genome wide association study
Lecture 7: Genome-wide Association Study
... Genome-Wide Association Study (GWAS) — 27/37 — GWAS: independent single-variant tests across all genome-wide variants • Quality control (QC) of the study dataset • Choose ...
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A genome-wide association study of anorexia nervosa.
... Title: A genome-wide association study of anorexia nervosa. Authors: Boraska V, Franklin CS, Floyd JA, Thornton LM, Huckins LM, Southam L, Rayner NW, Tachmazidou I, Klump KL, Treasure J, Lewis ...
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A genome-wide association study of bronchodilator response in asthmatics
... recent genome-wide association study (GWAS) of BDR by our group identified a functional variant in the serine- rich 2-like (SPATS2L) gene, albeit the mechanism by which it regulates BDR ...
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Genome-Wide Association Study of Polymorphisms Predisposing to Bronchiolitis.
... a genome- wide association study (GWAS) in which 5,300,000 single nucleotide polymorphisms (SNPs) were tested for association in a Finnish–Swedish population of 217 children ...
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A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism
... a genome-wide association study (GWAS) to identify novel genetic variants influencing nicotine metabo- ...Finns Study, FIN- RISK2007), followed by a meta-analysis of 1518 subjects, and ...
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Semantically enabling a genome-wide association study database
... 16. Hughes LM, Bao J, Hu ZL, Honavar V, Reecy JM: Animal trait ontology: The importance and usefulness of a unified trait vocabulary for animal species. J Anim Sci 2008, 86(6):1485 – 1491. 17. Newton-Cheh C, Johnson T, ...
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Genome-Wide Association Study of Parity in Bangladeshi Women
... our genome-wide association study of number of pregnancies and number of children in Ban- gladesh did not confer strong evidence of common variants for parity ...
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Genome wide association study of Alzheimer's disease with psychotic symptoms
... Genome-wide Association Study of Alzheimer’s disease with Psychotic Symptoms Paul Hollingworth 1,16 , Robert ...Family Study Group12, Peter Holmans 1 , Lesley Jones 1 , Bernie Devlin 2 ...
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TDT for Human QTL Mapping and Genome - Wide Association Study
... to genome- wide association study has not been tackled so ...to genome-wide association ...linkage study for gene mapping to variable selection ...simulation ...
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A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice
... controls genome plasticity, which is important for recombination during the processes of immunity and ...the genome, yet subtle differences in the level of genomic instability can contribute to whole ...
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A genome-wide association study for corneal astigmatism: The CREAM Consortium
... Consortium. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM ...
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Genome-Wide Association Study for Mid-Salt Tolerance in Rice
... to study the natural variation of a worldwide japonica rice collection in response to mid-salt ...A genome wide association study (GWAS) highlighted the presence of significant loci ...
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A genome-wide association study on medulloblastoma.
... carriers of the risk allele had a more than two-fold increased risk. Our findings were not statistically significant when using the p value threshold p < 5 × 10 –8 to correct for mul- tiple comparisons. Although a ...
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A Genome Wide Association Study for Longevity in Cattle
... Genomic associations for longevity were studied using deregressed breeding values from 4887 Fleckvieh bulls and 33,556 SNPs with a single SNP approach. A correction for population structure using 103 eigenvectors led to ...
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Progress of genome wide association study in domestic animals
... Conclusions In summary, there was a great progress of GWAS in do- mestic animals and some genes for economically import- ant traits have been identified. However, the main problem lies in the inconsistencies among the ...
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Genome wide association study for multiple phenotype analysis
... Abstract Genome-wide association studies often collect multiple phenotypes for complex ...score-based association test to incorporate family structure, apply different approaches to analyze ...
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A genome-wide association study in multiple system atrophy
... reported association of variants at the SNCA. 8,22,23 A Korean study was also unable to reproduce the association indicating possible differences between populations or an actual null ...Our ...
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Genome-wide association study of male sexual orientation
... This work was supported by NICHD: the Eunice Kennedy Shriver National Institute of Child Health and Human Development (A.R.S., grant no. R01HD041563 for the Affymetrix 5.0 genotyped sample and A.R.S. and E.R.M., grant ...
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Genome-wide association study in Guillain-Barré syndrome
... Given the previous reported associations of GBS with HLA alleles, we investigated these and the MHC region more closely. A total of 8,961 SNPs within the MHC region, HLA alleles and their composite amino acids were ...
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Genome-wide association study of antisocial personality disorder
... identical genotypes as the GWAS genotyping with 499% concordance between the two methods. In a post hoc repeat GWAS analysis, including the CRIME subjects and GenMets controls, the results were consistent with the ...
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