Gene Pairs
Finding prognostic gene pairs for cancer from patient-specific gene networks
... dom gene expression signatures are more predictive than known breast cancer signatures and that such random signatures are significantly associated with proliferation ...prognostic gene pairs with ...
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Ranking novel cancer driving synthetic lethal gene pairs using TCGA data
... lethality pairs for further experimental validation represent an attractive ...SL gene pairs by mining vast amounts of accumulated tumor high- throughput sequencing data in The Cancer Genome Atlas ...
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Sense-antisense gene-pairs in breast cancer and associated pathological pathways
... Wrap53 gene mRNA [8], which might be relevant in many ...cis-antisense gene NCYM is associated with poor prognosis in neuroblastoma via promotion of production of anti-apoptotic protein Myc-nick ...of ...
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Orthology-Based Multilevel Modeling of Differentially Expressed Mouse and Human Gene Pairs
... single gene, and there is no guarantee that these probe sets will behave in a consistent ...the gene level. Consequently a gene-level summary is necessary for the cases where multiple probe sets are ...
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Qualitative transcriptional signatures for evaluating the maturity degree of pluripotent stem cell-derived cardiomyocytes
... Entrez gene ID according to the platform ...zero gene, then the data of this probeset was ...same gene, the expression value for the gene was defined as the arithmetic mean of the value of ...
7
Uncovering synthetic lethal interactions for therapeutic targets and predictive markers in lung adenocarcinoma
... SL gene pairs as novel therapeutic targets of lung adenocarcinoma ...SL pairs, PARP1-TP53 was validated by RNAi knockdown to have synergistic toxicity in H1975 and invasive CL1-5 LADC cells; ...
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An Alternative Analysis on Nilsson Ehle’s Hybridization Experiment in Wheat —Theory of Dual Multiple Factors and Three Normal Distributions on Quantitative Inheritance (Continuation)
... 2 gene pairs was crossed with white seed variety in wheat, the variation in grain color was explained with the help of additive effect ...3 gene pairs, for example, the inheritance of 3 ...
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Accurate molecular classification of cancer using simple rules
... and gene pairs in constructing cancer classifiers; however, in contrast to [17], we first aimed to use the con- cept of canonical depended degree, as proposed in rough sets for gene ...for ...
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lecture 10
... – Segregation: genes become separated in gamete formation – Independent Assortment: Members of one gene pair. segregate independently from other gene pairs during gamete formation.[r] ...
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A novel independence test for somatic alterations in cancer shows that biology drives mutual exclusivity but chance explains most co occurrence
... Many gene pairs that are believed to be co-altered more often than expected by chance do not exceed this expecta- tion if the confounding effect of tumor-specific alter- ation rates is taken into ...
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Online Full Text
... Global gene expression profiles of cell transcriptomes, measured by DNA microarrays, are used to diagnose and classify human cancers into genetic sub-types related to different clinical outcomes, as well as to ...
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Patterns of regulation of gene expression and genetic novelty in mammalian species
... frequency of expression bias in human and mouse duplicate genes.. revealed a greater likelihood for gene pairs with dispersed locations to show.[r] ...
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Fully automated protein complex prediction based on topological similarity and community structure
... We compared our algorithm with four existing methods, namely Euclidean commute time (ECT) [24], random walk with restart (RWR) [25], multiple dimensional scaling (MDS) [26], and global geometric affinity (GGA) [27]. The ...
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Genomic positions of co expressed genes: echoes of chromosome organisation in gene expression data
... to gene densities from all groups of positional clusters considered ...of gene densities (counted in genes per 1 Mbp) was calculated and the mean of all standard deviations was ...of gene densities ...
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Transcriptional Compensation for Gene Loss Plays a Minor Role in Maintaining Genetic Robustness in Saccharomyces cerevisiae
... it has been previously observed for several SSL gene pairs (T erashima et al. 2000; L esage et al. 2004; K afri et al. 2005). To systematically identify additional cases, we again considered M:G ...
5
Conservation of an Intact vif Gene of Human Immunodeficiency Virus Type 1 during Maternal-Fetal Transmission
... vif gene is conserved among most lentiviruses, suggesting that vif is important for natural ...vif gene is positively selected during mother-to-infant transmission, we analyzed vif sequences from five ...
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Low diversity of Angiostrongylus cantonensis complete mitochondrial DNA sequences from Australia, Hawaii, French Polynesia and the Canary Islands revealed using whole genome next generation sequencing
... Abbreviations aa: amino acid; bp: base pairs; cox1: gene for subunit 1 of cytochrome c oxidase; cox2: gene for subunit 2 of cytochrome c oxidase; cob: gene for cytochrome b; mtDNA: mitoc[r] ...
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Molecular Evaluation of Primary and Secondary Resistance of M. Tuberculosis in Senegalese Patients by Seegene AnyplexTMII MTB/MDR/XDR
... Background: Drug-resistant TB has become a public health problem. In 2017 WHO estimates that 3.6% of new TB cases and 17% of previously treated cases were multidrug-resistant (MDR-TB). However, 8.5% of people with MDR-TB ...
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Codon pairs of the HIV 1 vif gene correlate with CD4+ T cell count
... BC-Box and Cullin5-Box (filled diamonds in the Figure 1). In addition, a dataset of vif sequences (n=33) from hypermutated viruses, based on the integrase gene, was analyzed to explore the selective regime. ...
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Detection of low rank signals in noise and fast correlation mining with applications to large biological data
... is gene expression quantitative trait loci (eQTL) mapping, which searches for associations between SNPs and ...on gene by gene ...given gene expression with the available SNPs is assessed ...
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