukaryotic akirin gene family

Evolution of the multifaceted eukaryotic akirin gene family

... akirin2 gene was ...a gene family member, rather than repeated artefacts of insuffi- cient sequencing ...of gene family members common to tetrapods/teleosts is markedly reduced in the ...

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Population genetics of the highly polymorphic RPP8 gene family

Population genetics of the highly polymorphic RPP8 gene family

... RPP8 gene family on nucleotide diversity, we modified SeDuS, a two-locus forward-in-time simulator of population genetics in a duplicated gene family undergoing IGC [49], to accommodate three ...

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Characterizing gene family evolution

Characterizing gene family evolution

... level, gene families must be constructed (see above). In evaluating if a gene belongs in a gene family, distance constraints are typically used (for example in single or multiple linkage ...

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CRISPR Cas9 Mediated Single Gene and Gene Family Disruption in Trypanosoma cruzi

CRISPR Cas9 Mediated Single Gene and Gene Family Disruption in Trypanosoma cruzi

... enzyme gene family consisting of 65 members, resulting in a significant reduction of enzymatic prod- uct with no apparent off-target ...of gene functions in ...

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The Drosophila retained/dead ringer gene and ARID gene family function during development

The Drosophila retained/dead ringer gene and ARID gene family function during development

... ARID family of proteins interact with DNA through a phylo- genetically conserved sequence termed the A/T Interaction Domain ...(retn/dri) gene of Drosophila melanogaster is a founding member of the ARID ...

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Analysis of the glutathione S-transferase (GST) gene family

Analysis of the glutathione S-transferase (GST) gene family

... It will be shown that the remaining five genes — GSTK1, PTGES and the three microsomal GSTs — are not evolu- tionarily part of the GST gene family. Phylogenetic analysis (Figure 1) places these five genes ...

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Gene family matters: expanding the HGNC resource

Gene family matters: expanding the HGNC resource

... HUGO Gene Nomenclature Committee (HGNC) assigns approved gene symbols to human ...approved gene symbols, the majority of which represent protein-coding genes, but we also name other locus types such ...

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Molecular evolution of the plant R regulatory gene family.

Molecular evolution of the plant R regulatory gene family.

... Evolution of the R variable domain in the grasses: Analysis of the isolated grass R homolog sequences re- veal that several mostly conservative amino acid replace- ments[r] ...

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The Hes gene family: repressors and oscillators that orchestrate embryogenesis

The Hes gene family: repressors and oscillators that orchestrate embryogenesis

... Notch family members are type I transmembrane receptors for the DSL (Delta, Serrate, Lag-2) family of type I transmembrane ligands (Artavanis-Tsakonas et ...(DSL family) expressed on the surface of ...

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